Hi all
I have discontinued valdoxan as of 2 nights ago.
At the moment I have felt absolutely fine except not sleeping very well.
I just wanted to hear some success stories about people who stopped and eventually slept again, to encourage myself it’s possible. Because I think my not sleeping is partly the anxiety about not sleeping.
No need to share any disaster stories as I am more than aware of all of those haha
Hi Guys,
Im from Germany and been suffering from anxiety and some Kind of Depression since 2014. Im currently on Escitalopram 15mg (Citalopram since 2014 then switched to Escitalopram in 2021) and since Nov 2025 on Agomelatin/valdoxan 25 mg - i Upped The Dose to 50 mg 29 days Ago.
Im a bit desperate because my Anxiety is still going strong - and I only read Bad Reviews about valdoxan - Like it doesnt do anything for anxiety.
The only up side of these 4 Weeks is lifting up my anhedonia. Which is nice to feel some form of Joy.
Is there a recommendation you Guys can give me. Should I wait Till week 6 for the anxiety to get better ? What are the alternatives in my Case ? My Psychiatrist told be about bupoprion but im Afraid it will up my anxiety Even more.
I would be thankful for any advice. PS: yes I ve been in Therapy Couple times but im only allowed in September to Go again
Hi guys
I’ve been on valdoxan for 3 weeks now (25mg) and so far have 0 improvement regarding anxiety. Leaving the house I’m still getting all physical reactions like prior to the medication. This is my second medication that I have tried and am scared that this one won’t work either. At what point should I expect to start feeling better?
Hi all. I’d love to hear some success stories from those who’ve taken Agomelatine. I’ve been on 37.5mg for the past few weeks, gradually increased from 12.5mg, but I’m still experiencing occasional flare-ups, anxiety, and mood swings.
For those who responded well to it, when did you start noticing things getting better or more stable? It felt better for the first few weeks but the depression slowly came back.
So first of all I want to make clear that I'm not upping my dosage by myself, my psychiatrist upped it!
For context : I've been taking 50mg (two tablets) of Valdoxan for about 2 years now, along with:
- 400mg quetiapine
- 12,5mg Tercian (to help me fall asleep and not have mild panic attacks when I go to bed)
- 36mg Concerta in the morning for my ADHD
- Drosperidone (contraception pill)
I fell back into depression and my psychiatrist upped my Valdoxan to 75mg (by taking three 25mg tablets instead of two), but I can't find ANYTHING anywhere about anyone taking more than 50mg. Even the information leaflet doesn't mention taking three tablets.
I guess that if he prescribed it to me, it's that it's okay, but it makes me really nervous to know that 75mg isn't a standard dosage at all - especially given that I take a lot of different meds, so I'm worried about the interactions too.
I'll ask at the pharmacy when I go tomorrow, but in the meantime I wanted to ask: is anyone of you taking 75mg? How is it? Do you have any side effects? I'm so nervous 😭
I know the title is weird but hear me out.
I’ve been taking agomelatine (Domion brand) for 19 days now.
Every time I take it, without fail, I start to feel a really warm liquidy sensation in my upper left abdomen and chest/throat within thirty minutes of taking the dose.
It’s almost a sickly burning sensation.
Anyone else? Does it go away?
It’s not terribly uncomfortable but I’d really rather not have it because it makes me anxious.