Hello all,
My father (66) was diagnosed with PV approx 6 years ago, he was on hydroxyurea and started off having his blood taken out. He suffered a NSTEMI last July and had a double bypass which resulted in gastric ulcer complications and needed 4x blood transfusions.
Fast forward recently cardiologist noted murmur queasy leaky valve and heart failure. Hematologist noted recent blood test showed 3% myelocytes and 7% metamyelocytes in wbc. He was also severely anemic and had a blood transfusion last two days ago. His current symptoms are shortness of breath on exertion, intermittent chest pain, abdominal pain, lethargy, overall unwell feeling, slight pitting oedema in bilateral legs. Last night I noted he had a fever 38.1C and took him to the hospital. They admitted him and his hematologist came in and we’re doing another bone marrow biopsy as he suspects his PV has turned into MF and the leaky valve and heart failure etc may be secondary to the MF. He said he will try him on Jakalvi again even though dad said it made him feel a bit unwell but it might have been the heart issues not the medication. Otherwise the only other option is bone marrow transplant and the prognosis with dad’s age and heart isn’t favourable.
I’m just writing here for any support if anyone has gone through this with having heart issues as well and share experiences and advice.
u/Smallfrenchfrychic
Hello all,
My father (66) was diagnosed with PV approx 6 years ago, he was on hydroxyurea and started off having his blood taken out. He suffered a NSTEMI last July and had a double bypass which resulted in gastric ulcer complications and needed 4x blood transfusions.
Fast forward recently cardiologist noted murmur queasy leaky valve and heart failure. Hematologist noted recent blood test showed 3% myelocytes and 7% metamyelocytes in wbc. He was also severely anemic and had a blood transfusion last two days ago. His current symptoms are shortness of breath on exertion, intermittent chest pain, abdominal pain, lethargy, overall unwell feeling, slight pitting oedema in bilateral legs. Last night I noted he had a fever 38.1C and took him to the hospital. They admitted him and his hematologist came in and we’re doing another bone marrow biopsy as he suspects his PV has turned into MF and the leaky valve and heart failure etc may be secondary to the MF. He said he will try him on Jakalvi again even though dad said it made him feel a bit unwell but it might have been the heart issues not the medication. Otherwise the only other option is bone marrow transplant and the prognosis with dad’s age and heart isn’t favourable.
I’m just writing here for any support if anyone has gone through this with having heart issues as well and share experiences and advice.