u/Important_Account323

Insomnia - 3:30am wake ups

Hey! Been taking metoprolol succinate 25mg at night for about 5 months. I noticed that I wake up at 3:30am regularly and lately I haven’t been able to fall back asleep.

Curious if taking it in the morning instead of at night would make a difference. Has anyone done this? Thanks!

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u/Important_Account323 — 3 days ago

Buspar and gene mutations

Any of you folks on Buspar that have had a gene test as well? I don’t mean GeneSight. I mean a gene test for the MTHFR gene mutations, COMT status, etc.

I have the MTHFR gene mutation as well as slow COMT. Would like to start Buspar but am curious if anyone who has the above gene issues has had success on it or if it adversely affected them? Thanks!!

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u/Important_Account323 — 6 days ago
▲ 3 r/MTHFR

Buspar for Anxiety. Slow (Met/Met)COMT, MTHFR C677T(60-70%) and slow MAO.

Hey everyone! I have the above gene mutations and am interested in adding an anxiety med due to chronic anxiety. I’ve tried SSRIs with basically no luck. My psychiatrist was suggesting Buspar. Has anyone tried Buspar with success? Thanks!

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u/Important_Account323 — 6 days ago

Hey gang! So I’ve had GAD for a long time now. I was on Lexapro for about 7 years then stopped for 2 years. Smoke a ton of pot during and after. Started having bad panic attacks and I was out on an antipsychotic for MDD being how I just lost my 2 month old son. Tried to add a SSRI on top of that and every single one bothered me. Even the ones in the green in my GeneSight test. I have a prescription for Lexapro filled but am scared to take it.

Buspar is also on my green list on GeneSight. The last time I tried it I was also taking the antipsychotic and it was just too much for me. I’m currently no longer taking any medication for depression or anxiety. The depression, through therapy, is very manageable but anxiety is still relatively high.

Am I being ridiculous for being reluctant to try anything at this point?

If I’m going to start it would likely be at 2.5mg twice a day. Has anyone had success on 2.5mg twice a day to start out? Thank you!!

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u/Important_Account323 — 8 days ago

Hello! I’m currently taking metoprolol succinate 25mg for sinus tachycardia. Due to some awful insomnia I am switching to Diltiazem ER 120mg. From what I’ve read I need to wean off the metoprolol as I start the Diltiazem. Is that correct? My cardiologist suggested stopping metoprolol and starting Diltiazem without a wean. Just worried for withdrawal/rebound tachycardia. Thanks!!

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u/Important_Account323 — 13 days ago