u/DuskOfANewAge

This is for people age 40+ without Parkinsons, or 30+ with a diagnosis.

Michael J. Fox has been advertising this on Instagram as part of his Parkinsons research. After signing up and answering basic questions about yourself you will get a package in the mail. This has a pencil and 4 booklets each with 10 scratch and sniff multiple choice questions. You log back into the website and enter the data as you scratch and sniff each page. Trust me when I say many of these questions are very pertinent to whether or not you are identifying the same smells as other cannabis breeders.

I don't want to give away any of the choices because that would influence other people. Let's just say a broad range is covered and you would do yourself some good to see how you interpret them. Worst case scenario you spent some time and helped medical research only to realize you get confused by certain scents. The test only took me thirty minutes.

mysmelltest.org
u/DuskOfANewAge — 13 days ago

https://en.wikipedia.org/wiki/HU-345

I'm curious if anyone else thinks it is perhaps unwise to experiment with such high ratios of CBN in vaporization devices until we know exactly what happens when we do that. Currently only one of the possible byproducts has a chemical name, and we know almost nothing about how it effects humans. I see people making their own mixes with large amounts of CBN, just like the industry is. For edibles and tinctures, fine, since you aren't heating it again to further degrade it.

What concerns me is starting off with an amount of CBN that is many times above what is naturally possible in the plant were it sun dried like people did decades ago (or perhaps in some cultures still) and then heating it again. I feel like products whether professional or homemade should start off mimicking what the plant would produce unless they know it is safe otherwise to go outside those bounds.

For reference CBD degrades to CBE. If you are smoking a type 3/2 a tiny portion will degrade every time. I've experimented some with it, as GVB BioPharma produced a Crystal Resistant Distillate high in CBE and other minors which I've used on rare occasions. I haven't noticed any weird effect from that so far. When I first tried it, I definitely noticed it felt different, and more "whole" than any commercial cartridge I had ever purchased. Obviously I haven't used grams and grams of it, so I can't state for certain it's safe or not, just that I don't notice side effects.

CBC degrades into CBL, some naturally before you've even smoked/vaped it. Again, CBL is a known cannabinoid that was first isolated in the 1960's and you can buy in pure form today if you want to experiment with it. It is suspected to have health benefits, but like many of the relatively unknown minors, nobody seems to be researching it yet.

Now when it comes to CBN, itself already being a degradation of THC, I just don't want to jump to the assumption before we have any actual evidence that whatever it turns into is a useful or positive drug. Wikipedia lists HU-345 as a "non-classical cannabinoid", whatever that means. If any of you have used these products feel free to share your experiences with them. Do you think going above like 2-5% CBN in a vaporizer adds any benefit to the user? How is it different? Have you also tried products that were closer to natural ratios of CBN to THC?

https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.1038729/full

u/DuskOfANewAge — 18 days ago