r/TTCEndo

I am a 29F. Most of my adult life I believed I had endometriosis. I had every symptom for it in the book. Within the last 2+ years when my husband and I started trying to have a baby and never conceived I knew somewhere deep down Endo was the issue.

We sought out fertility care last March after a year of trying unsuccessfully and we proceeded with IVF rather than wasting time on IUI. I knew I ovulated regularly and my husbands semen analysis came back great, so we were hopeful IVF would do the trick quickly. Never once was I tested for inflammation markers even though I told them I was suspecting endo was present.

I had a very successful egg retrieval in June last year, and in October of 2025 we transferred our first Euploid embryo. It failed to implant. In December 2025 we transferred a second Euploid embryo, it also failed to implant.

At this point I knew I had to stop, heal my heart and try to find out if Endo was truly the issue. In January of this year I sought the help of a renowned endo specialist who without question recommended excision surgery for me.

In March I had a successful excision surgery where he found and removed stage 4 DIE. It was everywhere. I stood no chance of getting pregnant previously with the severity of my endo. They also found that I had Endometritis from my biopsy performed during lap which I took one round of antibiotics for.

April 15 began my first full cycle TTC after the surgery. 3 days ago, May 7th, I had my first EVER positive home pregnancy test. May 8th, I read the words "pregnant" on a digital test for the first time in my life. I fell to the floor and Thanked God.

Obviously it is still very early, but I would not even be this far had I not trusted my gut and gotten the help of an endo specialist who knew how to treat me.

Find the specialist. Get the surgery. Change your life. I'm wishing everyone here the absolute strongest baby dust. It is possible for us to conceive. Please don't lose hope. Sending to much love to each and every one of you. My heart is with you.

Please pray I have a sticky baby in my belly. 🙏💕

Has anyone had something similar after an excision laparoscopy? My clinic want me to do a fully medicated FET however it’s not something I really want to do. They also don’t personalise to endo patients either 🙄 from looking all over this group and Reddit etc. I’ve come across a protocol which I think looks really good and I feel more comfortable with. Has anyone else had something similar?

- Day of surgery have my first Lupron injection.
- Suppress for 4-6 weeks.
- Week 4-6 a natural bleed occurs or induce with norethisterone. Give it some time.
- When the bleed occurs have the baseline scan and bloods to check ovaries are responsive again.
- CD3-7 start Letrozole.
- CD8-12 monitor with scans.
- When the follicle is ready do a trigger.
- Start vaginal progesterone and lubion injections.
- 3-5 days before transfer start prednisone. Also start Claritin and Pepcid.
- Clexane start on trigger day or transfer day.
- Then transfer.

Hi everyone! I have been a constant lurker here and on many other such communities here on reddit occasionally asking my share of advices and affirmations for my prior uncertainties.

I was diagnosed with endometriosis when I was 19 and still in college. Despite having been gas lighted by mother that it's just period pain and i "apparently had low pain tolerance and women are able to bear even more"; I was hospitalized on one of the occasions of my very severe painful episode. The doctor said I had huge 9-10 cm chocolate cysts on both my ovaries, multiple fibroids in my uterus and the anatomy of my system was all disturbed. The doctor then recommended I do surgery only when the symptoms are unbearable and when I need to bear children. I was put on birth control and on which I remained for next 8 years. I did have irregular bleeds here and there but I was able to live my life by taking a withdrawal period bleed every 3 months. I was able to do well in career and enjoy my life. I met my now husband at 26 years of age and I told him about my condition after two months of dating and I told him he was free to leave me if he wanted to since conception would be difficult. He however to my surprise accepted me and I melted right away.

In 2024 we consulted many doctors while we began our journey to conceive. Many recommended that since my environment was not conductive, I undergo a laproscopic surgery which I did in December 2024. The doctor said it was a possibility that they would have to remove one of my tubes because it was all filled with blood. But by God's grace, everything went well and my anatomy was restored and endo was removed along with fibroids. It was a painful recovery. My work suffered but I bounced back through the help of my parents and spouse.

However I wasn't prepared for the journey to come. My Ahm had sharply declined due to endometriosis, constant use of pills and the surgery. Before surgery it was barely 0.65 and afterwards it came to be 0.45. The doctor said my endo could come back and I had to act swiftly after the three months healing period. We tried naturally for two months and failed. We did IUI with trigger shot and failed. We moved to IVF with so much hesitation since I was only 28 and we couldn't believe what we were going through. We kept our journey after the surgery very private. Nobody knew how I was suffering silently in 2025. The entire year of physical pain, mental suffering and deep longing.

