r/LiverDisease

I don’t drink. Never smoked. I don’t eat very healthy especially the last 3 years.

I have 3x the normal liver enzymes amount. How do I push for imaging? My mom died of ovarian cancer and her doctor ignored her symptoms that she would tell him about. If he listened, she’d still be here today.

I’m worried for myself now. My doctor thinks it’s stress and bad eating habits but I want to be sure. I do have insurance.

Thanks.

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u/Rnl8866 — 9 days ago

Liver Enzyme’s and Weight Loss

Male 51.

I have always been a beer drinker and been overweight. I see my Dr every year and get my blood work done. For the last few years my ALT has been mildly elevated and my Dr has always told me it is due to fatty liver. A few years back I had high Bilirubin and they did an ultrasound and they mentioned fatty liver. During this time I was also diagnosed with Hasimotos disease. As well as a few other things that overweight people tend to have. Sleep apnea, mildly high cholesterol and blood pressure.
Well this January I found myself at 290 pounds and having a few beers by myself when my wife wasn’t at home. So the next day I contacted my PCP to discuss my weight and GLP medication. We started on it on Feb 15th. My regular check up a blood work were scheduled for April 15. I was looking forward to testing as I had lost 30 pounds at that point. Well, my ALT was up to 85 AST 53 and bilirubin of 1.6. As well my thyroid was way off as well. I was so disappointed as I had been cutting back on alcohol and had lost weight. The only good news is my Blood pressure was 120/80 and cholesterol is back to normal.
Sorry for the long story but if anyone else has a similar story or an idea of what is going on please let me know.

I go back to have another blood test soon so hopefully it doesn’t get worse.

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u/Poppyseedph — 2 days ago

Help my liver values are rising drastically quickly

Over the last few months my labs have been rising and I am completely at loss to what disease I have. I will need a liver biopsy but have a hemangioma.
Anyone had a liver biopsy with that? Also I do not drink nor take any medication. GI is referring me to hepatology. I am 36f with high cholesterol for years though. MRCP normal apart from showing enlarged liver. PSC and PBC and AIH are in the room. I have no IBD as far as I know. I am frightened specifically because they have sharply risen since I have given birth within half a year. They were normal apart from cholesterol.

AST / GOT: 54 U/L (Ref <35)
ALT / GPT: 281 U/L (Ref <35)
GGT: 309 U/L (Ref <38)
Alkalische Phosphatase / AP: 233 U/L (Ref 46–116)
Direktes Bilirubin: <0.3 mg/dL
Kreatinin: 0.66 mg/dL
eGFR: >60 mL/min
Autoimmune / Immunology:
ANA: <1:100 (negative)
AMA: <1:80 (negative)
anti-AMA-M2: negative
anti-LKM: <1:80 (negative)
anti-SLA: negative

Immunoglobulins:
IgG: 0.6 g/L
IgM: 0.91 g/L
IgG1: 5.88 g/L
IgG2: 2.50 g/L
IgG3: 0.13 g/L (low)
IgG4: 0.11 g/L

Virology:
Hepatitis C IgG: negative
Hepatitis E Virus IgG: negative
Hepatitis E Virus IgM: negative
HBs antigen: negative
Blood count:
Leukozyten: 6.0 G/L
Hämoglobin: 13.7 g/dL
Thrombozyten: 278 G/L

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u/DampierE_ — 2 days ago
▲ 5 r/LiverDisease+1 crossposts

Cirrhosis?

My 52 yo husband just stopped drinking 3 months ago after his second round of medical detox. He’s convinced he’s not got cirrhosis because he’s stopped drinking. He won’t go to the doctor but has diarrhea at least once daily and lost about 60 pounds in the months before he quit drinking - maybe 10 more afterward. In detox the last time they told him he had mild pancreatitis. The didn’t treat him there for it. He has itchy skin and hardly sleeps. He eats so much sugar like powdered donuts, candy bars, ice cream etc. Even with the weight loss he has a belly. He won’t go to a doctor except he wants to see a psych to see if he has ADHD because he has racing thoughts. He goes to the gym every day and says he feels fine but less coordinated than usual. He also has really bad shoulder pain sometimes. Are these not all signed of liver damage? Has anyone here had to convince someone to see a Dr for this? Before he quit drinking he drank 10-24 shots of vodka daily for at least 8 years, probably more before we met.

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u/TreeComfortable770 — 4 days ago
▲ 1 r/LiverDisease+1 crossposts

STATS

34F

5’4, 125 lbs currently.

9 weeks pregnant

MEDICATIONS/SUPPLEMENTS

-I’m on Labetalol (100mg split 50mg morning and 50mg evening) for high blood pressure.

-I am also taking Nature Made prenatal vitamins + choline

-Taking doxylamine-pyridoxine (10-10mg—2 pills at bedtime) for my “morning sickness” (just nausea, no vomiting except one time)

SYMPTOMS

-tiredness and nausea from pregnancy. Nothing else. No itchiness or pain.

