u/Elegant_Magician_372

I know there are rare instances where the medicine doesn’t work for someone. However, I was at a ceremony where 2 people had no experience at all, 2 people didn’t have any reaction to it until rounds later (ceremony had three rounds, with largest in round 1). One person immediately got sick from the medicine and didn’t want anymore. Only one person seemed to have a typical reaction. Does this seem normal? I’m wondering if something was wrong with the brew?