Hello, for some days i see on tiktok many videos talking about aspirine, reducing prolactin, boosting things in body, but i have one question, if you go to the gym and you take aspirine or other nsaid, how you can grow your muscle if the inflamation is stopped?

Hi 24 m 118 pounds. Anyone had neck injury then develop pots? Year ago was 145 lean in great shape working 50 hours a week.

Diagnosed with pots a week ago after waiting 13 months for appointment.

Question is, Anyone had pots caused by a neck injury?

I believe a nerve entrapment or neck injury of some sort is what’s causing all of this but it seems impossible to convince a doctor they act like they’ve never heard of this before.

I believe I hurt my neck and possibly some nerve damage etc then all these health issues started originally very extreme rapid weight loss couldn’t swallow dysautonmia symptoms neck and back and stomach obliques got so tight could barely turn my neck left and right. Left side of neck inflamed etc etc I won’t over rant but a bunch of neurological and physical symptoms/ issues including bad blood pooling in feet and red hands and feet worsening veins etc etc I could go on.

As I’ve stretched and corrected my posture and taken supplements are good diet etc I have improved massively over past year but pots symptoms and pressure on stomach from muscles still biggest issue.

Has anyone had a similar experience? Anyone had same experience and fixed it and all issues went away?

Thanks for any info!

I wanted to share a successful recovery protocol for Patella Luxation (dislocation of the knee) following a traumatic injury. After a formal veterinary diagnosis, I bypassed the suggested "Salmon DNA" injections due to the lack of long-term data on foreign DNA integration and instead opted for a more biologically harmonious route.

The Protocol:

• 1. Bio-Mimetic Viscosupplementation: We used non-crosslinked Hyaluronic Acid (HA) injections. It is vital to use non-crosslinked HA as it directly mimics the body’s natural synovial fluid, providing immediate lubrication and shock absorption without synthetic additives.

• 2. Photobiomodulation (NIR Red Light): I applied Near-Infrared (NIR) light therapy to the joint for three consecutive days per week (followed by four days of rest to allow for cellular signaling and repair). We maintained this for a two-week cycle.

• 3. Targeted Nutritional Support: I integrated Wheat Germ Oil into her diet. Rich in Vitamin E and bioactive lipids, it acted as an internal catalyst for accelerated connective tissue repair.

• 4. Mechanical Support: We utilised a high-quality patella brace (by Osha) to maintain alignment during the initial healing phase.

The Result:

Within just two weeks, my dog made a full recovery. Although I limited her physical activity to walking only at that time, she is back to her high-energy baseline with zero instability, proving that a sovereign, integrative approach to joint health can be a viable and often superior alternative to invasive surgery.

It’s been 2 months now since the initial diagnosis and she’s back to jumping and doing her agility games and I plan on getting her a second HA shot in the joint areas to solidify the gains made.

For those of you with dogs who may have suffered from this problem, I wanted to share this protocol with you.

So I've been really burned out at work lately. Both mental fatigue and physical fatigue. I obviously need to keep working bills and rent. But it is affecting my personal life at home where I just don't want to do anything besides stay home on my days off all day long and when I come home from work I do absolutely nothing besides laying in bed until dinner time eat and the main bed until bedtime. It's been like this for months I've lost track but I have a lot to do a lot to change I just can't seem to get out of this funk

Hello,

I've seen comments in here before about the health benefits of beets. Beets are top of the list for me in terms of both nutrition (healthy nitrates, betalains) and value. Plus, I happen to enjoy the taste, and they're quite filling. So I've been eating about 1 beetroot every day.

However, I've just found out that beetroots accumulate heavy metals like lead and cadmium at a higher rate than many other vegetables - even organic ones, since the problem lies in the soil. This is also a problem for turmeric and ginger.

My question is, does anyone know of a source for lab-tested beetroots? I am less interested in powders/supplements since these tend to get expensive, and I enjoy cooking with the whole vegetable. I am only worried about this since I eat beets daily, and due to the health benefits I am reluctant to eat it less frequently.

Let me know where you source your heavy-metal free beets!

I love playing soccer, but the only session slot we have to book in our local soccer field is at 11 PM until 12 AM. I wake up at 9 AM for work. And the earliest time I can go to sleep is 1 AM, but I find it really hard to fall asleep. I suspect this is because of the intense cardio. Is there some protocol for decompressing and calming my body down so I can fall asleep easier?

