Anyone looking at interesting small biotech stories lately?
I’ve been looking at a small company that’s developing a new way to deliver a drug for a hard-to-treat neurological condition. They recently reached a significant milestone with their lead program and expect more updates later this year. It’s still very early stage and obviously high risk.
Anyone else seen any interesting small biotechs with novel delivery approaches or unique mechanisms?
Update: The company I was referring to is NeOnc Technologies ($NTHI).
They are developing NEO100, it's an intranasal (nasal spray) formulation of perillyl alcohol. The idea is to deliver the drug directly to brain tumors, trying to bypass the blood-brain barrier. This is for recurrent high-grade glioma (including glioblastoma), one of the most aggressive brain cancers with very poor prognosis.
What caught my attention:
- Recently completed patient enrollment in their Phase 2a trial.
- Earlier compassionate use and Phase 1/2a data showed response rates better than typical salvage therapies in this setting.
- CEO has been buying shares on the open market (almost $1M in the past year)
It’s still a classic high-risk biotech story, very early stage, cash burn, dilution risk and brain cancer trials have extremely high failure rates. But the novel delivery approach is interesting.