Our self egg retrieval failed as we only yielded one embryo of poor grade. The doc said I had really poor quality eggs because endo destroyed the quality of it all. We moved on to donor eggs with heavy heart. First FET failed. I had taken break from work because my manager was shit and I couldn't continue. It was so so hard. I was literally harassed at work. I couldn't bear what I was going through. It was so so lonely. We went for another FET via the same donor egg embryos which had been earlier stored. It failed again. I was devastated. I was so broken. I wanted to take a break from life and go somewhere. I went to an Ayurvedic retreat centre for 3 days all alone. It was so refreshing. I cried during mediation and tried to relieve a lot of stored trauma and emotional wounds in my womb. I moved onto my third donor egg FET from another donor. By this time it had costed us a lot of money but my husband was so so kind to me and so supportive. I was trying to manifest a good life. A happy life full of kids.

I couldn't think of what was to occur in the same month. I lost my father to a cardiac arrest suddenly. It was so painful. I had to drop off my treatment to go home. I stayed there for a month. We had told my parents about IVF a couple of months before and my father had been very supportive by saying that we were welcome to come stay at my parental house if we wanted to take treatment from that city. He said he'd always support us no matter what and that I have to be brave for everything. It felt like my entire world had shattered. I was on a break from work, my career suffered, I had lost the person I cherished most since my childhood, I had to take care of my mother, I had to stop my treatment.

The following cycle I decided I needed to just let it go. I was so tired all the time running errands for my mum and taking care of many many important tasks at home after my father's death. I had taken letrozol during that cycle upon the recommendation of my doc because we didn't want to waste any cycle. I had ordered COQ 10 supplements and pressed lube which my husband earlier thought wasn't necessary. I had intercourse barely three times while I timed them roughly. Mind you I wasn't in an okay mental state. Physically I was tired and exhausted. I was supporting my mother who was grieving and my brother who was also going through a divorce. It was so difficult.

I had surrendered to God. I couldn't take it anymore. I would pray and cry everyday. Lo and behold, I fell pregnant the next month. I had missed my period. I had minor spotting and major cramps. I couldn't believe the tests because sometimes there are false positives. We were outside having dinner with some relatives from my in laws place when the beta HCG results came to be positive. I couldn't beloved it. The doctor had said it's impossible for me to conceive naturally given my endo and later diagnosed adeno.

I'm presently 9 weeks 5 days pregnant. Although still early but the baby is doing fine. I just wanted to share my story in case anyone out there is in the same state as I was in. I was sad, lonely and full of despair. May be God saved me or may be it was my father who blessed me before leaving. I don't know. All I know is that Doctors are not God, they can't do what God can. I'm so thankful and grateful for this. I hope my journey inspires someone other there looking for hope.

I found out I’m pregnant yesterday so I’m probably about 4 weeks along. I have endo and adenomyosis. I’ve been taking Ritual prenatal for a month or so but now I’ve been reading it’s missing important nutrients.
What are some recommendations for prenatal (especially knowing I have endo). Not too concerned about price. TIA :)

Hi, Looking for some advice. To keep it short - my Receptiva test came back at 3.4.

My Dr is saying we could try another transfer (and do a month on birth control as a lighter treatment then Lupron), but I am now concerned he is underconcerned for the Receptiva score. I've heard now through my doctor and read via some studies, that there is some skeptisism about how seriously the receptiva results need to be interpreted, so I 'm just feeling really confused what plan to follow and if the Receptiva advice should be taken very seriously. Did anyoen get back a higher number and not follow the advice and get pregnant? Or get a second opinion and different doctors had different advice whether to treat it with Lupron or just try a month of birth control so suppress a bit? Thanks for all adnice.

My husband (33M) and I (29F) have been trying to conceive for over 18 months. We got sperm analysis after 6 months of trying and found out numbers were low. Made lifestyle changes and numbers got better but still not conceiving. I’ve had regular periods and bloodwork has been all normal. I did have a Right sided endometrioma so I was always worried about that. We met with our REI at around the 1 year mark and my SIS in February was normal besides some small fibroids. Ended up doing 1 cycle of letrozole and then moved to IUI. Pre and post wash sperm numbers weren’t good which was devastating. The first IUI failed. We started discussing possible IVF down the line. We proceeded with second medicated IUI which failed as of two days ago. I heard of IVF failing cus of endo so decided to get a second opinion from an endo specialist. The US today showed possible right adhesions and right tube dilated most likely hydrosalphinx. I had noted something in my screening US but no one mentioned it. The Doctor recommended retrieval then surgery and possible tube removal. This all came out of nowhere especially with normal SIS a few months ago. My mind has been racing and i cant help but feel that letrozole caused worsening of existing endometriosis. I don’t know how to proceed and feel like my world is collapsing. I’ve always loved kids and my biggest fear in life was infertility. Sorry is this sounds like I’m rambling just looking for words of support and advice.

