it's always very interesting to see animals' reactions to human invention and see them make sense of a world far beyond their understanding.
You can now clone your dog, but should you? 🐶
Bioethicist Insoo Hyun explores how dog cloning works and why a genetic copy is not the same as bringing a beloved pet back. Dog cloning involves taking DNA from one animal and placing it into an egg cell, where that genetic material must be reprogrammed to direct development from the beginning. That process is complex and imperfect, which can raise the risk of developmental problems and other health issues. If the original dog’s cells already contain mutations, those can also be passed on to the cloned puppy. And even with nearly identical DNA, environment, development, and life experience all help shape how a dog looks, behaves, and interacts with the world.
You can now clone your dog, but should you? 🐶
Bioethicist Insoo Hyun explores how dog cloning works and why a genetic copy is not the same as bringing a beloved pet back. Dog cloning involves taking DNA from one animal and placing it into an egg cell, where that genetic material must be reprogrammed to direct development from the beginning. That process is complex and imperfect, which can raise the risk of developmental problems and other health issues. If the original dog’s cells already contain mutations, those can also be passed on to the cloned puppy. And even with nearly identical DNA, environment, development, and life experience all help shape how a dog looks, behaves, and interacts with the world.
I am going to do a growth kinetics of multiple flu viruses with 4 harvesting timepoints on 2 cell lines. I calculated that one trial takes 70 * 6-well plates, which is a nightmare since I am new to virology.
Any tips and tricks to perform plaque assays efficiently? Thanks in advance.
Well technically my entire class is failing and half already dropped it honestly dropping it would be the smartest thing to do for my GPA but honestly i don't care anymore i paid for the class out of pocket im going to see it through to the end and retake it in the fall and pass. Take this post as a way to show my commitment or a way of acceptance i need to accept the fact that im not passing. Its been stressing me out at night and just telling myself that im a failure over and over and over.
but i want to look back and understand where i messed up so i don't make the same mistakes
I didn't know how to study for the first few weeks. Especially for biology, im not going to blame my high school for not preparing me this is completely on me.
I was to distract. I had originally deleted all my social media and everything was going great i haven't touched tiktok in a very good while but my Lab partners said that they prefer insta over cell number which is understandable but daym i kind of did get a little to into social media again but i deleted it again
Terrible time management. I love how i always tell my self that i wont do stuff last minute but here i am doing a research paper the day its due. I definitely need to improve on this
Theres are definitely other stuff i can work on but in these last 5 weeks all i can do is my best and come back smarter and better in the fall, I have all the PDFs for the chapters and textbook so i can definitely go over it again in the fall. wish me luck guys and gals (sorry for all the spelling mistakes im clocking in for work soon)
Hi everyone,
It's my first time posting here.
Recently, I've been self-studying developmental biology. This is a new field for me (I have a bachelor's in biotechnology engineering, so most of what I learned was focused on industry), and I am fascinated.
To learn the basics I am reading the book \*Developmental Biology\* by Barresi and Gilbert, and I find myself especially interested in marine invertebrates.
From what I've learned so far, the main model organisms are sea urchins and tunicates, but I would love to dive deeper into this topic.
If you know of any articles, journals or books that could help me understand the current state and trends in developmental biology of marine invertebrates, I would really appreciate it if you share them with me.
Also, any advice is welcome :)
Hello!
This year I started a degree in biology and marine biotechnology, the degree itself is a lofe science degree with a focus on marine biotech.
I signed up to this program because its unique in the sence that only 2 institutes teach it with one having really bad reputation(I signed up for the better one)and I thought the unique skills I would gain could help me be a more apealing canidate for most fields if if I choose to switch.
I always loved zoology and marine life but, at the end of the last semester while studying for my cytology I realied I enjoy it more then the zoology courses
and this semester i really enjoy the chemistry courses(organic and phyisical).
should I choose to switch to another field in biology when choosing a masters will a unique skill set be nore valuble then a relevent one?
Scheffrahn et al. describe a drywood termite whose soldier caste has an unusually narrow, elongated head capsule with mandibles fully concealed by the frontal process. In lateral view the resemblance to Physeter macrocephalus is striking, including antenna socket placement mirroring eye position. Genetic analysis places it near Cryptotermes species from Colombia, Trinidad, and the Dominican Republic. Sixteenth known Cryptotermes in South America.
I hope it’s the right sub to publish this. Im not that bad maybe? I have some knowledge around because I took it for 5 years but I’ve always disliked it. I looked into some of the curriculums and it for sure involves chemistry but how hard is it? I have plenty of time to start working on it. And would appreciate any recommendations. Thanks!
