r/seroquelmedication

I had anxiety very bad due to a sudden relationship issue and i have General anxiety disorder. I hadnt slept in 3 weeks and my anxiety was super bad and doctor gave me seroquel 25mg cause I cant take lexapro or zoloft as they make me super nauseous and sick. now after 7 days in i considering quitting it as my anxiety is even worse now every morning and i feel better as the day goes on as the meds wear off. I am going to sleep fast but even whilst asleep my heart rate is still super fast and ive only had 2 nights where my heart rate has dropped enough to signify rest.

who has had experience with 1 taking a day off or delaying taking the tablet to have a 3 or 4 drinks of alcohol as have a special event tomorrow and i dont drink often. (like once a month)

second question can i just stop taking it cause im concerned im better off without it now?

I’ve been taking a small dose of seroquel regularly for maybe two years now, I take it at night since I have insomnia and bipolar disorder so it kills two birds with one stone.

I feel as though the past two years I’m just. Never horny anymore, I do not get “wet” down there at all, I never have sexual thoughts anymore, and I absolutely hate it 😭 I’m only 22 so suddenly developing 0 sex drive was pretty jarring

I’m curious if anyone else has struggled with this, I’m just curious if this could’ve happened randomly or if it’s a side effect of this med. Thank you!

Hi. I've been taking 25mg of Seroquel for roughly over 2 years to help me sleep & I recently made the conscious decision to stop taking it. I've been experiencing severe itchiness all over my body since stopping the Seroquel. Is this normal? Thank you.

I’ve been taking seroquel since July of 2025. I currently am taking seroquel at night, 300mgs. In many ways this medication has been a miracle for me. However, come this January when i was increased to 150-200mg i started getting what i think are side effects. Suddenly my body didn’t have the urge to poop anymore and it would be days in between bowel movements. My stools have also been extremely soft, I haven’t had a solid bowel movement in months. The stools are soft and difficult to get out when I actually do go to the bathroom. I went to my gastroenterologist. They have me on a motility medication called motegrity, another chronic constipation med called ibsrela and I’m also taking MiraLAX daily all because of the side effect of chronic constipation and slow transit constipation. I tried fiber supplements to bulk up my stool and it totally back fired on me and made the slow transit even worse. Long story short, the motegrity motility medication stopped working about ten days ago. I keep passing soft blobs of stool but again no urge to defecate just feels like something is stuck. Anyway, has anyone else had these problems on seroquel? It’s like my body decided we will never poop normally again. I was also evaluated by pelvic floor physical therapy multiple times, everything seemed normal to them. My psychiatrist is out of the country until June so I guess I’m stuck like this until he comes back to America.

Hi all. Perhaps it's just me but when I read 'take on an empty stomach' I was thinking "Ha - I NEVER have an empty stomach" and carried on taking them just before my evening meal. I was complaining about being groggy in the morning on the Bipolar sub and someone mentioned not to take XR with food because it causes a 'dump' of the med into your bloodstream and stops it being released slowly like it should be. Holy cow. I took it three hours after and an hour before food this week and the difference is huge. So if you're a plonker like me - stop. :D

so i have been having mental breakdowns about my weight gain cuz of seroquel and i wanted to quit it cold turkey but my psychiatrist told me not to so now ive dropped from 400mg to 200mg and its been like 6 days and now im like cutting quarter of it and soon im gonna drop to 100 cuz now i think ive been taking 175 for a while, what yall recommend to help with the anxiety and does it even help you for anxiety ?

Needing some advice!

I was given quetiapine (seroquel) 25mg by GP for my insomnia, he told me to only take it so often or as needed. I tried it for a few nights, didn’t like it and stopped. After coming home from a trip my insomnia was through the roof, and I fell into the habit of taking the medication every night (stupid, I know). I ended up taking it every night for 7 months, until I recently ran out.

The side effects I’ve experienced from stopping have been terrifying. Keep in mind about 4 weeks ago I experienced drug induced psychosis from weed and and had an awful panic attack. Fast forward to when I stopped taking this medication about 8/9 days ago, by day 4 I had all the same feelings I did when I was high, I even convinced myself I was high again! I had a panic attack and the wildest “psychosis mimicry” symptoms and intense ocd like thought spirals, but it wasn’t a full blown psychosis episode - I could rationalise and see this was my anxiety. Day 5 was the same, day 6 through to now (day 8/9) I’ve been feeling completely out of body and detached, worse then it’s ever felt before. Not to mention the crippling insomnia is back and getting in the way of my studies. I went to bed last night at 10:30pm, tossed and turned with no sleep just to check the time and it was 4:30am.