ABNORMAL BLOODWORK

TUES 4/14 (at hematologist):

Albumin: 4.7 normal ✅

ALK Phos: 144 📈

ALT: 148 📈

AST: 57 📈

THURS 4/16 (at OB):

Albumin: 5 📈 (slightly elevated)

ALK Phos: 134 📉 🚨(decreased but still high)

ALT: 86 📉 🚨(decreased but still high)

AST: normal 29 📉✅

WED 4/29 (at OB):

Albumin: 4.9 normal (slightly decreased) 📉✅

ALK Phos: 193 📈🚨 (increased higher)

ALT: 319 📈 🚨 (increased higher)

AST: 149 📈 🚨 (increased higher)

NEXT STEPS

-I have a liver ultrasound scheduled for tomorrow 5/1

-follow-up bloodwork with hematologist will be on 5/6 (*for context, I’ve been seeing her for a couple years to follow my low WBC at my annual physicals, which began as a peace of mind visit. My WBC have since gone to a “beautiful” range/not concerning at this point)

-I am also being referred to a perinatal center by my OB

QUESTIONS

I am absolutely terrified and have no patience.

-What is the likely cause? Serious liver or gallbladder issues? Something reversible? Everything I see says “could be but unlikely.” The fact I’m pregnant, it says usually liver enzymes would increase later so unlikely. I try to eat healthy, but have pregnancy related food aversions right now so I eat what I can. Some days, I’ll have grain bowls/salads and other days it’s fried chicken and ice cream, for example. Likewise, when I researched if this could be related, it said that my diet wouldn’t cause “that” much of an increase of my liver enzymes. I used to frequent the gym, but have lost motivation with my pregnancy nausea (no vomiting/no HG) and tiredness, so pretty stagnant lately. It also says this wouldn’t cause such an in tease either. I try to stay hydrated but some days are better than others—related? Apparently not likely. I looked up my meds and it says those are unlikely causes too. I’m so frustrated and confused.

-Also, anything I can do to bring these numbers down?

Please let me know if you have any questions for me.

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u/anonweddingguest — 14 days ago

Scarily elevated AST, ALT, ferritin

25F. 220 lbs 5’7. History of hEDS, MCAS, POTS.

My bloodwork last week came back as 807H for Ferritin, 50H % Saturation, 344 AST and 216 ALT. All my other labs were pretty normal. I am a moderate drinker but this bloodwork did come after a week of heavy drinking (law school graduation lol). I am really concerned and am wondering what to do/potential causes.

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u/Wise-Unit-6735 — 3 days ago

this is a new account so please don’t hold that against me.

the tldr is my diabetic middle aged husband didn’t get around to following up with specialist after a fibro scan that shows f3/f4 fibrosis and f/4 steatosis and now he has to wait another two months to see a specialist since the one his primary referred him to longer sees liver patients. i want to know if we should try to find a sooner appointment. the referral said “non emergency“ or “routine” or something. More info below.

my husband is a middle aged type 2 diabetic with non alcoholic fatty liver disease who had a fibro scan last year. his primary doc told him to follow up with GI but didn’t explain that there was any urgency. life happened and he just got around to seeing a GI who I guess no longer deals with liver disease so he was referred out to a different doc.

in the meantime the GI doc went over the fibro scan and his results sound (to me, a layperson) concerning. fibrosis was listed as f3/f4 with steatosis of f4. its my understanding that means he has cirrhosis. he had this scan almost a year ago. he hasn’t had any further imaging of his liver (although he did have an unrelated surgery six months ago and was cleared for that and has had standard blood work for check ups).
but now the soonest he can see the liver specialist is in July, slightly over two months from now. I have been reading about liver disease and I feel this may require more urgency. he hasn’t had a biopsy or anything. Should we try to find somewhere that can take him sooner? or have his primary order tests in the meantime?

thankful for any advice/help.

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u/Anonymouse2987 — 13 days ago

Earlier this month my ALT and AST labs came back elevated for the first time:

110 U/L and 72 U/L respectively.

I had follow up labs yesterday which came back with "Critical test result" in which my values nearly doubled in the span of three weeks:

214 U/L and 123 U/L respectively.

They tested for Hepatitis as well which came back negative (I think, the test result just shows a Fib-4 value of 1.83 rather than an answer).

I don't drink alcohol. I do have high cholesterol- as does nearly everyone in my family, and take Pravastatin. I was a vegetarian for almost a decade until about six weeks ago, and I am 50 years old. I'm not overweight, I exercise and have T1D (LADA).

My endo told me to stop the statin, and wants me to have a fibro scan(?), and see a gastroenterologist.

I was only told this by his nurse on the phone right before their office closed for the day so I didn't get to ask why I need to see a gastro, or what the scan does and if it's worth having.

I first asked in my regular T1D forums, but thought it worth asking here as well.

