r/mescaline

Had to cut this piece cause its roots were started to rot due to absolute stupidity of mind, absolutely had no intention to cut it, especially before summer. Now i am waiting for it callus to repot but cant stop thinking if it's the time. Long time psychedelic user with a lot of experience with 50+ shrooms to all the way to multiple ayahuascas but never did mescaline before, yet i want it to be a strong trip when i do. What you guys think? It weighs about 2kgs. All helps appreciated. Thank you!

I've been doing some research on the cactus alkaloids, specifically the class of tetrahydroisoquinilones (TIQ). It looks like Pellotine is active at 5-HT1, HT6 and HT7 receptors. The 5-HT6 and HT7 receptors are known to promote synaptogenesis (formation of new brain synapses) which also happens via 5-HT2a (the more well-known receptor associated with psychedelics). This study concluded that Pellotine has relaxing effects.

There are several TIQ alkaloids with as yet unknown properties and cactus often contains the stimulant Hordenine (a phenethylamine-type alkaloid). It has dopaminergic (D2) activity, increases noradrenaline (NRI) and temporarily reduces MAO-B activity.

On a different note, I'd like to clarify that people with higher levels of the enzyme ALDH will require larger doses of mescaline. Conversely, people with naturally low ALDH levels will find smaller doses to be active. Many things can influence the level and activity of ALDH.

I originally used a standardised extract of pomegranate (as capsules) but a glass or 2 of juice will work for most people (as this poster reports). There's several ALDH inhibitors to choose from...but it's just as important to avoid things that increase ALDH. Here's a fairly comprehensive list:

• cruciferous vegetables (eg broccoli, broccoli sprouts)
• supplements containing taurine, lipoic acid (ALA), sulforaphane, vitamin B5, vitamin B6, N-acetylcysteine (NAC), garlic, turmeric/curcumin, glucosamine, carnosine, arginine, ornithine, resveratrol, dihydromyricetin, ALCAR, CoQ10
• vegetable (seed, nut) oils and omega 3/fish oils (omega fats get broken-down into aldehydes which will induce ALDH activity over time; eg acrolein, malondialdehyde)

I posted a while ago about having done my first CIELO tek with san pedro and not having much success. Folks suggested that they were likely weak plants and to try using fumaric acid (I'd only used citric acid). You can see the post here https://www.reddit.com/r/mescaline/s/S94g0tXOsH

I had the ethyl acetate mix spread across three jars and tried fumaric acid and magnetic stirring on all of them. I think perhaps I put too much fumaric acid in one and got what looked like it was just fumaric acid back. Like white clumps that didn't look like crystals. The clumps aren't pictured but what I got out of one jar is on the right.

The left is what I scraped from the sides of that jar, and foolishly put it with the first stuff initially before I noticed a slight colour and texture difference. So the left container has a bit of the contents of the right container in it as well unfortunately.

ANYWAY. What do y'all think? Is the right likely excess fumaric acid? Is it possible that it's mesc in the left? And if it is, would it bad that there's some of the suspected fumaric acid in it? Like if I ingested it anyway would that be bad? It's such a small amount it's probably not worth it anyway but thought I'd ask 🤷

if anyone could tell me the best way to extract the mescaline that would be very much appreciated

hi all, I’m planning a ceremony in a month with these guys. what’s the best way to store them? indoors / outdoors. sun / non sun?

thanks for your tips

How did i made it :

I froze it for 12 hours

Then boiled it for 3 times, each time with different water ( I changed the water 3 times ) in the fourth round i mixed all waters together , each round 3 hours

The TRIP :

3 friends, dosed at 11:00am

One friend threw up at 11:40

We went to the forest

The kick in started at 12:15 pm at the bus

1:10 pm … at the forest, can’t believe what im seeing and hearing, i was in heaven literally, no hallucination ( just ultra 8K quality visuals and 8k sound system in my head)

Peak lasted for 7:00pm

The peak :

Wisdom

Freedom and soul cleaning

Love and joy with friends

Laughed till my cheeks hurt

Closed eyes geometry patterns

Unbelievable realistic existence

Unbelievable nature beauty

My head is empty verrry much and it teached me controlling my thoughts and anxiety and overthinking , its like sanpedro told me just learn to shut up and just observe

I felt like i wanna live here forever , i felt empathy for the people who don’t even know what this life and nature have

10/10 trip and everything was extremely perfect and peaceful

Things i did that I believe made my trip great :

RESPECT, I respected the grandfather san pedro so much, I asked for help healing and love , I apologized to it even when cutting

I respected the forest and asked it to welcome me if im wanted and protect my peace and show me the beauty and I believe it worked … and thanked mother earth in the end of the trip for that experience and existence.

Intention is so important as always .

Flash point for EA is 24f degrees.

Ref 1 Wiki

Ref 2

Ref 3

I used 2.50 grams of citric acid because I used 50 grams of cactus powder, this is my first time doing this just want to make sure I got this right. 1st photo before second photo after

For reference I’m on the lighter side about 120 and the cutting would be about 8 inches

Hey guys, I came across this crested/variegated cactus and I’m trying to figure out what it actually is.

My guess is that it’s Trichocereus macrogonus, but I’m not totally sure.
Do you guys think that ID makes sense, or does it look more like some other Trichocereus/Echinopsis type?

Also, if it really is macrogonus, what’s the general consensus on mescaline content for this species?
I know potency can vary a lot depending on clone, growing conditions, stress, age, variegation, cresting, etc., so I’m not expecting an exact number — just wondering where it roughly stands compared to pachanoi / peruvianus / bridgesii.

Would appreciate any opinions. Thanks.