Thanks

Any research success or accelerated healing with wolverine stack with ghku after any type of amputation. Research subject is two weeks out from amputation is 37 yrs old . Amputation was due to frostbite that a hospital ended up letting get infected. No circulation issues. Thanks

I feel like i am so dopamine depleted that I can at most scroll social media

What's the primary reason athletes, or even performance-oriented hobbyists, begin to decline performance-wise in their 30s assuming they were completely dialed in during their 20s? I know many people have made the best athletic progress of their lives into their 30s and beyond, but peak performance and recovery capacity seems to take a hit for top-performers compared to the previous decade. Is it primarily down to testosterone, wear-and-tear on joints or ligaments, or something else entirely?

Hi everyone, I’m hoping to get some insight because I feel really stuck.

I’m a 22-year-old female and was very active prior to getting sick in February (possibly a bad cold or COVID). Before that, I was lifting 5–6x/week, doing StairMaster at levels 8–9 about 4x/week, and consistently hitting 10k+ steps daily. I have a decent amount of muscle mass and diet is good.

Since getting sick, my exercise tolerance has significantly declined. I’ve been slowly trying to return to the gym, but progress has been very slow and inconsistent:

•	My lifts are much weaker than before

•	My cardio capacity has dropped noticeably

•	I can usually only get through \~3–4 exercises before feeling unwell

The most concerning part is that near the end of workouts I experience:

•	Left arm tightness

•	Significant dizziness (especially when standing up)

•	Shortness of breath

I do try to fuel beforehand (banana with honey + salt, electrolytes), so I don’t think it’s purely low energy.

I’ve had basic labs done and everything came back “normal,” but these symptoms are still happening and are limiting me a lot.

Has anyone experienced something similar after a viral illness? Could this be something like post-viral fatigue, dysautonomia, or something cardiac-related?

I’d really appreciate any insight or suggestions on what to look into next.

Thank you

Not sure if this is common knowledge but I genuinely had no idea until recently, so sharing in case it helps anyone.

Most of us assume that when our doctor orders bloodwork, we're getting a thorough picture of our health. I assumed this for years. Turns out that's not really how it works.

Here's what a standard annual physical typically includes:

— Complete Blood Count (checks for anemia, infection)

— Basic Metabolic Panel (kidney function, blood sugar, electrolytes)

— Lipid panel (total cholesterol, HDL, LDL, triglycerides)

— TSH (one thyroid marker)

— Sometimes glucose or HbA1c

That's roughly 10–15 data points. And they're designed to catch serious problems that have already developed — not to understand how your body is actually functioning day to day.

Here's what I didn't know existed until a few months ago:

There are services now (not through your GP, you find them independently) that run 100+ biomarkers in a single blood draw. The difference is significant. They cover things like:

— Advanced thyroid panel (not just TSH — Free T3, Free T4, thyroid antibodies)

— Full hormone panel (testosterone, estrogen, progesterone, DHEA, cortisol)

— Detailed cardiovascular markers (Lp(a), ApoB, homocysteine — things that predict heart risk even when standard cholesterol looks fine)

— Inflammation markers (hsCRP, ESR)

— Nutrient status (vitamin D, B12, folate, ferritin, magnesium — actual levels not just "in range")

— Metabolic health (fasting insulin, HbA1c, uric acid)

— Liver and kidney function in depth

The difference isn't just the number of tests. It's the interpretation. My GP would hand me a printout and say "everything looks normal." The service I used gave me a detailed breakdown of every marker — what it means, where mine sat, and a step-by-step plan for what to actually do about it. I could also message a clinical team with questions and get a real answer within 24 hours.

I had markers that were technically "in range" but sitting at the low end — cortisol, ferritin, vitamin D — that explained years of fatigue and brain fog. My GP had never flagged any of them.

The one I used costs $199 for the year .The labs are CLIA-certified, the same standard used by hospitals, and the clinical team that reviews your results are actual physicians.

I'm not saying don't trust your doctor. They're essential and I still see mine. But for understanding how your body is functioning on a deeper level — especially if you've ever felt off and been told everything is fine — the gap between what a standard panel catches and what comprehensive testing reveals is genuinely eye-opening.

Thanks for reading .

Hey everyone,

I could really use some advice based on Andrew Huberman protocols or anything science-based.

