u/BackgroundSalad1571

Hi all. Long post incoming. I am hoping this community can provide some insight and recommendations. I am based in New Orleans with only two clinic options.

Last year at 41 (husband also 41) I had 4 rounds of IVF. AMH 1.6. Never been pregnant. Never tried naturally- straight to IVF for age purposes. BMI of 20.5

May -Follicular phase Round 1: 5 eggs retrieved/4 mature/3 fertilized - 1 aneuploid (menopur 150)

July -Follicular phase Round 2: 5 eggs retrieved/4 mature - 0 blasts made it today 5 (menopur 225)

September- Luteal phase Round 3: 12 eggs retrieved/9 mature/6 fertilized - 1 segmental aneuploid, 1 chaotic, 1 aneuploid (menopur 150)

December-Luteal phase Round 4: 9 eggs retrieved/6 mature/ - 0 blasts made it to day 5 (menopur 225)

All rounds used Omnitrope during stims only, approx 300 Gonal throughout, dual trigger for all. ICSI and Zymot for all. Acupuncture during two of the rounds.

Taking ubiquinol, fish oil, vitamin d,k,c, prenatal multi, acai, alpha lipoic acid, tru niagen, metformin, inositol, magnesium, 3 mg melatonin, daily zyrtec and flonase (not for fertility purposes).

Husband and I have been alcohol and drug free for 18 months, consistent exercise and daily steps as well as mostly healthy diet. I am trying to cut down coffee - currently at 3 cups per day or so.

  • Since the failed cycle in December, we have switched doctors. I am now on Metformin and Inositol. Husband had surgery for grade 2 varicocele (DNA frag was 23% pre surgery and good semen analysis pre surgery).
  • I also requested a host of bloodwork and found out I am low in iron, iron storage/circulation and B12. Beginning to supplement these as well.
  • We have also had a consult with Dr. Irani at Weill Cornell.
  • A saline sonogram found polyps when we were prepping to transfer our segmental aneuploid in April. I have since had a D&C to remove hyperplasia with atypia.

We are now at a crossroads to do one of the following:

Transfer segmental aneuploid - our clinic here and Cornell encourages whenever ready

Another retrieval locally -not super confident in lab capabilities here

Retrieval in July with Weill Cornell - NYC

I am looking for any advice on protocol, add on's, clinics with success over 40 or anyone who personally used Cornell and feedback on it. Our December round was out of pocket and this next one will be so I am trying to be strategic while knowing I did everything we could before pursuing donor eggs. Such an emotional and expensive journey! Thanks so much.

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u/BackgroundSalad1571 — 12 days ago