r/Semaglutide

Forever thankful for this medication.
🔥 Hot ▲ 268 r/Semaglutide

Forever thankful for this medication.

I truly don’t know how to put into words that this medication gave me my life back. I am now able to confidently live my life, go shopping where I want, and feel good in my own body for the first time ever.

Started 2024

SW: 279

CW: 174

u/Maleficent_Check5579 — 6 hours ago
🔥 Hot ▲ 71 r/Semaglutide

60lbs down!

Down 60lbs and finally finding myself again after having kids. The weight packed on with my first pregnancy, and would not come off. This gave me my confidence and life back.

I started in March 2024 and it took a little over a year to lose 60lbs. I have not worked out consistently or dieted, just drinking and eating less. I have found that I prefer healthier options and naturally reach for more protein.

5’8

SW: 204

CW: 145

u/Barks_and_Bubbles — 5 hours ago
🔥 Hot ▲ 158 r/Semaglutide

6 months progress

Started 4th October 2025. Sw 96.2 kg CW 77.6kg GW 65kg (maybe?) I am still only taking 1mg (pen) I absolutely love this drug so much. It has dampened the food noise so much I can actually concentrate on other things. I swear it's improved my anxiety.

Worth it!

u/RoutineActivity9536 — 9 hours ago
🔥 Hot ▲ 125 r/Semaglutide

Study: GLP‑1 Drugs May Fight Addiction Across Every Major Substance

A recent study of over 600,000 people found that GLP-1 drugs may significantly help fight addiction across every major substance category, including alcohol, nicotine, and opioids.

I thought this was fascinating – anyone here have first hand experience?

Important to note: GLP-1 medications aren’t approved for addiction today, but (as Dr. Al-Aly writes) “if additional trials confirm that they effectively curb cravings across addictive substances, these drugs could begin to close one of the most consequential treatment gaps in medicine.”

Full article, no paywall ofc.

u/Bash1991 — 17 hours ago

Encouragement

Hello.. so I'm starting this journey tomorrow and I'm terrified. I've done a lot of research and told myself I wouldn't ever take these... and here I am. After researching I feel like there's more benefits then just weight loss. I guess I could really just use encouragement and maybe your expierence the first injection.. thank you

reddit.com
u/decayd81 — 7 hours ago
▲ 3 r/AskDocs+1 crossposts

Intense GI upset.

Female / 34 / 5’7” / 165

Non smoking. Maybe have a drink once every few months.

Adderall 20mg x2 a day/ as needed

Wellbutrin 150mg

Propanol 10mg x2 a day to help with migraines

Zoloft 50mg

Stool softeners at least a few times a week.

I’ve been on Wegovy since January 2026 and have done really well. Started at 195 down to 165lb.

Only ongoing issues are constipation and frequent headaches (I do have a history of migraines).

Last week I had a sudden, severe episode — woke up around 5am with upper stomach pain and sulfur burps (which I had once before and the same thing happened), then started vomiting and had nonstop liquid diarrhea for about 18 hours. Completely bedridden and had to have my husband come home to help with the kids, which I have NEVER had to do except once before for the SAME thing.

Day 2: Weak, some stomach pain, still sulfur burps + non stop diarrhea- did eventually take Imodium and got some relief. No throwing up after the first 18 hours

Day 3: Migraine, mostly back to normal

Day 4: Totally normal.

This same exact thing happened once in mid-February too, just as bad. No unusual food before either time.

I have a PCP appointment in two weeks.

I know sulfur burps can be normal for wegovy, but for me it’s a sign I’m about to be real sick for 24-48 hours. I’ve never saw

It’s honestly awful, but the medication has worked really well otherwise, so I’m trying to figure out if this is my “normal” or something to be concerned about.

For quick reference I’ve taken 13 injections

4 were .25

The rest have been .50

Both episodes have been on .5

Oddly enough both times have been on a TUESDAY, my injection day is FRIDAY.

I was hoping to go up to the next level after this month, but now I’m guessing I need to stay in .5 for a bit ? Thoughts?

reddit.com
u/Sneakysassy21 — 1 day ago
▲ 10 r/TDAHFrance+1 crossposts

TDAH et perte de poids / semaglutide

Bonjour à tous, je suis une Femme TDAH de 34 ans , sous medikinet, et je n'arrive plus à perdre de poids. J'ai lu plusieurs études qui mentionnaient que les semaglutides pouvaient avoir un effet bénéfiques pour les TDAH avec la relation à la nourriture et je cherche un médecin à Paris qui pourrait me recevoir et me prescrire du Wegovy ou Ozempic. Je cherche des personnes avec des expériences similaires, merci .

reddit.com
u/No-Satisfaction9131 — 17 hours ago

I lost weight without much effort.

