r/researchchemicals

It's a tryptamine if the name didn't give that away. I've heard it's way different from typical psychedelics, it puts you into an unconscious state where you can have very vivid hallucinations.

Question in title, I didn’t know these substances were legal nor really knew what they do.

I wanted to know what everyone's go toos are when it comes to anxiety relief and sleep please.

In a few weeks I'm going to a rave from 9pm-4am and then chilling at my friend's house for a few more hours. They'll all be doing mystery cathinones and I usually go sober, but I wanna take something this time and have it actually be worth it, last 3 times I took something were all extremely underwhelming.

Usually I take 2cb, but I only got some bunk >5mg pills that are for a friend, not me and I'm not sure I can get some in time. I do however have a bunch of 1cP/1P-LSD, tho I haven't done it since 2y ago and only 3 times at a rave/festival while otherwise a shit load of times alone. Other options are 4-ho-met/mipt 4-aco-met, amt, AL-LAD, 1cP-MiPLa and LSZ. I'll also have 2 lorazepams with me in case something goes wrong.

Anyone actually taken any of these at a rave, if so how was the experience? Maybe you got other recommendations? Any advice is appreciated!

Edit for grammatical mistakes

Checked a site that sells mostly sells tryptamines and lysergamides, and noticed a few new things. Nitromethaqualone was the first thing that caught my eye, I don't know tons about depressants but I know that its a stronger version of Methaqualone or quaalude, which has a somewhat legendary status.

So far the description seems very good for this product, it was being sold for 70$cad/g which didnt seem bad at all if the active dose is closer to 25mg.

The other products that caught my eye were Bretazenil blotters 0.5mg (60$cad/50 blotters), and Rilmazafone blotters 1mg (60$cad/50 blotters)

I've never done benzos or barbs, but they have always been very interesting for me. I have never purchased them because I only buy online, it never felt worth it to buy and ship a singular xanax, and the price for bulk was a bit too high for me to commit to.

I'm looking for something comfortable and relaxing to use when I'm coming down from stims, or possibly as a combo with weed

It all started with APiHP. I’ll never forget the confusion of learning how to use the oil burner for the first time. My boyfriend at the time vomited after just one hit, despite having an extremely high stimulant tolerance.

I was introduced to an entirely different world — ambition, electrifying happiness, overwhelming joy, vivid colors, phenomenal sensitivity to music and sound. Hit after hit, I had no understanding of how deeply this drug would change and consume my life — or, more accurately, how I would let it consume me. At the same time, I kept convincing myself that my self-control was too strong for addiction.

“Functional addict” — that was the image I had of myself.

I became desperate to isolate myself from the outside world: from work, from family, from making new friends or keeping the old ones. Being unemployed and living alone pushed me into MDPHP addiction frighteningly fast.

I remember losing all pleasure in going outside, in enjoying spring, in watching the trees bloom or feeling warm weather on my skin — because I would keep myself awake and locked in my room for days at a time. Days turned into weeks, weeks into months. Dear God, time flies when you’re smoking pyrros.

The routine never changed. Clean the pipe after the hit. Load the dose again. Take another hit. Hold it in for as long as possible. Exhale. Feel the rush. Lean back for a few seconds — then immediately reach for the pipe again. Over and over. On repeat.

I was constantly paranoid about the windows, terrified that neighbors would see me smoking. I checked endlessly whether the curtains were tightly shut. I locked my doors and stuffed clothes or rags into the gaps underneath them. I burned incense obsessively, spending an extra fifty dollars a month just to hide the unmistakable pyrro smell.

The greatest joy in my day was waking up after a four-day binge and realizing the rush would be stronger because I had managed to sleep for a few hours — usually no more than five or six. I remember taking that first hit and watching my pulse skyrocket on my wristwatch from 60 to 120 BPM within seconds, while I was still holding the smoke in my lungs, nearly fainting from suffocation.

Now, after almost ten months sober, I can say that getting sober has been the hardest and most time-consuming thing I’ve ever done. I still dream about smoking MDPHP — or more accurately, trying to smoke it, but never finding a safe place, never managing to get that hit. The craving in those dreams feels agonizing. It’s pure longing.

