r/TRT_females

I was worried about the effects to skin and hair based off of what I've read. I do have a few pimples. But other than that, with increased oil production, I have this dewyness. My skin also looks and feels firmer, and my hair feels thicker. Anyone else have this happen? I hope it lasts!

I'm on 10mgs 2x split weekly. I've only injected twice now. I'm wondering if this is placebo or if my libido could actually come back this quick? Before I took T I hadn't even thought about sex for a year!! It was crazy, I used to LOVE sex!

So what do you all think?

I’ve had low t for a long time now. But I needed to get my thyroid leveled out first. My doc started me at .25ml 2x a month is this normal dosing. Google says this is high and I’m freaking out of course I looked at google after my first shot! I’m pretty scared to be honest if you didn’t get that from my title can anyone give me any insight or reassurance? I’m 36 female athlete hashimoto s, hypo, low t HEDS ETC. thanks in advance!

Should have specified this is 25mg bi weekly intramuscular it’s written as .25ml and formulate 100mg/ml done once bi weekly intramuscular

I’m on all 3, estrogen, cycling progesterone, and testosterone injections. The estrogen I have is a topical cream( .5 1 click per day). So my T went way up to 150 which I know a lot of people like….it has helped in a few ways, but my estrogen barely went up in 3 months on it. I’m currently on 15mg of T per week. My SBHG is high (122) and my cortisol is low (7 in am). Has anyone noticed testosterone messing with estrogen or is that probably a separate issue?

Hi, I have been on T injx almost 3 months. The first 4 weeks were so hard because I went from T cream to injx and I had to wait for the T cypionate to build up to reach steady state. But around week 5 I started to feel so much better, and I felt good for a few weeks. For the past few weeks though I've felt really awful again. Increase in body pain and anxiety that I haven't felt in a really long time, with what feels like a fast heartbeat, feeling hot and sweaty and nervous stomach and frequent urination, it just feels like my body is stuck in fight or flight which also messes with my state of mind so my ability to enjoy anything is shot. Im also tired but wired because even though I'm anxious I feel exhausted much of the time. The progesterone I take at bedtime at least calms me down enough to get good sleep.

My T levels were not crazy high when tested a few weeks ago, but I'm wondering if it went too high for me personally. I am pretty sensitive to hormonal fluctuations in general and felt horrible when my progesterone was too low and E was high.

4/15/26 lab results in my "trough":

Total T - 94

Free T (calculated with SHBG) - 1.13 ng/DL or 11.3 pg/ml

Estradiol- 120

For reference, I was coming from total T of 29 on the cream, free T 3pg/ml in late January. I was feeling pretty balanced then but could use some more energy, and was sick of applying the cream twice a day on my labia.

Has anyone else felt like anxiety and tension and other mental health issues came into play when they went past their sweet spot? I'm so tired of trying to balance this all out.

I am 40F and was experiencing nigh sweats, hot flashes, anxiety, mood swings and a non existent libido. I started injecting testosterone about 5/6 weeks ago and my testosterone level just came back at 9.1 (from 3.1 in Feb). Should I be worried? Is this too high?

Starting a compounded cream at 6 mg per day to be rubbed on inner thigh or inner arms (uno dose)

What are your experiences on testosterone
Does 42 mg a week sound high to anyone else??

Once I start this is that just my life? Like I’ll be on it forever and need to closely follow labs?

My doctor won’t answer my questions unless I schedule an appointment and everything is out of pocket. $250 for a 15 minute virtual phone session.

I would have asked these questions at my appointment, but it wasn’t prescribed until after my labs came back. And now he’s refusing to answer my questions unless I book an appointment. Red flag.?

Hello all!

I’m a 53 year old female counting months to see if I’m truly in menopause. I blew straight through peri, I believe, without realizing it because I was taking an oral birth control pill (which I have now discontinued). I have adrenal insufficiency and my adrenals don’t produce DHEA, therefore, my T is nonexistent.

I have been chasing after a resolution through T supplementation for a year and a half now. I started with cream, gradually increasing dose up to 10mg per day. Then, I went to sublingual troches, the equivalent of 10mg a day. Neither resolved lack of libido, muscle weakness, etc.

I changed providers to one who would prescribe injections, and she started me on test cyp 5mg, twice a week. No improvement in symptoms. We fiddled around with estrogen patches and progesterone pills, changing dose, etc, but still didn’t find resolution. My provider gave me free rein to experiment with upping my test cyp injection and just told me what signs to watch for in terms of over replacement. My blood levels looked much better on the injections vs cream or troches, but I still only had a T of 60 when she said I could go as high as 180 (ultimately, she cares less about numbers and more about results).

At first, I experimented with 6mg twice a week. Still no change. Then, I went to 7mg twice a week. Started to feel a little better, but still not there. Last week, I went to 8mg twice a week and BOOM, results. I was like a sex kitten last week with my libido and my muscles felt better and hot flashes better. But, I’m concerned to be injecting that high as it seems the average woman is good on 10mg per week. I also have one additional question.

Is 16mg a week just way too much for a woman? I have no acne, excess hair, etc. I’m just feeling better.

A second issue I’m having is that it takes about 12 hours to kick in after injection, I spend 2 days feeling great, then a day feeling like total crap again before I inject. Is it reasonable to take that 16mg and divide by 3 and inject 3 times a week instead of two,to keep the levels more stable in my bloodstream?

