During the reign of the Empire, did Vader (or Palpatine) ever fight any Force sensitive threats that were wholly unrelated to the Jedi or the Sith?
It was a thought that came to me. I know the Order 66 surviving Jedi would be the most prominent Force users but I feel like it would be plausible for him to come across unrelated Force sensitives by chance. Perhaps the Empire is invading a planet and there is a local group of Force sensitives as part of the defending army.
I know during the Clone Wars, Palpatine stepped in to deal with Mother Talzin but was curious if there was anyone during the time of the Empire that he considered a threat that had no connections to him or the Jedi whatsoever.
Regarding the Sith, I was not counting Inquisitors that turned treasonous like Reva or other Dark Side minions of Palpatine that were used to test Vader like some Legends stories had. Lord Momin is a bit of a gray area since he was a Sith but has no ties to the Banite Sith.