My situation:

I fall asleep easily around 10 PM

I wake up and get sunlight exposure in the morning

I exercise regularly

ano screen light 1 to 2 hour before sleep

So overall, I feel like I’m doing most things “right.”

The problem:

I keep waking up around 3 AM, and after that my sleep becomes fragmented.

But the main issue is my dreams — they are extremely vivid and detailed, to the point where I wake up feeling like my brain didn’t rest at all.

It honestly feels like I’ve been mentally active all night.

What I’ve tried:

Magnesium

GABA supplements

But the intense dreaming is still there.

What I’m looking for:

Ways to reduce dream intensity / overactive REM?

Any Huberman-style protocols that specifically address this?

Could this be related to stress, cortisol timing, or something else?

Would really appreciate any insights

Some of you are already running BPC-157, GH secretagogues, or some version of a nootropic stack. The anecdotal evidence is everywhere. The peer-reviewed data is almost nowhere.

That's the actual problem. Not whether these compounds work - plenty of people believe they do - but that rigorous, reproducible, open-access science barely exists for most of them. Without it, dosing is guesswork, mechanisms are unclear, and the gray market keeps operating in a vacuum.

Brian Armstrong flagged this directly. He listed next-gen human enhancement across muscle, cognition, and mood as one of the most underinvested areas in frontier biology: https://x.com/brian_armstrong/status/2040479960683417804?s=20

ResearchHub Foundation took that seriously and opened two funding opportunities for researchers ready to generate real data.

1. Peptides for Human Health: rigorous research into peptide therapeutics across metabolism, tissue repair, neuroregeneration, aging, and body composition. BPC-157, TB-500, GLP-1 agonists, growth hormone secretagogues, and beyond.
2. Next-Gen Human Enhancement - Muscle, Cognition, and Mood: for researchers going beyond GLP-1s into myostatin inhibitors, BDNF mimetics, psychoplastogens, mitochondrial enhancers like MOTS-c and urolithin A, and gut-brain modulators.

Both are fully open-access and open to crowdfunding. Proposals are already coming in. Everything gets published regardless of outcome.

If you're a researcher or know one working in this space, this is worth sharing!

Huberman's work on neuroplasticity explains the mechanism: errors release epinephrine, acetylcholine, and dopamine, which tag neural circuits for rewiring during sleep. The cerebellum fires correction signals, the basal ganglia reinforces what works... but this only happens if the error is detectable.

If you can't clearly see that what you did didn't work, none of this fires.

This has been discussed across a bunch of huberman lab episodes, especially #7 (Using Failures, Movement & Balance to Learn Faster) and the skill learning episode. Also comes up in the Josh Waitzkin episode which is one of the best ones if you haven't seen it.

The Macnamara et al. 2014 meta-analysis found that deliberate practice explains 26% of performance in games, 21% in music, 18% in sports, 4% in education, and less than 1% in professions. The study found, but did not explain why, for example, that practice in chess matters 26x more than practice in management.

Macnamara's team actually noticed the pattern and proposed "task predictability" as a moderator, but they treated it as a label, not a measurable variable. They never defined it with a rubric, never scored domains quantitatively, never connected it to a mechanism. The closest thing in the literature is probably "task complexity" but that's vague and doesn't predict the rank order. Chess is more complex than darts but practice explains more in games than in sports...

We scored each domain on a single variable - how clearly and quickly you can see whether what you did worked and plotted it against the published data. The correlation is almost perfect (93% predictive accuracy). Games have the clearest feedback and the highest practice payoff. Professions have the noisiest feedback and practice explains almost nothing.

The error-plasticity mechanism explains why. In high-feedback domains, your cerebellum gets a clean error signal every few seconds. Dopamine spikes are frequent and precisely timed. Plasticity runs at full speed. In low-feedback domains there's no error to detect, no correction signal fires, and the plasticity machinery just idles.

The same variable also predicts why indigenous cultures on five continents independently calibrated psychedelic ceremony durations to match drug effect durations at near-perfect accuracy. And why brazilian jiu-jitsu has advanced faster in 30 years than most martial arts did in centuries. Completely different domains, same principle: the clearer the feedback, the faster any system learns.

Curious if anyone has seen Huberman discuss why practice effectiveness varies across domains? Or if anyone has any research/literature on that. I haven't found an episode where he addresses the cross-domain gap directly.