My brain transformed those periods of loneliness, worthlessness, and losing myself into something that now feels like nostalgia. That’s what makes it so confusing to live with.

Sometimes life feels even more disorienting now than it did ten months ago. Back then, life was horribly narrow, but it felt focused and simple. Now my mind feels scattered. Troubled.

Sometimes I grieve the fact that I hate being sober.
Sometimes I grieve what this addiction did to my mind.
And sometimes I wonder whether I will ever truly become the person I was before pyrros.

Hiding this sacred secret of mine feels tragically lonely and isolating. I just wanted to share it with somebody.

5mapb is a readily available, grey area legal, for sale on the clearnet in dosed certified tablets, and it’s just flat out better than MDMA aka Molly hence the name Betty. The comeup is joyous; the comedown is sublime and the next day I experience no dip in mood.

"IHCH-7113 is a serotonin 5-HT2A receptor agonist and serotonergic psychedelic of the pyridopyrroloquinoxaline family, derived by structural simplification of the atypical antipsychotic lumateperone. In animal studies, it produced a head-twitch response comparable to DOI or LSD. It is not scheduled in the US or Canada, and no human pharmacology data exists in the published literature."

Possibly a psychedelic, my friend introduced it to me, and I decide to try it. Previously I've only tried DPT, thus I would be able to recognize if it produces a similar effect.

In conclusion, it does.

Here's the full report below:

2026/5/9 20:07 — IHCH7113 Trial

This report documents the subjective experience of an IHCH-7113. 250 mg of the IHCH-7113 (freebase) was dissolved in 100 mL of an PEG400. It didn't dissolve cleanly — estimated concentration is roughly 2 mg/mL. Going by that rough estimate, the total dose accumulated over the session was approximately 10 mg, which should fall within the threshold range estimated from animal studies (5–20 mg).

20:07 — 1 mL. No effect.

20:56 — 1 mL. No effect.

21:49 — 3 mL. A bold redose with exponential logic. As I'd later understand, this initiated a complete (was it truly complete?) psychedelic trip — somewhat different in character from the familiar mushroom or ayahuasca experiences.

22:14 — Took a hot shower — which may well explain the physical sensations that followed.

22:22 (+/−) — Racing thoughts. Familiar worries circling back, alongside a fear of the unknown — after all, this isn't a substance that's been used by the likes of Shulgin, Nichols, Bluelight, or the r/ResearchChemicals community. That set an uneasy tone from the start.

22:35 (+/−) — Persistent goosebumps, accompanied by noticeably negative thoughts. No visual hallucinations; no auditory changes. Overall sensory perception remained intact. A flood of memories surged up. I began to lean toward thinking the problem wasn't entirely the substance itself, but rather my own psychological reaction to it. Started recalling a bad experience with gaboxadol. Things were still looking grim.

22:43 (+/−) — Memories keep surfacing. A bad, deeply uncomfortable feeling. Tried listening to music to steady myself and considered putting on headphones — but still couldn't calm down, kept asking myself obsessively: "What is actually wrong?"

22:44 (+) — Shortly after the shower: mild nausea, along with an intense heat sensation — not a gentle warmth, but a heat from somewhere deep inside. Without a thermometer I couldn't tell whether my temperature was actually elevated; a quick hand-to-forehead check didn't suggest it was. The hot shower likely compounded the physical discomfort that followed. I started to wonder whether this wasn't purely the substance, but also my own mental state playing a role. Still, the absence of any hallucinations was unsettling.

23:10 (++) — The heat intensified significantly, accompanied by shivering. Since it persisted, I got up to turn on the air conditioning. What followed was a compulsive, repetitive fixation on "heat" — the chat logs show me typing "so hot" over and over, which tells me the sensation had become the absolute center of my consciousness, overwhelming everything else.

Reflecting on it afterward: this is similar to some of the reports in PiHKAL — whatever your mind locks onto becomes amplified. The hot shower seeded that physical anchor, and it just kept growing — which may say more about priming than about the substance's inherent properties.

23:33 (++) — An inexplicable urge to smile, or an involuntary smile appearing on my face — even as the heat still dominated my awareness.

23:35 (++) — Cognition clearly altered, starting to feel fragmented. Still wasn't sure whether the substance was actually working. In hindsight, this was obviously not mere placebo suggestion.

