r/DoctorsAdvice

▲ 2 r/AskDocs+1 crossposts

Unexplained fatigue and panic-like symptoms despite normal tests — physical or anxiety?

TL;DR:
35-year-old man, generally healthy lifestyle, experiencing unexplained episodes for ~10 years: fatigue, shortness of breath, lightheadedness, and panic-like sensations (especially at night with feelings of imminent death). Extensive medical tests (cardiac, brain, sleep, etc.) all normal. Symptoms started after father’s death from leukemia and a history of family health trauma. Has explored psychological causes without clear results. Unsure whether the issue is physical or anxiety-related; looking for similar experiences or explanations.

Hello, I need help diagnosing myself. It’s going to be quite long to explain all the context, sorry in advance.

To start, I am a 35-year-old man, 1m83 tall and 82 kg, trying to stay fairly active physically, although have been working a desk job for ten years now. My main physical activity is a few fitness sessions per week and walking. I have a little abdominal fat, but overall I'd say I'm in good shape. I have a quite full life, with a friends, family, girlfriend, cats, traveling and more projects for the future.

For about ten years now, I’ve been experiencing situations where my body seems to give out on me or puts me in unpleasant and not always easily explainable states. Up until I was 25, I always felt quite physically fortunate — I could always rely on my body, I was fairly athletic and in shape, I was always running around and climbing several flights of stairs with very little effort.
At 25, my father fell ill with leukemia and passed away within a year. Around that time, I started waking up at night in a panic with a feeling of imminent death and strange sensations around my heart — like an overload, a surge, a kind of nervousness, as if a big wave was coming and I was about to die, or that something was about to happen. After that, this phenomenon happened many times sporadically, and sometimes nothing for months. But many other symptoms also appeared since then, quite varied, but often involving feelings of weakness in the heart area or in the body in general; a feeling of not having enough energy even to speak, shortness of breath, intense fatigue while walking, even a kind of lightheadedness after eating. A sort of fatigue could sometimes overwhelm me after moderate physical activity like cycling — but sometimes not, even with the same activity. My lifestyle is quite healthy: diet, hydration, sleep, etc. I don’t consume alcohol, drugs, or take any regular medication.

All of this gradually started to complicate my life and affect my choices, even though I am still trying to live it fully and I'm quite happy overall. I began avoiding certain activities or going on vacation with certain people because I didn’t want to be a burden — suddenly tired “for no reason” and needing to rest for three days straight. I find it hard to talk about because it feels strange, not very rational, and difficult to explain. I even oriented my professional life toward an office job because at least it limits physical effort and reduces the risk of drawing attention when I experience these states of fatigue or lightheadedness.

Over the past ten years, I’ve consulted many professionals across different fields: medicine, psychotherapy/psychology, hypnotherapy, alternative medicine, and spirituality. I’ve undergone quite a few tests such as: brain MRI, several complete cardiac evaluations over the years, a sleep apnea test, gastroscopy and colonoscopy, common allergy tests, general check-ups, and blood tests. None of these examinations have revealed any dysfunction, abnormality, or weakness. Over the years, I have also followed several therapies with different psychologists and psychotherapists to explore the anxiety/psychosomatic angle, but so far I don’t feel it has been very conclusive.

What might support the anxiety hypothesis is that I have seen several people in my family suffer from illnesses, in addition to my father. At 16, I saw my mother collapse and scream due to a recurrence of a brain tumor, for which she was successfully operated on, but which still physically weakened her. During my teenage years, I also witnessed my sister having epileptic seizures several times. It was quite traumatic for me, and I think that along with my father’s death, it made mortality very real — and since then I feel quite hypochondriac.

What I cannot clearly determine is whether all of this is mental/psychological in nature or purely physical. Has anyone experienced something similar and been able to find causes and/or solutions ?

I know my post must lack a lot of information to be able to make a clear assessment, even more trying to do so over the internet. And of course the best thing to do will be to keep exploring all this with professionals, but I thought it could maybe help to have some insights by people who might recognize themselves in my post.