I went back to my gp and told him all of this, he gave me two options:

- Get back on the 25mg and wait to see a psychiatrist for guidance on tapering down or changing meds, but the wait for that could be ages.

- Continue cold turkey and hope that my symptoms go away in 3-4 weeks.

I don’t know what to do, my family don’t want me going back on the medication, and I don’t necessarily want it either given the withdrawal I had. But so far nothing else is helping me sleep! I wish I never had this medication to begin with. Any advice or similar experiences??

I've been taking 50mg for insomnia for 1.5 years. It was great at first and I was just happy to be able to sleep.

However especially this year I've been feeling my motivation slipping away, I thought it was just laziness or difficulty adjusting because my schedule has been so irregular. It's gotten to the point where I will have deadlines and logically care about them, but emotionally I don't feel anything about it.

Historically I've been driven by not wanting to let others down, which maybe is good or maybe isn't, but suddenly that's not enough anymore and even my logical brain that's telling me I need to do x for the sake of even my own future isn't enough for me to emotionally care.

I've been so confused about it, and it's been so gradual that I don't think I've really been noticing aside from knowing I'm not as motivated. But I made the emotional connection last night and I truly think that's why I'm falling behind on everything.

Has anyone else had this emotional blunting happen super gradually for them? I guess that might be the point if you have bipolar. Do you think seroquel could be the cause?

So hi! I usually take a 150mg XR daily. I switched from upping and downing my dose through the last years I have been Taking it. First of it mainly helps for my anxiety and also bad insomnia. I usually take it an hour before bed time and I have no issues falling asleep, I even sometimes fall asleep my phone in my head while watching a YouTube video (don't judge I like to fall asleep on true crime/paranormal investigation stuff, been doing it for years).

But tonight IDK what's up. Maybe it's the Mountain dew I had on my way back home? But I can legit pass out with my normal dose even after drinking a redbull soooo. Now since I just want to sleep because I have stuff to do I am starting to freak out and took an other dose... Now it's almost 7am here and I am still unable to sleep... I am CLEARLY sedated my head out but my brain just won't shut the switch off for me to fall asleep.

Also FYI when I don't take them, I can sleep but it's the legit worst sleep ever, like light light sleep I'm still conscious but half asleep and it's not really helping.

And I struggle with multiples mental health conditions soooo sleep is EXTREMELY important for this reason.

I don’t lose any weight when I’m awake.

weight loss normally happens during sleep for me. the longer I sleep the more weight I lose.

sero makes me sleep maybe 18 hours or more and one time I checked the scale I went down 2 pounds

for quiatine I found that if I don’t eat during the day and I go to bed. and I wake up more skinny then usual.

I have been on Seroquel 300mg ER (plus 50mg IR as needed) for 10 years. I was prescribed it during a hospitalization and subsequent rehab for alcoholism. I was told I was bipolar but that was likely a misdiagnosis, and my current psych, therapist, family, etc. agree. Had around 20 lb weight gain over time and starting to have some blood sugar issues. Decided to start weaning off 6 months ago after consultation with psych.

My taper went pretty well. I did rush through the end of the taper (50-25-12.5-0 fairly quickly) which I now realize was not the best course of action. A couple weeks after my last dose I had a minor surgery along with a dental procedure all of which worsened my rebound insomnia. I then had massive anxiety which peaked around 3 weeks after my last dose of Seroquel.

Under direction of my psych, I started 25mg of Seroquel IR which did nothing, then 50mg with minimal improvement - he really wanted me to go up to 100mg IR which I finally did. Started sleeping better again and anxiety is improving.

But I just seem to have this constant kind of low level buzz of anxiety that is still there. I can’t figure out if this is my body becoming used to 100 IR after being on 300 ER for so long? Or is it because I restarted the Seroquel and my body is trying to get used to it again?

I am about to leave town and then plan on seeing psych again to talk about restarting the taper, this time with the help of propanolol, hydroxyzine and clonazepam. I have these meds now - tried the propanolol and it helps but makes me tired. Saving the other two for more severe anxiety.

Anyone had this same experience with weaning and then restarting? Also - has anyone had success with using an SSRI as a bridge during/after your taper? My psych mentioned this but I am a bit reluctant.

I have bipolar 2. My psych is constantly trying to get me on Seroquel. I find it makes me a)fat and b) feel like I've been hit by a truck. I haven't taken any meds for a year and have just started again. She wants me on 50mg. I took it once and basically watched TV for the whole next day. I'm taking 12.5 to help with sleep but it doesn't really help I don't think? No more than melatonin / phenergen / Benadryl / chamomile tea anyway?

