I did a run with Hanta and kinda freaked myself out
I picked virus, normal mode. I started in Argentina.
I usually don't let the disease get symptomatic until everyone is infected, but I went with cough, nausea, and insomnia when it mutated. I only made it transmissable with ships and rodents.
It took me two years. They almost got me with the cure, but the virus mutated and I just let it go there towards the end.
Kinda freaked me out a little how quick it spread.