Thank you in advance for your help.

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u/Alert-Educator-1156 — 3 hours ago
▲ 6 r/jaipur+1 crossposts

Sharing this because CT scan ko leke kaafi log unnecessarily panic kar jaate h

CT scan ka naam sunte hi kaafi log tension me aa jaate h but generally process utna scary nahi hota jitna log soch lete h.

Agar mai simple way me samjahu to CT scan body ke andar ka detailed view dene ke liye hota hai aur kaafi cases me jaldi ho jata hai Kabhi contrast lagta hai, kabhi nahi wo case pe depend karta h.

I am sharing the graphic content what I found on google and its interesting to know who anyone recently wants to go for this scan.

https://preview.redd.it/dtg5398jkhug1.jpg?width=1080&format=pjpg&auto=webp&s=edce626d14f986d1e84d3f80489469ee06332617

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u/ranug21 — 9 hours ago

Ear specialists, please help!

PLEASE READ THIS,My eardrum is already problematic, my left ear specifically, I had a bad flu and it resulted in an infection buildup in my ear, I went to urgent and I had a painkiller through an IV because it so bad I was screaming out of pain, it didn't work as fast as I wanted, anyways I went back home and suddenly my eardrum bursts, yes you heard that right, it literally BURST AND TORN! And I had a bleeding for like three days after, I went to a specialist and had an ear drop, he told me to be careful when showering and not swim to prevent water entering my ear, the usual advice anyone would give, a few months later I went back and it was loosely closed, with that small camera we saw that my eardrum moving in and out when breathing, the dictor told it's healing on its own -even though I think nothing changed till now- so there may be no need for a surgery (which my parents got at an old age and had side effects, they wouldn't even let me consider that choice) Fast forward, it's been more than a year since this happened, I still have random ear stings, very bad head spinning, imbalance and dizziness, evertime I sneeze I need to be extra careful to sneeze out my throat so my ear won't burst open, that causes irritation in my throat, when I blow out my nose I need to be careful too, this has caused some pain too as well, let alone minor and or sudden pressure changes when in the car, so swimming deep is NOT a good option for me, I missed so many amazing swimming chances this summer just because of this shitty problem, I don't want to suffer my whole life with this, I want to fix it right away even if it comes with minor hearing loss, I'd rather take that over having such annoying problems that take over my day and ruin it, my parents are still very strict about not letting me take the "risk" based on their experience, any specialist, please give your opinion or advice

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u/malakhsn07 — 4 hours ago

Is this cancer?

I have this mole on my nose that wasnt there before. Could it be cancer or something harmful?

u/k0they — 5 hours ago
▲ 3 r/AskDocs+1 crossposts

Should I worry about tetanus

F33 5’7

I’m in Japan, and was just looking through an antiques store and my finger got punctured by a rusty nail. No blood, no access to soap and water so I poured anti bacterial spray all over it.

I haven’t had a tetanus shot since I was 17, should I be concerned and go and try and find somewhere to get one?

Thanks!

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u/Embarrassed-Grape404 — 11 hours ago
▲ 4 r/DoctorsAdvice+1 crossposts

I have pernicious anemia but some things aren’t getting better

So I got diagnosed at 22yo with pernicious anemia after going to the hospital because my legs stopped working and i had terrible pressure behind my left eye, they first diagnosed me with MS but the MS specialist i went to said no no no thats very wrong. My b12 was at 116 and my ferritin was at 6. I had to have weekly b12 injections and iron infusions and now im 25 and inject myself monthly. Heres my problem i still have terrible symptoms that didnt get better… and i dont know what to do. First off my numbers monthly are awful, i inject and go up to like 600 and then am back to 200-300 at the end of the month, I saw an eye doctor because i lost my peripheral vision and turns out my ocular nerve is paling… my muscles cramp up and i disassociate really bad when its almost time for my injection… I also feel like im suffocating and dizzy ALL THE TIME its awful, i get like 1 week of feeling good and then im suffering again, why isnt it getting better and will my legs and fingers ever work right again, will my ocular nerve ever get better? What do i need to do… oh and im also VERY tachycardic like resting heart rate of 100 laying down, and up to 150 when i stand. Please help. Im just want to be healthy again :(

