u/Good_Suspect_3063

I’m a big noob. I want to hook up these speakers to my PC. I play guitar through an audio interface (pictured) and also want to upgrade my headphones to something that uses a DAC/amp. Maybe some sennheisers or something. Currently using super cheap Logitech ones. How do I achieve hooking up these speakers, my yet to be purchased headphones, and be able to play my guitar through my pc with the least amount of equipment/most efficient way? Sorry for the convoluted question hopefully it makes sense.