Leaning into healthier choices and smaller portion sizes required little attention. Despite an exceptionally small dose, I still lost about 3.7% of my body mass. I do not know if my muscle mass decreased. I do know that the amount I am able to lift has either stayed the same or increased since I began the experiment.

I drank less. Usually I have a few glasses of wine a week. In the last month without trying to change my alcohol intake I decreased the amount I usually drink by half.

u/ExoticCollar3594 — 20 hours ago

Gym routine

Hi looking for recommendations on what ppl do at the gym to help tone up their body after weightloss. Lost 60lbs on medicine since September 2025, now at 150lbs cw and starting to go back to the gym and have been doing off and on cardio/long walks a few times a week. My most stubborn fat is around my hips/back/stomach and my thighs are significantly smaller but need some toning.

reddit.com
u/Scary_Air_8582 — 7 hours ago

Bad side effects, has anyone delayed 0.25 dosage

I’ve been super sick from what I think was eating back to back protein bars yesterday? Super bloated stomach, sulphur burps, uncomfortable. Today my stomach still feels bad so I’ve been having trouble eating things so I’ve been eating little bits of protein slowly.

This Sunday is my 3rd dose of 0.25. I seem to be a very strong responder. I’ve lost 3 pounds so far. I’m considering delaying the 3rd injection a day or two? Has anyone done this? I’ll be asking my pharmacist but wondering if this helped anyone in the past.

reddit.com
u/bailsandsails — 11 hours ago

Changes in private insurance coverage for GLP-1s

The popularity of weight loss drugs has caught insurers off guard. They've responded by tightening eligibility, adding administrative hurdles, or dropping coverage altogether. An analysis by GoodRx found that insurance coverage became "more restrictive" in 2026. More from Business Insider's Allie Kelly here: https://www.businessinsider.com/lost-100-pounds-zepbound-insurance-denials-ozempic-cancer-2026-4

u/EdithHonan — 13 hours ago

Do you change your dose based on hunger or just the scale?

There are times appetite comes back a bit but weight is still trending down.

That’s where I get unsure whether to increase or just leave things alone. Hunger alone doesn’t seem like the best signal, but it’s hard to ignore.

Trying to figure out which one matters more.

reddit.com
u/Maasbreesos — 12 hours ago

Is 3 pounds in 3 weeks slow loss?

I’m on 0.2MG semaglutide (switching to 0.4MG tomorrow) and I am 3 pounds down in 21 days. Is this slow for someone who weighs 312 pounds and is 5’8?

reddit.com
u/fohtvuub — 14 hours ago
▲ 4 r/Semaglutide+1 crossposts

Week 5

Hey guys, I just had my 5th shot last night at .35mg. Everything seems to be going good with snacking and food noise & I maybe eat once a day, but when I do it’s like I can’t stop… I know this stuff is supposed to help you feel full faster/longer and I am just not seeing that. My weight also keeps fluctuating. Started at 163lbs, last week I was at 156lbs and I weighed myself this morning and I am at 161. Is this normal?? I’m feeling a bit discouraged. I don’t know if it’s too early to notice a change or what, but the weight fluctuating is just super confusing.

reddit.com
u/ChocolateOk6361 — 19 hours ago

Anyone else stop progress on their period?

I fear the cravings and water weight are no match for my small to medium dose. Does anyone feel different on it during that time, and how did you feel after? Back to business?

reddit.com
u/Ok-Computer-7 — 19 hours ago
▲ 4 r/Semaglutide+1 crossposts

Please Help

I have been on ozempic for 2 years for insulin resistant PCOS. I titrated up very slowly to avoid getting sick and negate side effects. It’s been pretty smooth sailing so far. I’ve only felt sick once or twice i went up a dose too quickly. I have been on 1.75 for over 2 months now and I am experiencing gross sulfur burps and gas suddenly within the past week and a half. My diet hasn’t changed, I don’t eat fried or fatty foods often. It’s making me not want to eat and miserable, I’m in Australia, i dont have pepto bismal, i’ve tried gaviscon and it hasn’t helped. Idk whats going on. Any remedies that have helped would be greatly appreciated

reddit.com
u/lexilou_dimplington — 23 hours ago

First timer on sema!

hi everyone. Just looking for some input. I just had my 3rd shot of sema on a .22mg dose. im also just starting my period and was curious to know if the shot has affected anyones monthly and when did the medication really start kicking in for you. :) thanks everyone. little background, im a mom of 4, im about 5'1" and SW is 236. I have lost 4 pounds but gained one back(not sure if its because of my period).

reddit.com
u/coffeebeansnorter29 — 16 hours ago
Week