My psych prescribed me 25mg for sleep as needed. I’d been on seroquel previously during a psychotic episode, don’t remember it doing a lot for me back then though. I took it last night for the first time. This morning I woke up groggy and so so upset. I have work in an hour and Im sitting in my bed rocking back and forth and sobbing and pulling at my hair. I feel like I want to claw my veins out of my wrists. I’m generally pretty stable these days, I haven’t wanted to hurt myself this bad in years. Is this something seroquel can cause?

I tapered from 300mg to 50mg in a week and I feel so much more in control, not diagnosed schizophrenic or bi polar. just major depressive disorder and anxiety disorder, it’s the right amount to put me to sleep and not feel tired in the morning. I’m gonna start working out as well and get employed soon, this is so great I’m greatful for tapering. Never cold turkey seroquel it is an absolute nightmare that I never wanna go thru again.

I’ve been trying higher doses 50-75ng and i don’t know if it’s worth trying 100mg for anxiety (what it was prescribed for) or if it’s just going to make me drowsy and I can call it that this med isn’t going to help me except for making me sleepy.

Hey guys, I'm really new here, new to posting on Reddit at least but I'm looking for some advice. I'm currently in limbo at my job, my union is NOT being helpful thus far in even securing an answer to whether im fired or not but the company wasted no time in cutting off my benefits.

I have 11 50 mg pills left and i'm so worried im going to have to just quit cold turkey if I don't get my job back along with my insurance. I've been on Seroquel, specifically the generic, for about 7 years or so and while thankfully I seem to be on the fairly low side of things I'm so, so worried about withdrawals. I was given this mostly as a sleep aid because my job required me to switch shifts every week (night shift to afternoons to mornings), and I was never able to stay asleep but this helped me stay asleep for longer than 2 hours. Could i potentially just cut my pills in half and hopefully adjust well enough to get off it entirely or are withdrawls for 50 mg not as severe as the higher dosages? Also, please forgive me if this is all over the place, its 2 in the morning and I'm too anxious from everything going on right now. Thank you in advance! ❤️

I've been on 100mg of Seroquel for 6 weeks, I ran out for a week and had horrific dizziness and withdrawal symptoms. I'm back on for 3 days and the dizziness is getting worse, I told my doctor and he said to stick with it but today it was severely worse. Has anyone reacted similarly?

I’ve heard these are faster acting and have a longer duration. I really want to get off the seroquel I was put on (back when I barely had a sleep problem, was in a hospital setting I found it hard to get good sleep in , just was naive and told it wasn’t addictive and not like a z drug. Since then I’ve completely become dependant physically to sleep (can’t without at all, even nap), and also it doesn’t work anywhere near as effectively - takes hours sometimes to fall asleep, with eating involved (not good) and my dr has added Ativan and zolpidem (stilnox in Aus where I am) ambien other places.

Is this often or prescribed widely? Thinking of bringing up to my doctor/ psychiatrist ..

Any input thank you in advance 🙏🤍

okay this is a bit NSFW im not going full graphic here but still fair warning. a BIG side effect i dealt/deal with is crying/ breaking down after an orgasm I later went on to find out it can be common on these meds because of the way they interact with the brain and it's nureons and such anyway I am a pretty sexual person and I found that with sex this doesn't happen like after I don't cry or breakdown I assume it bc im so focused on the fact of who I am with it changes it a bit around however my gf and I have never so I do things alone and I say probably no later than a minute after the big O I can just feel myself wanting to just sob and breakdown i just try to tell my self out loud "nope were not doing this do not do it youre find no dont do it" as if training an animal i have found if I do let the breakdown happen its not a normal cry it out its full blown panic attack sobbing cant breathe heavily suicidal thoughts and feelings that I can not calm down. now I know this is personal but has anyone else experienced this or has a tips or advice?

Side effects Quetiapine

I used to have a high heart rate because of Quetiapine (after taking 300 at once) even vomited once because of it. Splitting dosage helped, but before this, I had this weird episode. I took 300 and went to sleep immediately. I assume my heart rate went up. I got up to go to the bathroom, I remember getting up and going there, using it, the next thing I remember sitting on the floor by the wall barely conscious and my girlfriend staying over me and me bagging for help and her helping me get up a lay down. I was barely able to talk and felt horrible, but then fell asleep immediately and was fine after. She told me she saw me in the bathroom, washing my hands, and seemed very sleepy. Then I just leaned on the faucet with my head for a bit very weirdly and sat on the floor afterward.

Now I split the dosage, and everything seems fine, but it was so weird and scary - why did I barely remember anything, and what was that? Does anyone know what it could be?

I also suffered and still sometimes suffer from being shaky and physically very unstable from it