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u/Justwaiting121211 — 13 hours ago
▲ 2 r/AskDocs+1 crossposts

Long Term Nerve Pain/Inflammation/Tingling Burning

Hi there. I am going to try to condense this story for the sake of whichever kind soul is reading this. For context, I am M23 ~160 lbs, 5'10, and I smoke weed/pens daily. Potentially relevant conditions are; my dads family has a long history of substance abuse. my mom has Multiple Sclerosis and has passed me Polycystic Kidney Disorder to some degree. I lift heavy weights everyday and I am a college student.

About a year ago as of me typing this, I feel a random tingling sensation in my feet at night and I assume it's some bugs my dog has brought into my apartment, but it never goes away. A day or so later I feel it travel across the rest of my body and then suddenly become incredibly intense and painful, it felt like I was being violently bit by something all across my body constantly, back, feet, chest, everywhere. I don't know what's going on so I investigate the bug theory for a while and there's no bugs of any kind to be seen and no microscopic fellas in my space either. This lasted for a few months, I then take myself to a family practice near my work for help and for the next 6-8 months I've been going through the insane referral process going from specialist to specialist and medication to medication trying to diagnose what is going on with me.

As of then the pain and discomfort is still constant and incredibly debilitating, I feel it in my feet moreso than anything but the burning and pulsating feeling is in all my extremities and across my thighs/chest at random. The burning and tingling in my feet is by far the most prominent.

I have done;

MRI of my Brain, 3 separate MRI's of my back/spine, EMG Nerve Compression Study

Taken;

Escitalopram, Gabapentin, Pregabalin, Dulexotine, Prednisone

Been to;

PCP, Psychiatrist, Nuerologist, Podiatrist

And with incredibly mixed experiences I have allegedly ruled out my symptoms being a cause of, HIV, MS, PKD, Infection, and Nueropathy. I have benign csyts on my kidneys but my mother has an absurd amount on hers but has never had my symptoms, I tested negative for HIV, and none of the doctors suspect MS because I have not been peeing blood, fainting, or shown any other obvious MS signals.

My pcp says the nerve compression study showed nothing of interest, but that there was mild macular degeneration in a spinal section of my MRI. I also would often feel the pulsating sensation in one specific spot on my spine during this entire experience which makes me suspect I did indeed compress something there from weightlifting, which then causes the inflammation in my extremities. My doctor seems to not think so.

There was also an elevated white blood cell count shown when I got my blood drawn early in this experience. But nobody seemed to think it was important.

________

And now i'm here, I am seeing a pain specialist in a few days, praying that they will have some kind of help for me because the inflammation, burning, tingling and pain is a at a new high right now, and I am at a complete loss of what to do other than wait and hope. This has been the hardest year of my life and if anybody here has help for me. I would be oh so deeply grateful.

I want to specify that while my symptoms have been very discomforting and often painful. I haven't had any kind of motor issues or functional problems with my body, I still lift as heavy as I did, I am still able bodied and can walk, run, and do daily tasks, I just am utterly discomforted 24/7.

If there's anything else I should share for context please please do ask.

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u/Chibikyu — 8 hours ago

Worried about how badly this will scar ?

Hi all! In desperate need of advice/ reassurance,

Today I had a freak accident and a steak knife fell from a high shelf on to my face cutting my nose open pretty badly. I went to the emergency room and got 6 stitches across my nose, the doctor did an incredible job and made sure to line everything up as perfectly as she could. I have attached a picture, I would love any feedback on how bad scarring will be as it’s so prominent on my face I’m really nervous, emts and the doc said it wouldn’t be too bad and would be barely noticeable but I just want some other opinions as well.

