Is anyone here taking berberine and seeing changes in their HDL, LDL, triglycerides etc? I just started taking it and hoping to see lower LDL and triglycerides after a few months. Very hesitant to get on statins despite recommendations. Has anyone seen tangible results from taking it?
A 2026 meta-analysis of 10 randomized controlled trials evaluated the effects of NMN (250–1500 mg/day) on blood pressure.
Key Points:
• Diastolic blood pressure decreased by about 2.15 mmHg
• Systolic blood pressure showed a downward trend
• Adults 60+ saw ~3.9 mmHg reduction in SBP
• NMN was well tolerated across trials
Details:
Even small reductions in blood pressure can have positive effects at the population level. A ~2 mmHg drop in DBP has been associated with reduced cardiovascular and stroke risk. The data suggests NMN may provide modest support for vascular health, particularly in older adults where NAD+ levels decline.
A 2026 clinical study examined how NMN and NR (1,200 mg/day) affect NAD+ levels in both blood and brain.
Key Points:
• Blood NAD+ increased gradually and plateaued after ~2 weeks
• Brain NAD+ rose to about 40% above baseline after 4 weeks
• Effects were consistent in both healthy individuals and Parkinson’s patients
• NAD+ declined gradually over 2–3 weeks after stopping
This is one of the clearer human timelines for NAD+ kinetics. The data suggests NAD+ elevation is cumulative, not immediate, and requires consistent intake over weeks to fully manifest, especially in the brain.
Full Article: https://renuebyscience.com/blogs/scientific-evidence-library/nmn-nr-increase-nad-in-blood-and-brain
This is the second bottle in a row that has done this to me! I bought this bottle because I thought the last one was just a bad batch (as I wrote that, I realized that's still not good), but that was 6 months ago.
My throat now feels like it's on fire -- like when I had Covid, but x5.
I first started buying the sprays in 2024 and they hadn't done this back then.
What gives?
Renue by Science seriously needs to fix this. I'm legit questioning this having even been tested, because this really shouldn't be sold until it's fixed.
AND I know it's not just me -- there are other posts about this.
So I guess I'm really just wondering:
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When is everyone taking this?