Anyone else experience this with Effexor dose increases?
I started Effexor XR at 75mg, then went up to 112.5mg and 150mg, but I still got no real benefit for my severe depression. Today my psychiatrist increased it to 225mg and told me to stay on it for 10 days, and if there’s still no improvement, I may need to go up to 300mg.
What’s frustrating is that after every dose increase, I feel better for a few days once the second week starts — almost like it’s finally working — but then I crash again and the depression comes back just as hard.
Has anyone else experienced this pattern with Effexor? Did higher doses eventually help, or was this a sign the medication just wasn’t the right fit?