Thanks so much

u/Adept-Juggernaut9929 — 10 hours ago
▲ 2 r/DoctorsAdvice+1 crossposts

Help! I have a solo coming up

I need some quick, efficient, simple remedies to get rid of the sickness that I have had for almost a week now.

My symptoms are coughing, runny nose, sneezing, fatigue, sore throat.

I have a solo performance coming up in about two weeks and I don’t want to damage my vocal cords from coughing a lot or missing any more of rehearsals due to me being sick.

The medicines that I’m currently taking are allergy pills (Zyrtec), Sudafed and Guaifenesin.

I have been drinking tea every morning(all day). I’ve recently added bay leaves and ginger to my pink tea with hibiscus leaves and cloves.

This morning, I just started eating a piece of garlic and doing olive oil, lemon shots. I couldn’t get any sleep last night due to coughing up mucus and blowing my nose. I’ve ran out of tissue.

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u/No-Blacksmith-6798 — 10 hours ago
▲ 2 r/AskDocs+1 crossposts

Blood results for 16 month old boy

My 16 month old son, 26 pounds, has a history of recurrent illness. He started daycare in July of 25 at 7 months old and caught every illness under the sun, as well as pneumonia 3 times in a span of 6 months. This prompted his pediatrician to order blood tests to check for inflammation for markers of possible immunodeficiency. We got his bloodwork done today (CBC w/diff, CMP, and Sed rate or ESR). The most concerning things for me were his ESR came back very elevated at 73mm/Hr (normal below 20) & his platelets came back elevated at 466. His hemoglobin was low as well as his BUN. While his Albumin was elevated. I have no idea what any of this means and most likely wont receive any feedback from his doctor until Monday. What could these results possibly mean? Signed, An anxious spiraling momma!❤️

https://imgur.com/a/EYG8KC7

u/No_Inspection9413 — 13 hours ago
▲ 2 r/AskDocs+1 crossposts

Did i catch HSV-1?

24M , healthy and not immunocompromised, never had an HSV outbreak of any type whatsoever. My girlfriend 23M has oral HSV-1 and didn’t know that HSV-1 can be genital as well, she’s towards the end of an outbreak and has one sore of her inner lip, she has been taking 2g BID of valacyclovir for the last few days, so while laying together she proceeded to give me oral and I abruptly stopped her but she had already licked (no lip contact) my penis for literally ONE second not more, I didn’t know she’s oblivious to the the fact that HSV-1 is not strictly oral otherwise I would have stopped her earlier obviously. I got up and washed the area with soap right after. Is this 1-sec tongue contact enough to transmit the virus to a non-immunocompromised person? I started to take Valacyclovir 2g BID and plan to do so for the next 5 days in case that helps although I’m aware there is no agreed upon PEP regimen for HSV. Thank you in advance

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u/Flimsy-Impact9110 — 14 hours ago

Air hunger that won’t resolve despite reassurance

37F, approximately 5’6, 180 lbs,

Medications: Zoloft, Caplyta, magnesium glycinate, L-theanine, prenatal multivitamin.

I have a history of anxiety and depression, currently managed with medication. For some time now I’ve been experiencing what I can only describe as “air hunger” — a persistent sensation that I cannot get a satisfying breath, like I’m not inhaling deeply enough no matter how hard I try. It does not feel like shortness of breath in the traditional sense; I’m not gasping or unable to speak. It’s more of a compulsion to take a deep breath, and even when I do, it only provides brief relief.

It tends to be worse when I’m at rest, sitting quietly, or trying to fall asleep. I know anxiety can cause this, and I suspect that’s a significant factor, but I’m wondering if there’s anything else worth ruling out or whether there are interventions beyond what I’m already doing for anxiety management.

No chest pain, no wheezing, no coughing, no fainting. No known cardiac or pulmonary history.

Is this purely anxiety-driven? Should I be pushing for any specific workup?

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u/WiseBreadfruit7779 — 10 hours ago

Medical mystery

I am in desperate need of some help diagnosing my grandmother. She's had a mysterious condition that started in 2019. I am going to list her symptoms and everything that has happened along with a list of things she has been tested for. Any input and suggestions are highly appreciated. 