Thank you for any and all feedback! 🤗

Long story short: first few months on t gel I felt like I was back to my old self with libido. Amazing results. Then it totally fizzled. I can't understand why. Dose increase helped temporarily and then fizzle again. No room to increase now according to dr although oddly my T is lower now than before I started (!?). But still normal range. Dr has said it might not be doing anything anymore/maybe I should quit. Interestingly he never says that about estrogen nor progesterone... Both E and P were added a few months after the T. He doesn't measure levels of p and e. My problem now is: how can I possibly tell what is doing anything? Looking to hear from others as to how you decided to pack it in? Switching to inj isn't an option.

What days and times do you take your Injections?

Any one else get labs drawn and T level at 363?
I knew it felt like it was high cause libido was in overdrive.
But only side effects I have is slight facial hair.
I was on .20 ml injections once a week of 200ml T
Doc dropped me down to .1 ml injections now.
She said basically I’m a super responder.
I’m also on estrogen and progesterone.

I was on 5mg of T cream and was balding after 6 months. Started oral minoxidil and Finasteride and cut my dosing to 3mg a day. I lost any desire or interest in sex and I also don’t get any pleasure. However, this is the most emotionally stable I’ve been in years. I just started 4mg injections of cypionate and was curious to hear from others who switched from cream to injections. I would love to hear if this was a positive change for you or a negative one and why.

Has anybody ever had elevated prolactin levels during TRT therapy? My hormone clinic provider wants me to follow up with my PCM and my PCM thinks it's from the testosterone but hormone provider does not. From the little research I did, it can happen through aromatization in which its converted into estrogen and that excess estrogen stimulates prolactin production. My estrogen levels were at 70 though.

Debating adding 3mg boron to improve free T without adding more T. Currently on 1.5mg eod t prop, and estrogen has shot up a lot, and I don’t want to add any more T as it will just convert to E. Wondering if I need to cycle it on/off every few weeks? Has it worked for you long term?

Hi Ladies! I've been feeling great on daily 1mg T Prop injections for the past 3 weeks. Before starting T, I optimized E & P (post menopausal). I added T because, even though E & P were a huge benefit to my life, I still felt so sluggish at 3pm every day and it was hard to keep a steady work-out routine. My total T was about 20 and my free T ranged from 0.8-1.8 before T.

I went ahead and got preliminary labs done at the 2 week point and everything came back looking pretty reasonable. Most importantly, my Total T at trough (24 hours post injection) was 86ng/dL and free T(direct) was 1.2pg/mL. SHBG was 72 nmol/L (same over the past year and a half). My hematocrit went from 46 to 49 - but I do live at high altitude (9,000+ ft). I should keep an eye on that. The weirdest thing I saw was that my estradiol level came back higher than I've ever seen the past year and a half at 249pg/mL. This is weird because I am only using 0.0875mg estradiol patches changed twice weekly (I use a 0.05 + 0.0375 patch together). In the past, the highest I had seen my estradiol was 123 and lowest about 60 or 70. ChatGPT (I know, its AI, but I asked) said that maybe the assay that was used counted some of the T into the estradiol reading. I used Lab Corp test 004515 for Estradiol and Lab Corp test 140103 for Total and Free T. My FSH was 4.8 so that is more typical for 'reasonable' estradiol numbers. I did change my patch about 12 hours before the test, but I find it hard to believe that the patch "dumped" and "peaked" so high. I have zero high E symptoms (breasts aren't tender, in fact a bit deflated, no bloating, no spotting, etc...). Only thing I did differently was add in the T. I know, I know, I'm supposed to test before a patch change, but a snow storm came in and I changed test date because I was mostly interested in getting preliminary T results.

For T prop, I'm assuming that my trough numbers (TT 86 and FT 1.2) are lower than what my body is seeing during peak levels during the day time. I feel a ton more energy, libido has increased to a great level (I have noticed some clit growth in a great way), I'm sleeping great... overall I feel good so I'm going to stick with 1mg per day. Any thoughts?

Hi! 31F, started out at total T of 5 and on t prop - Idk if this is a dumb question, but considering the shorter half life of T prop, can you increase quicker or is still best to go slow? I have been slowly creeping up (started at 2mg EOD for 6 weeks then upped to 3mg as I didn’t feel much) and I feel better as in not exhausted and slightly regaining clitoral sensation after having absolutely none for a few years but still lacking libido and tired, moody. I just had labs done and my total t is 93, e 30, shbg 34. No side effects besides some more oily skin but I was dryyyyy to start. Wondering if going up to 4mg EOD is too much too fast since I started in February. My provider prescribed 14mg twice weekly but I decided to do EOD and start slow. Should I wait it out at this dose or would I know by now since I’ve been doing 3mg EOD for about a month? Thanks all :)

I have been on testosterone injections for year 1/2 and I’ve run into a side effect that’s really stressing me out. Almost overnight, I’ve developed a lot of coarse, black hairs on my chin. I do 10mg of 50mg testosterone cyp. Compound
It happened so fast that I think I should skip my injection or stop for a few week because I’m worried it’s just going to get worse. I’m feeling pretty frustrated because I didn’t expect it to give me issues to manage.
Has anyone else experienced this "overnight" hair growth?

• Did stopping or lowering your dose help, or did you have to add something else (like Spironolactone) to counteract it?
• How long did it take for the growth to slow down once you made a change?
• Are there any specific topical treatments you’d recommend that won’t irritate sensitive skin?

I’m planning to talk to my doctor, but I’d love to hear some "real world" experiences before I go in. Thanks in advance!

Does anyone do cream just a couple times a week? I'm having mega mood swings even in the lowest dose (.25 mg).

I am SUPER sensitive. I'm not sure if I should just stop or cut back. It's been a week. My nurse requires an appt for questions 🙄