u/Cal-Augustus

There are known medical differences between cis men and women, e.g., longevity, heart disease, stroke, diabetes, depression, etc. Are there any studies on how HRT affects a trans individual's chances of developing an ailment they otherwise wouldn't if not for HRT?

For example, nearly 80% of the estimated 10 million Americans who have osteo­porosis are female. Can a MTF trans individual with no pre-HRT-identified osteoporosis expect, after starting HRT, to see any greater propensity toward developing it if there's a history among her female relatives?

Why is this happening? If this is normal operations, I want my money back.