u/Entire_Giraffe_228

I haven't started minoxidil yet. It would have to be oral as I have too many sensitive small animals as pets that topical is just not worth risking. Its just not something that's realistic for me.

But the problem is I already have PCOS. I don't have actual hirsutism, but I do have some body hair which I CANNOT grow more of (It will trigger my painful skin condition, Hidradenitis) I really do not want to end up growing facial/body hair, Im really thankful that I don't have hirsutism somehow despite having PCOS, but I'm very scared minoxidil will trigger it because of the risk

Will being on Spiro 100mg and Yaz BC pill help to prevent face/body hair growth?

Ok so it makes sense that Accutane raises cholesterol but I'm worried about topicals, everyone seems to say that it's impossible for just a cream to cause higher cholesterol, which makes sense, but this study says that it can-

https://www.researchgate.net/publication/375207998_Adapalene_Gel_Therapy_in_Patients_with_Moderate_to_Severe_Acne_Vulgaris

This is just for Adapalene gel, it says "continuous Adapalene therapy caused an increase in cholesterol, triglycerides, LDL, and HDL above the normal range with a grade 1 increase."

Would it make sense for this to be the same with Tretinoin cream?

I've been wanting to start Tretinoin but I already have cholesterol issues so now I'm worried, should I be?

I hate this diseases, it destroys everything, not just the flares, the inflammation is in the entire body, increases cancer risk, heart attack risk, apparently it even ruins the collagen in your skin, so now I feel like I'm going to get wrinkles and premature aging (I don't care if it's vain to be worried about that.) Its just a horrible disgusting evil painful disease. I hate that my body is attacking itself from the inside out. I just want to cry. There isn't a single person in my life who understands. They just tell me I'm not cleaning myself enough - I literally take two or three showers a day and Im unhealthily obsessed with cleanlieness. To the point I feel dirty if I produce a single drop of sweat. I've had to avoid going out with friends because of my flares in my groin and I just make up a lie for why I can't go because I am NOT telling them I have this. It's too disgusting. I hate this

Ok so it makes sense that Accutane raises cholesterol but I'm worried about topicals, everyone seems to say that it's impossible for just a cream to cause high cholesterol, which makes sense, but this study says that it can-

https://www.researchgate.net/publication/375207998_Adapalene_Gel_Therapy_in_Patients_with_Moderate_to_Severe_Acne_Vulgaris

This is just for Adapalene gel, it says "continuous Adapalene therapy caused an increase in cholesterol, triglycerides, LDL, and HDL above the normal range with a grade 1 increase."

Would it make sense for this to be the same with Tretinoin cream?

I've been wanting to start Tretinoin but I already have cholesterol issues so now I'm worried

Apparently biologics can raise cholesterol. Has this happened for anyone taking them?

Biologics are basically my last treatment I can try and my last hope, but I already have high cholesterol. Apparently HS is associated with bad cholesterol anyway so maybe that's expected. I'm scared I won't be allowed to try a biologic because my cholesterol is already bad. Any experiences??

I see that some people get parts of their skin removed for HS, and maybe this is a dumb question but what exactly does it do? Does it stop HS from reappearing over the scar area left from the surgery? Like if you have HS all over your groin and get the surgery to remove the skin, what happens? Doesn't the HS just come back or move somewhere else? If it helps do you think the surgery is worth it? It looks really intense. I'm worried this is in my future one day my flare area is my groin and I'm so upset

My insurance doesn't cover a GLP-1 until you get diabetes, so Im not sure if I will be able to get one soon, but I know I'm going to have to one day. I have insulin resistance and have really been struggling with it. On the main pcos sub I do see people discuss glp-1s but there are some users who seem to be against it and push for diet only (mainly keto/low carb high fat diet). I have to watch my cholesterol so keto isnt an option for me, and definitely not a high fat diet, which is just gross to me. If you take a GLP-1 for PCOS and insulin resistance do you still have to go keto or low carb or whatever??

Also, Ive read that GLP-1s can result in hairloss. Has it done this for you? Seeing as hair loss/thinning is one of my pcos symptoms, I'm worried about it

I've been on spiro for pcos for a bit more than a year, basically I HAVE to be on it because of this. It completely wiped out my acne which is great but I feel like my face looks thinner, dryer, less plump than ever? And Im overweight, my face was fat before but it looks thinner now - but not in a good way. Its mainly much thinner under my eyes which is really aging me. There's lines and malar bags when they weren't there before and its extremely hollow and purple. Seeing as spiro gets rid of water weight, could it be this?? My face looks better when its puffy in the morning. Does getting better moisturizer help combat this ? Or maybe starting tretinoin? Yeah I know it could be simply aging, but it has dried out my skin