My grandmother is a 78 year old otherwise healthy old lady, just not physically. Her legs has failed her. She is very short. Approximately 157CM and weighs 47KG If not less. She has lost a lot of weight during the condition but she has always been small.
In 2019 she started to have a sensation in her legs that made it feel like she was walking on pillows. Basically her balance wasn't very good. When you see her walk. You would assume she's blind drunk. In the beginning we all thought she had a drinking issue, but she's not drinking. I can't even explain how terrible it was for her. Even as she stood still her legs were going crazy and was like dancing/stomping and she’d lose her balance.

In 2021 she had 2 small insignificant disc herniations. She has gone to a lot of doctors and gotten a ton of tests but no one was able to find anything wrong with her

Here is a list of things she's been tested for:

Sclerosis
Muscle atrophy
Muscular arthritis
Brain tumor
Blood clot in the brain
Various nerve diseases
The balance nerve
She did get positive for a little bit of spinal stenosis
Nerve inflammation
She's had B12 supplements and didn't work

In the summer of 2025 she got a sudden strong pain that turned out to be two big disc herniations and she lost all the strength in her legs. She has been struggling to even stand as her legs cant hold her. She has walked around with a walker, however, she is stubborn so not always. Even with the loss of strength, she still managed to walk with her dog and do chores around the house every day. March 2026 she got operated for the big disc herniations and was still in pain but she is able to walk but still has 0 strength in her legs. In all of this time she has done exercises and done physical therapy to build strength in her legs but nothing has helped. We dont understand how she could lose all the strength in her legs from one second to another. It makes no sense. She is now hospitalized because her legs failed her and she fell and broke her hip. I am afraid she will never walk again. Its been an enormous pain for me and my family, to watch her suffer for 7 years and now shes hit rock bottom.

I am desperate to find a solution so if you are a doctor or know someone with similar experience, please, tell me your story. Tell me your suggestions and thoughts
ANYTHING is appreciated.

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u/Fit-Interest-6989 — 17 hours ago
▲ 2 r/AskDocs+1 crossposts

Ate a fork

I’m 26 5’9 male and 190 lbs. I accidentally think I swallowed a bit of this plastic fork while eating food. Based on the size do you think it should be okay? After it happened I started to google stuff and now my stomachs feeling kinda weird. Pls help

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u/Character-Yellow4968 — 18 hours ago

Left leg pain

I have been keeping a log of what I have been eating for the past two weeks now. I saw a specialist about this at an orthopedic Center and the specialist had said to write it down until I see him June 29. I get these feelings randomly in my leg after I eat anything it feels like inflammation, but I’m not sure why this happens. I recently went to my general doctor and he did a lot of bloodwork to my blood and he said my A1c levels are at a regular level. I don’t eat a lot of of sugar and I don’t eat fast food or anything like that. I will say, though I had a history of pre-diabetes and my highest weight was 230 pounds six years ago. I am 5 foot 23-year-old woman who weighs 125 pounds now. I came out with anemia, but I have been taking multivitamins that have iron every day and it’s been getting better. I’ve been having this leg feeling on and off going for about 2 to 3 years and I’m finally doing something about it because I feel like it’s getting persistent. This is my food log and how the pains have been making me feel. Has anyone been through this?

——————————————————————————————

March 31st

Breakfast 7:00am: Peanut Butter Overnight Oats - no leg/foot pain ( multivitamins included )

Lunch 1:15pm: Chicken Salad - no leg/foot pain

Dinner 8:30pm: stuffed ground beef bell peppers - no leg/foot pain

( Comments: was sitting down at 11:30am, with my left leg nerves starting to flare a bit for stretching leg towards the floor ) ( 1:14pm bottom left foot starts cramping after sitting down from a 30 min walk ) ( 1:35pm bottom of my foot feels pressure when walking ) ( 1:58pm getting pins and needles ranging from top foot to bottom foot after using restroom sitting on toilet and standing in room ) (6:00pm bottom foot feels a bit of pins and needles from sitting or laying down in bed )

