CALR Type 1 +
Hi, I wrote here before, before I had many results.
I'm a woman, 38 year old.
I'm 2021-2022, my platelets were between 691 and 786. I wasn't sent to a hematologist because they thought it was reactive.
All results are from three dates in April:
Platelets (1451, 1305, 1177); Hemoglobin (144, 142, 129); Hematocrit (0.438, 0.423, 0.381); Ferritin (149, 186); LDH (437, 412). The rest of my CBC is all normal.
Few Ovalocytes and Rare Schistocytes.
I got this preliminary results from my bone marrow biopsy (it has been sent for an expert consult):"Right posterior superior iliac spine (bone marrow biopsy): Hypercellular, immature bone marrow with abundant megakaryocytes with dysplasia. Specimen consists of a hypercellular bone marrow as well as several blood clots. The bone marrow appears immature and there is abundant megakaryocytes of various forms including dysplastic megakaryocytes."
And I just got my gene mutation results back with CALR L367fs (Type 1) mutation at 50% VAF.
They also found a 5 cm lesion on my (non cirrhotic, healthy) liver, but my spleen is normal size.
This feels like pre-MF? Maybe progressing? What does the 50% VAF means in this case?
I'm spiralling a little bit, so thanks for all info you could give me before I get the final results and my follow up with my hematologist (I'm also waiting on the MRI for my liver).