When discussing evolution, why do we never consider allostery?
When we discuss evolution, we always discuss phenotypes and genotypes. We also discuss DNA and specific sequence mutations. We know the DNA codes for proteins, and it is these proteins which have function. The modern contemporary view of allostery suggests that most dynamic proteins must be allosteric. It is precisely this mechanism that allows protein function to be more robust to mutations, as well as, allows proteins to evolve. So why is this viewpoint uncommon?