————————————————————————

April

April 1st

Breakfast 6:20am: Protein Pruitt bebbles overnight oats - no leg/foot pain ( multivitamins included )

Lunch 11:20pm: ground beef white rice bowl with guacamole - no leg pain/foot pain

Dinner- 6:00pm-8:30pm: in and out burger and animal style fries, two pizzas, ice cream, popcorn - no leg pain/foot pain

( comments: throughout the morning, my leg didn’t hurt but I felt something off like if there’s a slight feeling below my foot of uncomfort. 3:00pm the feeling went away but tends to come back of a slight discomfort, more like tenderness.

—————————————————————————

April 2nd

Breakfast 9:05am: overnight oats strawberry blueberry (multivitamins included) - discomfort on my left wrist, feels burning pins and needles on my wrist. Lasted 5 mins. No leg pain

Dinner 6:20pm: chipotle chicken bowl with black beans, cheese, pico, white rice. No leg pain now but was feeling slight pins and needles below the foot. While eating food I felt my leg nerves twitching from time to time.

( comments: not much leg pain or foot pain today. )

—————————————————————————

April 3rd

Breakfast 5:10am: peanut butter banana overnight oats ( multivitamins included ) - no leg pain/body pains

Lunch 12:00pm: raising canes 3 piece combo with fries, bread, sauce - no leg pain/body pains

4:10pm: vanilla ice cream swirl

( comments: 2:30pm left top toes feels pressure. Was standing and walking all day due to working field trip. )

—————————————————————————

April 4th

Breakfast 9:40am: overnight oats banana blueberry cinnamon oats (multivitamins included) - left wrist discomfort slightly burning (lasted 10 mins)

Lunch 1:40pm: chipotle chicken bowl with black beans, white rice, cheese, pico de galo, siracha - no leg pain/body pains

Dinner 7:35pm: popcorn shrimp spinach salad with ranch, cheese, pico, and carrots - no leg pain/body pains

( Comments: did not feel leg pain today. I felt my left leg give me twitches on my left foot when I was laying down around 12:00ish. It lasted for 10 mins. )

—————————————————————————

April 5th

Breakfast 10:15am overnight oats banana blueberry (multivitamins included) - no leg/body pains

Lunch 5:30pm: cardne asada, chicken, queso fresco, beans, red rice, guacamole, chips and salsa - no leg pain/body pains

Dinner 8:00pm: bunny cake vanilla chocolate 1 slice - no leg pain/body pains

( Comments: today was okay. I didn’t feel any pains when eating and I had ate a variety of things. 10:24pm: I am sitting down on the chair and I am staring to get pins and needles once on my left ankle. I was sitting on my bed 5 mins ago with the feeling still flaring up. I feel my nerves on my left bottom leg starting to pulse. My left ankle is still getting pins and needles. 10:32pm: left bottom foot/toes feel aches.

—————————————————————————

April 6th

Breakfast 8:10am: Peanut butter banana overnight oats ( multivitamins included ) - no leg/body pains

Lunch 1:35pm: chicken salad with guacamole, cheese, carrots, cucumber, spinach, onion - bottom left foot to the left side is feeling slight burns. Started happening when eating. 1:53pm: slight bottom heel foot irritation. Feeling moves. 2:00pm feeling went away. Lasted 20 minsish.

Dinner 7:40pm: cardne asada tacos two with corn tortillas and quac with queso fresco - slight feeling on left ankle, irritated, small pins and needles feeling. Only ate one corn tortilla and a lil more meat from the other taco. I feel my veins pulsing through my left leg. 8:15pm feeling went away on ankle.

