Severe iron deficiency anemia with ferritin 8-9, platelets near 500, elevated D-dimer but negative CTA — anyone else experienced this?
Hi everyone. I’m trying to understand what could be causing all of this and whether anyone has gone through something similar.
I’ve had severe iron deficiency anemia for years and have already needed 2 iron infusions in the past 3 years, but I’m still becoming symptomatic and my labs remain abnormal.
Symptoms:
collapsing/fainting
tachycardia (heart rate hit 128)
dizziness/lightheadedness
shortness of breath
exhaustion/weakness
headaches/concussion/head hematoma after passing out
Recent labs:
Hemoglobin: 10.2–10.9
Hematocrit: 33.2
Ferritin: 8–9
Iron: 12
Iron saturation: 2%
TIBC: 564
MCV: 73–77
MCH/MCHC low
RDW: 17
Platelets: 492
D-dimer: 268 (slightly elevated)
Vitamin D: 20.1
Chronic B12 deficiency for years as well
Because of the elevated D-dimer and symptoms, they evaluated me for a pulmonary embolism. I had a CT angiography that was negative, which was reassuring, but I’m still worried because my uncle died from a pulmonary embolism.
I’ve read that severe iron deficiency can sometimes cause reactive thrombocytosis (high platelets), but can it also mildly elevate D-dimer? Has anyone else had:
platelets this high from iron deficiency?
elevated D-dimer with negative scans?
repeated iron infusions but continued deficiency?
could there be an absorption issues?
I know nobody can diagnose me online, but I’d really appreciate hearing from anyone with similar experiences.