I should be grateful that she's telling me a potential pregnancy will not be negatively impacted by endo but that's not what I'm seeing online from people's experiences?? Obviously her saying this could be good news but I'm trying to be informed on whether or not to get a lap before I try conceiving again.

I've technically been TTC for 3 years and only just learned about the endo last week (just from clinical diagnosis, no lap) and then today that I've likely not been ovulating effectively or at all despite regular periods. (Possible endo-caused) So instead of going straight to ovulation meds, I asked her if I should first take care of any endo lesions to reduce complications and she said there are no complications caused by endo??

The only complication she said was early miscarriage but if you make it past the first trimester, she claims it is like any other pregnancy and while other factors can cause other complications, endo isn't a contributing factor. Thinking of getting a second official opinion because she's sorta confusing me.

Has that been your experience or should I be more cautionary?? I want to be informed but please don't scare me with any horror stories either...thanks 😅🙈

Also have PCOS and autoimmune disease

I had excision surgery for Stage 3 endometriosis about 4 months ago. Since surgery, we’ve actively tried every single cycle. I ovulate regularly, my cycles are completely normal and predictable, I take all the vitamins, eat anti-inflammatory, track everything, etc. On paper everything looks “good.”

Last night I ended up in the ER on CD22 because of a ruptured ovarian cyst. The reason I went in is because I’ve actually had to have surgery in the past from a cyst/bleeding situation that would not stop, so I get really nervous when this happens. Thankfully this time it didn’t require surgery, but emotionally it just broke me a little.

I asked my doctor what else we should be doing (meds??) and basically got told “just keep trying.”

I feel stuck in this weird gray area where the only thing ever found was endometriosis. Which also makes me wonder: if I originally fell into the “unexplained infertility” category but then they found Stage 3 endo during surgery, are we still considered unexplained infertility? Or do doctors basically assume the endo was the cause and now consider you “fertile” post excision?

Which brings me to my other questions:

•	After excision, are we still technically considered to “have endometriosis” forever? I feel strange saying I have endo when I know I’ve had it removed?

•	How long did it take for symptoms or lesions to come back after surgery for those who had recurrence?

•	Did anyone still struggle to conceive even after a successful excision?

•	At what point did your doctor recommend meds, IUI, IVF, etc. instead of “just keep trying”?

I think what’s hardest is feeling like I’m doing everything right and my body still just… isn’t cooperating. Every month my period shows up exactly on time and it feels crushing.

Would really appreciate hearing honest experiences, especially from people who conceived after excision because right now I’m feeling pretty hopeless.

Hi girls, I recently saw my first ever faint positive line, but it ended up being a chemical pregnancy around 5 weeks. Has this happened to any of you? Do you know what some possible reasons could be?

My doctor didn’t really elaborate much and just told me to keep trying naturally this month and come back next month. I’d really appreciate hearing your experiences or insights because I’m feeling a bit confused and anxious about it all.

Hey dears,

I was into unexplained infertility issue.
Later they suspected I have symptomless endo and it was right. I had stage 2 endo they removed it and most of them was back of the uterus. I think because of that I may had a very constipation.

Today is my 3rd day of my lap and my period already started. I spoke with my doc about the next step. She’s like asking my suggestion. What may be the right next step? Should I go next transfer but when?
Should I take lupron for 2 to 3 months and then transfer?

Please share your experiences.
I read many stories that after lap there is a failed transfer but after 3 months of lupron there is a positive.

I'm a 37yo first-time IVF-er with Stage 3 endometriosis and DOR. My AFC was 5, AMH 0.65, and went on the max 450iu menopur for ER, resulting in 2 mature eggs, both of which were fertilised and frozen on Day 3.

We transferred our 8-cell earlier this month, and shortly after, I had the worst stomach flu ever on cruise. The cruise doctor was mad at me for risking the transfer, I had high fever, shivering under three thick blankets and with two hot water bottles by my side. I thought it was a lost cause and when I got back to the IVF clinic, we discussed the transfer of our last 6-cell embryo before our beta.

Lo and behold, our little trooper made it. I'm 6 weeks 3 days and we had our first scan today. Heart beat 121, measuring 0.49cm.

The entire process has been incredibly difficult. We were always advised not to have our hopes up and our cautious doctor finally told us to let ourselves feel the happiness for a bit because our numbers are good. The nurses at the IVF clinic were super happy for us as well to graduate the clinic.

We look forward to welcoming the little bean earth side on Christmas Day (or earlier!)