—————————————————————————

April 7th

Breakfast 8:55am: almonds with banana - no leg pain/body pains ( multivitamins included )

Lunch 1:37pm: chicken, white rice, asparagus - no leg pain/body pains

Dinner 6:20pm: popcorn shrimp, white rice, broccoli - while and after eating, my left foot on the bottom feels a little irritated when standing on it. While eating to I felt my left leg start to flare up while eating. Lasted 20 minutes

—————————————————————————

April 8th

Breakfast 8:00am: almonds, and apple ( multivitamins included ) - no leg pain/body pains

10:21am small Hawaii cookie - left top tigh feels sore. Leg feels like it’s flaring up but no pains lasted 5 mins

Lunch 1:07pm: popcorn shrimp, chicken, white rice, broccoli - no leg pains/body pains but felt it flare while eating. Was happening when eating. A few nerves twitched as well when eating.

Dinner 6:33pm: chicken breast, pico de galo, half an avocado 2 corn tortilla - nerves throbbing on left top leg. Bottom nerves throbbing. - no leg pains/body pain

—————————————————————————

April 9th

Breakfast 7:57am: Apple, almonds ( multivitamins included ) - a bit flares while eating but no leg pains/body pains

Lunch 1:35pm: broccoli, asparagus, asada meat, chicken - leg was flaring up while eating but no leg pain.

Dinner 6:37pm - strawberry cereal with banana and milk - feeling flares while eating and nerves throbbing on left leg. No leg pain/body pains

—————————————————————————

April 10th

Breakfast 8:00am: almonds, banana and milk shake, 8:15am: leg feels like it’s flaring up after using milk, banana and cinnamon sugar. 8:32am: putting pressure on left bottom foot feels irritated. 9:00am: leg feeling went away

Lunch 1:37pm cardne asada, chicken, asparagus, broccoli - left leg was flaring up while eating. Still feels an uncomfortable from time to time when walking like soreness.

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u/Empty-Alternative755 — 11 hours ago
▲ 2 r/DiagnoseMe+1 crossposts

Getting nowhere with doctors - any ideas?

I feel sick all of the time. The doctors can’t give me a diagnosis. I’m seeing if anyone here recognizes these symptoms or a pattern.

Core Problem (2+ years):

- Chronic flu-like myalgias

- Severe fatigue with post-exertional worsening (exercise consistently exacerbates symptoms, never improves them)

- Significant exercise intolerance

No meaningful response to standard therapies.

Persistent hyperandrogenemia (TT 1000–1280, elevated free T despite high SHBG) + elevated CK + post-exertional myalgia/fatigue – normal EMG, MRI, muscle biopsy – no exogenous androgens

Demographics:

- Adult male, previously active

- No history of testosterone, anabolic steroids, SARMs, or hormone use

---

Key Objective Findings:

- Creatine kinase (CK): persistently elevated (peaks ~642), including at rest

- Total testosterone: persistently elevated 1000–1280 ng/dL over >2 years

- Free testosterone: elevated (~21.65 ng/dL)

- SHBG: elevated (~61 nmol/L)

- Prolactin: mildly elevated (~17.6)

- RBC: ~5.88 x10⁶/µL

- Hematocrit: ~50–51.5%

---

Normal / Negative Workup:

- Thyroid panel: normal

- EMG: normal

- Muscle biopsy (deltoid): normal

- Brain MRIs (multiple): normal

- Genetic testing: unrevealing

- Ferritin and routine labs: normal

---

Symptoms NOT Present / Clarifications:

- Normal libido despite high testosterone

- No exogenous androgen exposure

- No obvious clinical signs of androgen excess

---

Treatments Tried (No Benefit):

- Duloxetine

- Gabapentin

- Low-dose naltrexone (LDN)

- Exercise → consistently worsens symptoms

---

Why This Seems Atypical:

- Persistent CK elevation + post-exertional worsening strongly suggests underlying muscle pathology despite normal EMG and biopsy

- True hyperandrogenemia (elevated total + free T even with elevated SHBG) without exogenous source is unexplained

- Mild hyperprolactinemia raises possible pituitary axis involvement

- Borderline polycythemia may be secondary to androgen excess

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u/RSW52299 — 18 hours ago

Can anyone help explain some answers to me about norethindrone acetate?

