My honest experience thus far
I took sema years ago and lost weight. I stopped because I couldn't afford it anymore after I took a break from work when I lost my brother. Now two years later I am hearing great things about tirzepatide and I decided to start back on a GLP-1 and chose tirz. I started tirz in October of 2025, so I have been taking it for about 7 months.
With diet and exercise I have lost a total of 11 pounds. Sure, there's probably some factors involved in that low weight loss but the whole time I'm remembering losing 20 pounds on the sema for the 2 months I took it 2 years ago.
So here's the interesting part. My provider sent me my GLP-1 refill 2 months ago. I was taking it and some weeks later I realized my vials said semaglutide and not tirzepatide. I lost 5 pounds in those two weeks. I called my provider, they apologized and made the order right, they overnights me tirz vials and my weight loss is now back to a halt. So, guess what I'm gonna do...I'm going right back to semaglutide. For me, it has given me the best results. I know it isn't the preferred med for everyone, and also know some have described really bad side effects. But I wanted to share my honest experience thus far and frankly speaking I am glad the provider made the error.