To Singaporeans who are researching on IVF, I did it with SGH Care Clinic and I highly recommend it because the nurses are simply the best and most supportive.

Happy to answer any questions. I hope my sharing gives you all IVF warriors a little bit of hope and positivity!

Hi, how many cycles did it take for success with stage 3-4 Endo without excision? My FS has recommended we go straight to IVF due to risks associated with surgery.

Feeling discouraged and would appreciate your experience if you have been through a similar situation.

I'm 34, just done 2 rounds of IVF and have one frozen embryo to show for it.

I've always thought I need surgery to get pregnant. My endo is deep infiltrating and stage 4.

My IVF clinic say because I have low amh that I need to do IVF because surgery will lower it more.

I'm lost. How many more rounds to get how many more embryos. And that's before we even try to transfer. I've had 4 natural conceptions that resulted in miscarriages and I just feel the same thing will happen again.

Has anyone my age had the surgery and gone on to naturally conceive?

Had 1 ectopic, and 4 chemical pregnancies over 2 years. Laparoscopy in Jan this year confirmed and excised silent endo on my bowel. Since then I’ve had 3 back-to-back chemical pregnancies.

Trying to understand what difference IVF would make if I can get pregnant easily, but they don’t stick?

I’m 34 f and my first lap is scheduled June 5th

I’m doing this for infertility/diagnostic

8 years TTC
I think I have silent endo, I don’t have many presenting symptoms. I have had a long journey trying to get diagnosed and I’m finally here, ready for answers.

What I do know:

I have bilateral endometriomas, ones 3.5 the others around 1.5 - they are small. Can see on imaging

My AMH came back as 2.15 a few weeks ago.

HSG 2ish years ago- tubes open

I was going to an infertility clinic who was forceful about IVF, they straight up ignored my endometriosis and drilled into my head that if I did anything about it, I’d harm my chances.

It never felt right not understanding the root cause- the line of work I’m in focuses on root cause and I just mentally can’t ignore the feelings I have when I think about IVF without a proper diagnosis

So many women go to IVF and are subject to horrific treatment.

Anyway- I’m just looking for some positive experiences with lap surgery, and TTC.

My OBGYN convinced me (25f) to do an exploratory lap. I had some cysts on ovaries. We also knew I had a pretty severe bicornuate uterus. Lap revealed extensive stage 4 endo. It was covering my bowels, bladder, ovaries and uterus. My left fallopian tube was removed. She said my right fallopian tube was “hanging out by itself” and unaffected. My ovaries were shifted due to the severity of the adhesions.

My OBGYN called me and told me she recommends IVF and that it is unlikely if not impossible for my husband and I to get pregnant without IVF. She reported she did “the best she could.” She said she doesn’t see how it is physically possible with how severe my anatomy is altered that I could get pregnant. It was tough news hearing this, bc I was hopeful given my unaffected tube and her taking care of the majority of the adhesions it would be more likely for us to conceive.

I’ve reached out to a few IVF clinics in DFW. But before we throw money down the drain on that, I want to check in with an endo specialist in DFW to make sure my body is ready for pregnancy. Any recommendations? Also any stories of hope of people being told they could never have a baby and ended up able to are so encouraging for me to read right now.

Hallo zusammen, ich habe eine einjährige Tochter und bald eine Bauchspiegelung. Welche Erfahrungen habt ihr mit der Genesung gemacht? Es ist meine erste und man hat auf dem MRT einen kleinen Herd in der Gebärmutter gesehen, ansonsten nix. Ich vermute aber, dass es an mehreren Stellen sitzt aufgrund meiner Beschwerden. Ich zweifel, ob ich die Bauchspiegelung aufschieben soll, damit ich mich um meine Tochter kümmern kann oder ob ich sie jetzt machen soll. Hilfe habe ich wenig, mein Mann wäre nur nach der Arbeit da, tagsüber muss ich Hilfe organisieren. Ich weiß, dass man nicht schwer heben darf, gerade das ist mit meiner Tochter ja kaum realisierbar. Wie schätzt ihr das ein?

Anyone using peptides to help while TTC with endo?

I started my period April 30, which was the same day. I had my stage one Endo removed. I also had a hysteroscopy and my tubes flushed. It’s as if my period completely disappeared and I only had minimal spotting for three days after the surgery. I began having fertile cervical mucus a few days ago, and I just took an LH test for the first time and I either rising towards my peak or just coming off of my peak. I’m super frustrated to miss another month of trying, especially since my husband will not be around for the next couple of months.

My doctor said we can resume sex two weeks after the surgery, but I’m tempted to keep LH testing and if I see my peak in a couple days, TTC before the 2 weeks is up. Is that the worst idea? We would be cleared to have sex in 6 days from now.