I wanted to add that I have Lynch syndrome, Castleman's disease, and Ehlers's-Danlos- which causes neuropathy and POTS. I also had surgery for hyperparathyroidism a few years ago, but I have no idea if any or none of these things might have anything to do with elevated liver enzymes.

I have felt somewhat unwell stomach wise for a couple of months (prior to restarting eating meat), but that is not uncommon for me. I've had those issues off and on for years, and never had an elevated liver enzyme result.

I am not jaundice, this was literally just out of the blue.

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u/venerablem0m — 14 days ago

Hi everyone.

I was wondering how everyone has gotten their diagnosis of hepatomegaly and how you have been screened after to check on progress?

I received a ct scan 3/18/26 with the liver coming back at 20cm craniocaudal of right hepatic lobe, and an ultrasound 5/4/26 that said 15.2cm in length.
That seems like a big size discrepancy, the doctors are looking into this but I wanted to see if anyone has had ultrasounds as routine check ups on their liver?

Thank you!

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u/beachvibes007 — 6 days ago

Hi.

I'm 24 years old, female, and I've been struggling with health issues for while but most perplexing is the ALT levels I've seen on bloodwork in the past few months. I've never had any issues with this previously, except for when I was using a lot of NSAIDs in high school. Now, with gastroparesis I don't take any NSAIDs unless I really have to, which is maybe once every month and a half. In early February my Alt level was 43, which they didn't see as an issue and told me to test again in 3 months. They tested it again a week later for my physical and it had gone down to 34, so we thought it was fine. I'm now undergoing allergy testing and they tested my liver values again, which is now 54. I understand that it's not that high, but I am concerned based on the fact that I have no idea what could be causing this. I've never had a single drop of alcohol, I've checked and none of my medications should cause liver issues. I'm normal weight (five foot five and 117 pounds) and none of my other liver numbers are elevated.

Should I follow up with a doctor about this or am I just overthinking things?

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u/Real-General-4351 — 12 days ago

My father got his gall bladder removed back in 2024

At that time his symptoms were severe pain + allergy on his body( pruritus rash )

Can someone plz help

What is this

CBC (Complete Blood Count)

WBC: 8,790 /mm³

RBC: 6.10 ×10⁶ /mm³ (↑)

Hemoglobin: 16.6 g/dL

Hematocrit: 50 %

MCV: 83 fL

MCH: 27 pg

MCHC: 33 g/dL

RDW-CV: 14 %

Platelets: 291,000 /mm³

Differential:

Neutrophils: 76 %

Lymphocytes: 18 % (↓)

Monocytes: 3 %

Eosinophils: 3 %

Absolute counts:

Neutrophils: 6,680 /mm³

Lymphocytes: 1,582 /mm³

Monocytes: 264 /mm³

Eosinophils: 264 /mm³

---

Liver Function Tests (LFTs)

Total Bilirubin: 2.2 mg/dL (↑) (also seen as 1.7 in another report)

ALT (SGPT): 130 U/L (↑) (also 121)

AST (SGOT): 164 U/L (↑)

Alkaline Phosphatase: 44–47 U/L

Gamma GT (GGT): 657 U/L (↑↑)

---

Proteins

Total Protein: 7.5 g/dL

Albumin: 4.8 g/dL

Globulin: 2.7 g/dL

A/G Ratio: 1.8

---

Other

Amylase: 142 U/L (↑)

CRP: 2.0 mg/L (normal)

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u/Proof-Entertainer966 — 13 days ago

I had an MRI and it says I have fatty liver. It doesn’t say a grade or stage or anything. I am worried about it but also worried about change. I’m been doing research and I’m not dumb, I know reduce sugar and alcohol lose some weight…. But I’m wondering for people with a sweet tooth like me what they used as an alternative? I saw Legendary Foods Protein Pastries and Quest proteins snacks could be an alternative.

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u/Mom_of_three_182024 — 11 days ago

I had an ultrasound done on Tuesday and the findings at the top just said “hepatic steatosis” but when I scrolled down further it said this:

Liver:

Echotexture: Coarse

Echogenicity: Increased

Surface contour: Smooth

Lesions: None.

Main portal vein: Patent

My doctor is not back in the office until Monday to review it, but I researched and does coarse echotexture mean fibrosis/cirrhosis??? Wouldn’t that mean that the findings would be more severe than just hepatic steatosis?? Has anyone had similar results? I’m 29F and don’t drink alcohol.

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u/sarahflower22 — 13 days ago

Hi all. I'm 6 months postpartum and I'm in the process of getting diagnosed with AIH, after many years (even pre-pregnancy) of elevated liver enzymes. Had multiple imaging etc - just need the biopsy to confirm, but my GI is all but certain that is what it is. My baby was born with a serious medical condition (unrelated) that will require life long management and hospital visits and, now with my own health issue, I am just so low. I'm looking for real takes on how you live with your autoimmune condition (AIH, PBC, or PSC) and how it impacts your life. Thanks in advance here.

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u/Quirky_Tradition_130 — 12 days ago