EoT DS4
Hey everyone,
So I just had my EoT scan after 6 rounds of DA-EPOCH-R for PMBCL (going up every round until the last two where I remained on level 5) and unfortunately it’s DS4 and my team is unsure if it’s residual disease or inflammation.
My interim scan (after two rounds) showed 3 spots at ds4 and my EoT only one very small spot but it’s a bit more avid than it was after two rounds. It didn’t grow or anything and also no new lesions (my mass wasn’t very big to begin with, never got told the exact size). They now want to biopsy the spot and radiate it, irrespective of the biopsy results as there’s a chance the biopsy fails because the spot is so small.
My oncologist is very optimistic and thinks radiation will clear it (if it’s even disease), and expects me to be done. If it wouldn’t be enough there is CAR-T but we are not there yet she said.
Clinically my bloodwork looks good (I feel great) and recovering every time (hb is normal range, hasn’t been this way since last summer!)
Any of you who have experienced this (in particular interim to EoT slight SUV increase)? I originally thought DS4 is generally watch and wait. Am I being overtreated by jumping into radiation directly?
I know the DS4 outcomes are very favorable in PMBCL (especially with radiation), and DS4 are common, but I can’t help to feel sad. I don’t know my SUV, my doctor couldn’t tell me just that it is a bit brighter.
Thanks!