I have been taking a birth control called Jencycla or norethindrone 0.35 mg because of endometriosis. To be honest it has not helped that much with the pain, but I know that progesterone and birth control does help some people.

I recently received a prescription for norethindrone acetate 5 mg which has been approved by the FDA for treatment of endometriosis and is a higher amount of a similar thing.

But I wanted to find out - does anyone know if norethindrone acetate is the same as Depo-Provera and Lupron? (hormonal treatments for endometriosis which I did not want to take because of certain long-term negative side effects)

I am also confused because some people said it is not birth control and other people said it technically is because it's a higher dose of norethindrone which is a birth control. (I might have seen that it was not FDA approved to be used as a birth control but does the same thing as birth control?)

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u/throwawayhey18 — 13 hours ago

Oil burn on arm

I recently got a large burn from hot oil on my forearm, and it was just appeared like a first degree burn where it was red and swelled and then cooled down a bit, however two days later I noticed smaller blisters are forming. Is this normal or did I do something wrong to cause it, cause I usually keep it wrapped with gauze but for the second day I removed it to shower and then put it back on afterwards. I’m planning to see a GP but the next appointment I can do is in 4 days.

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u/Ill-Pin974 — 17 hours ago

Possible ovarian cancer

Hello, I hope this post is appropriate.

I'll just start at the beginning. Back in December I went in for a physical. During the abdominal exam the doctor found a sensitive area right where my right ovary and appendix would be. She did all the things to test if it was my appendix or possibly kidneys. Nothing.

So she started asking about different symptoms I might be having. I couldn't really answer most of the questions because I'm always so dang busy and exhausted all the time. She looked kinda freaked out and wanted to do a CT. I fobbed her off and said it's probably a cyst and will pass.

She told me if it persists or gets worse to call her. Well about three months later the pain is still there. When I contacted the doctor I thought it had only been a month. I was palpitating the area regularly, waiting for my cycle to pass and see if the pain subsided.

It didn't. It actually got to the point where if I did palpitate the area, it would ache all day. It's easily identified as the ovary now, I've had so many cysts in the past. And a history of adenomyosis that resulted in a hysterectomy. It was not optional.

Now 3.5 months later the pain is to the point where I feel it all day and if for some reason I have gas, the pain is intense. I have a CT scan scheduled in a few days, but if it gets any worse I'll just go to hospital.

I'm kinda scared because I have a lot of different symptoms and I keep looking for any condition or combo of conditions could cause this. So my questions are 3.

  1. Has anyone here had a similar experience?
  2. Does anyone have any theories or suggestions for what else it could be?
  3. Would it be irresponsible to wait 7 days for the CT vs going to the hospital now?

Here is a list of my symptoms:

- Pain

- Chronic fatigue

- Abnormality in the white blood cells, not leukocyts

- Daily nausea, especially in the morning.

- Severe hormonal fluctuations. It's almost like what I felt like after I've given birth, but more intense and longer lasting

- Crazy acne

- It's very easy for me to feel over full and bloated

- As a consequence I've been eating less because I don't have time for lots of small meals but I haven't lost any weight.

- Bowel issues. I'm constipated if I do nothing. Benefiber causes diarrhea. I've cut back heavily on coffee consumption for the same reason. Just one 12oz cup will send me to the bathroom through out the day.

I'm sorry for the length of the post. Thank you to anyone who takes the time to reply or upvote.

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u/lfIwereaclownfish — 17 hours ago

Does this look suspicious?

20F, 165 cm / 5’5”, 50 kg / 110 lbs, white, no diagnoses, not on any regular medication

I noticed this light bump on my middle finger. When I touch it, I can feel a bulge, it doesn't hurt, but I think it feels different when I press this nail as opposed to others. I don't have that on any other nails. I do have a lot of indents in my thumbs tho, but I think thats probably from picking on my cuticles.

Is this a light bump a sign of something dangerous? I'm scared it might be a sign of something else going on with my body, or that it's dangerous in and of itself, like cancer or something :(

u/cvltpawz — 22 hours ago
Week