u/Mysterious_Boot_2795

I’m curious about the typical 'endpoint' for testing after a potential exposure. Even with the knowledge that a 4th-generation lab test is conclusive at 45 days and all tests are definitive at 90, many find it difficult to stop testing. I’m interested in hearing how others define the threshold for 'moving on' and how many negative results are generally required to achieve peace of mind.

Struggling to accept test results.

Exposure was August 5th 2025. No new exposures since. No symptoms.

Tested Negative on multiple 4th Generation ag/ab venous blood draw lab based tests:
- 59 days post exposure
- 72 days post exposure
- 88 days post exposure
- 167 days post exposure

Also, received a negative/undetected HIV-1 RNA PCR Quantitative Cobas Roche 6800 test at 177 days post exposure.

Any encouragement or advice is appreciated.

I’m male from the U.S., had unprotected sex with white female. I did NOT take pep or prep. And I did not have not have any new exposures.

HIV testing timeline

Day 59 Post Exposure

4th-generation Venous blood draw lab HIV test: Negative

Day 72 Post Exposure

4th-generation Venous blood draw lab HIV test: Negative

Day 88 Post Exposure

4th-generation Venous blood draw lab HIV test: Negative

Day 167 Post exposure

4th-generation Venous blood draw lab HIV test: Negative

Day 177 Post Exposure

HIV-1 RNA Quantitative Ult (PCR/NAT) Cobas 6800 system: Negative

Should I test again?