I know obligate carnivores don’t get nutritional value from plants yada yada. I’m talking mostly about situations where carnivores make exceptions to help with certain deficiencies, like how sometimes cats will eat some grass to help with digestion. I looked all over the internet and can’t find a good answer.
Title: A Theory on Using CD36 as an Immune Targeting Portal in Cancer — Looking for Scientific Feedback
I'm not a researcher. I'm someone who lost my mother to breast cancer and is currently watching my uncle fight stage 4 melanoma. Out of that pain I've spent a lot of time reading, thinking, and developing a concept I can't stop coming back to. I'm posting here because I want honest scientific feedback — not validation. If this has holes, I want to know. If any part is worth exploring, I want it to reach someone who can actually test it.
The Core Idea
Most cancer treatment tries to kill cancer cells directly. My concept takes a different angle:
What if we could make cancer cells betray their own location — forcing them to become irresistible targets for the immune system?
The Mechanism
Many aggressive cancers — melanoma included — overexpress CD36, a receptor involved in fatty acid uptake. Tumors use CD36 to fuel their rapid growth by greedily absorbing lipids from their environment.
My proposal is to exploit that greed.
Engineer a lipid-based payload — potentially a modified lipid nanoparticle, similar in concept to mRNA vaccine delivery vehicles — that CD36-overexpressing cancer cells preferentially absorb. The payload would be designed to do one or both of the following once internalized:
Force antigen presentation — deliver an immunogenic peptide that gets processed and displayed on MHC-I molecules, essentially making the cancer cell wave a flag that killer T-cells can recognize and respond to.
Trigger immunogenic cell death — cause the cancer cell to die in a way that's immunologically "loud," releasing danger signals (DAMPs) that recruit dendritic cells and prime a broader T-cell response against the tumor.
The cancer cell's own metabolic greed becomes the mechanism of its unmasking.
Why CD36 Specifically
Overexpressed in aggressive cancers including melanoma, breast cancer, and oral squamous cell carcinoma
Already linked to metastasis and immune evasion
Healthy cells express CD36 at lower levels, potentially offering a therapeutic window
Using it as a delivery portal rather than simply blocking it preserves its role as a targeting mechanism rather than a blunt inhibition strategy
What a First Experiment Might Look Like
A relatively simple proof of concept could be run in cell culture:
Take CD36-overexpressing cancer cells
Expose them to an engineered lipid payload carrying an immunogenic peptide
Measure whether MHC-I antigen presentation increases
Co-culture with T-cells and measure cytotoxic response
No human trials. Just a starting signal.
What I'm Looking For
I'm not looking for credit. I just want to know if this is worth pursuing. If someone in a lab finds this interesting enough to explore, that's everything. If there's a fatal flaw in the mechanism I'm missing, I genuinely want to know that too.
Is any part of this scientifically viable?
Any replies are greatly appreciated
why every life have will of multiple?
virus which even dont considerd life have will to multiply.
I dont just why they consider them as a inferior when they are the one who makes knowleadge and doctor are the one who works on the principal they established for example a biologist discover something likely a drug for cancer doctor are the one who would go though trials on the patient that means they both are interdependent and by no sense they are inferior and at most of the times biologist is more up to date to any new researches
‚,Bone, adipose tissue, and the brain are tissues in humans where the primary effect of testosterone is via aromatization to E2‘‘
https://pmc.ncbi.nlm.nih.gov/articles/PMC8538516/
If i understand this correct, then estrogen is necessary for bone Development?
I'm doing a mock trial and I've done some research to find that pathogens within the betacoronavirus genus of zoonotic origin have outbreaks(SARS-CoV-1 2002-2004, MERS-CoV 2012-present, SARS-CoV-2 2019-2023), and while it's not part of the betacoronavirus genus, I've also found out that the black death has zoonotic origin. Within the betacoronavirus genus, specifically in the Embecovirus subgenus, the viruses known as OC43, and HKU1 are not considered zoonotic as they're thought to have been zoonotic but adapted to target humans and are no longer considered zoonotic and have not had outbreaks and only cause the common cold. Under the betacoronavirus genus, there are 2 viruses that have not been documented within humans and so they're not zoonotic either, and obviously have not had outbreaks. This basically covers what I've found out during my research for the mock trial, and if its true that zoonotic viruses and outbreak have a relationship, it would be a breakthrough for my mock trial. So do they?
I dont know this is the right sub but i wonder why we cant put axolotls regeneration on ourselves is it just because of the leevl of our Technology or we can put it but the side effects and ways to delete them is the issue like ik it would make us a lot easier to get cancer but then why we dont get more p52 like elephants and maybe idk we cant produce enough atp to fuel that kind of regeneration is it cuz just natural limits and adaptability or lvl of tech and knowledge isnt enough.