u/EquivalentBest138

If you look at my post over a week ago you could see I started the 3HP version of “PP405” from every chem. the reason I put it in speech marks is because everyone is aware this is just what they hypothesise the molecule to be.

Unfortunately I have bad news. Again, referring back to my last post my issue with every med that had an effect on DHT is gyno. This has always presented the same with all these meds:

1. first sensitivity of only left side breast
2. then swelling and puffiness
3. then actual growth formation

I’ve used this chemical for about a week and from the first day I had the sensetivity just on the left side. I decided to just power through, as a sensation could be a placebo. In the last few days I’ve started to get visible puffiness which I can’t deny, so today I stopped taking it.

Now there’s only 2 theories on why I’m getting gyno from this med

1. there’s an unknown mechanism why trying to stimulate stem cells in the scalp is causing gyno

I’m not sure which is true, but I hope it’s the second one so I still have a chance if PP405 ever gets approved

Anyways, do with this information what you will and I will go back to slowly losing my hair knowing I can’t do anything about it

Also - if anyone in the UK wants to try it, I’m not going to be using it, I’ll be happy to sell it for half the price I bought it for - pm me

TLDR: I’m losing hair and I am not on any other hair loss meds due to their side effects or them not working. I will be documenting my journey using PP405. I also have a beautiful mole near my hairline which is a perfect reference point

HAIRLOSS JOURNEY

- I started losing hair from age 17. I am now 23. For the first 4 years I was the only one that noticed it, but it’s recently got to the point where other people have been pointing it out.

- It started with a receding hairline but now my hair in just generally getting a lot thinner

MEDS TRIED

- I have tried pretty much every single hair loss medication. I’m currently not taking anything. Below is the list of things I’ve tried and why I stopped taking them

1. ⁠DHT meds

- oral finasteride

- Low dose oral finasteride

- Topical finasteride

- Low dose topical finasteride

- Oral dutasteride

- Dutasteride mesotherapy (injected directly into scalp)

- Saw palmetto

- Ketoconozole

- RU58841

- Pyrilatimide / KX826 (topical androgen receptor antagonist)

- every single med I’ve tried where I’ve tried to block the action of DHT has resulted in the same side effect - GYNO

- That’s right, even something as week as saw palmetto gave me the same side effect

- I’ve tried oral anastrazole and topical DHT gel around my areolas to combat this - they didn’t help

- The reasons I know this side effect is not a placebo is because:

1. ⁠I didn’t know this was even a potential side effect when I started

2. ⁠It was confirmed with mammography just on the left side, which is where my symptoms are

- I’ve been trying to figure out why I am getting this effect and how to stop it, and after my years of deep research I’ve come to the following conclusion:

- My tiddies love them some DHT

- So yeah, anything that stops my DHT from working either by lowering the amount or stopping it from binding, even when used topically causes this 1 in a million side effect

2. topical minoxidil with topical tretinoin and microneedling

- Did this for a year with no benefit - no increased shedding at any point and hair loss progressed as same rate so stopped using

- so I’ve been on nothing for my hair for a few months and I’m just watching it slowly go away.

- however I’ve just received my PP405 so I’m going to try document my journey using it and nothing else.

DOCUMENTING

- I will be starting with the first application tomorrow

- attached are the baseline pictures. As you can see I have a beautiful mole near my hairline to track progression

- I will do update pictures in same lighting and location

- I wish I could get a trichometer to make this as objective as possible but unfortunately moneys a bit tight right now. I will be starting my summer job soon, so I may invest in one when I get my first paycheck

- If you don’t hear from me in 2 weeks assume one of 2 things:

- win win either way

Note - on all the PP405 posts, all the comments are ‘that’s not the real PP405’ - we know already, it’s just easier to call it that