23:43 (++) — Eyes closed: imagery of multi-legged, long-limbed, segmented worm-like forms; the structural formula of phenethylamine; expanding ripples spreading outward.

23:50 (++) — Heat still unrelieved despite the AC. Laughing involuntarily.

23:58 (++) — Clear open-eye visuals beginning. The throw pillow in front of me appeared pixelated.

00:00 (++) — Staring at my hand and its scars: the hand's appearance began to shift — colors deepening, its sense of presence flickering, fading in and out.

00:03 (++) — Difficulty focusing. If I didn't actively try to focus, my visual field seemed to tremble. The heat, still inescapable.

00:07 (++) — More classically psychedelic imagery emerged: ornate patterns, floating geometric shapes, rainbow-like colors. The visual changes seemed tied to how I directed my eyes and adjusted my focus — I kept experiencing this as though I were turning some kind of dial, fine-tuning the effect.

00:10 – 02:00 (++ / +++) — My thoughts began to be carried away by the psychedelic state. A sense of curiosity and wonder toward everything around me. The heat kept returning in waves, but the emotional undercurrent began to noticeably shift. The heat was still there — but being overwritten by more interesting and engaging experiences.

Visuals became increasingly interactive during this phase: ordinary shapes seemed to be automatically organized into symbols, colors, patterns, and dynamic structures, all highly responsive to where I directed my attention.

The worm-like figures grew eyes and wings, and I found myself feeling genuinely happy. The earlier negative imagery was reinterpreted with a lighter, even endearing quality. The heat hadn't left — but emotionally, I was in a very good place, carried along by anime-adjacent imagery and cute, whimsical things.

02:00 – 02:40 (++) — Coming down gradually. Feeling a little sleepy. All in all, a pleasant journey — with a noticeable antidepressant quality. On the whole, this seems like a substance with mild psychoactive effects and a moderate duration. Still unclear whether the heat sensation is an intrinsic property of the substance or something the hot shower had triggered.

02:40 – 03:40 (+) — Pupils still dilated. Body still warm. But — goodnight.

Hey everyone,

Me and my friends usually take MDMA on special occasions. Most of the time we do one initial dose and a redose later, which has been enough for us to enjoy a full night out (normal party + a few hours of afters). It’s been consistent for us - good vibes, dancing, talking, and a smooth night overall.

Recently I started reading about 4-MMC and got curious about it. I’ve never tried it before, and I’m thinking about whether it could be a good alternative for a night like this.

We wouldn’t snort anything, so it would be oral only.

What I’m trying to understand from people who have experience:

How does 4-MMC feel compared to MDMA in a club/techno setting?

How does redosing typically work with it ? is it even similar or totally different from MDMA?

Does it actually last long enough for a full night + afters, or does it drop off too fast?

Is it generally more “party-friendly” or more chaotic/compulsive than MDMA?

Would you personally recommend trying it for a birthday night out, or is it better to stick with MDMA if we already know it works for us?

The plan would be: club around 11pm → dancing/talking until ~2am → afters (techno/electronic) until 5–6am → head home.

I’m a bit unsure and honestly a little nervous about changing something for a special night, especially since it’s my friend’s birthday and I don’t want to risk ruining the vibe.

Would really appreciate honest experiences and thoughts from people who’ve actually tried both.

I have always avoided this group of substances because I did not need anything stronger than 2MMC - oral 250-375MG was for me top bliss.

That is why I preferred it to NEP, I like NEP but I did not want to use it when 2MMC was fully sufficient for me.

I would be interested in how it is with anxiety and psychosis with pyrovalerones, I love that they relax me with stimulants - I have ADHD, depression, anxiety disorder and anhedonia, and they do not even get rid of it and for a while I feel great, I love to live, unfortunately these substances are not available after blanket ban

do pyrovalerones have this effect at the beginning at a "reasonable" dose? or is anxiety present from the beginning or only in the comedown or redosing, because stimulants like 2MMC remove my anxiety, they relax me, they open me up and I feel physical and psychological euphoria, is there anyone here who knows and likes 2MMC and then tried pyros?

of course it is an incomparably stronger group of substances than any 2MMC, but I am wondering if I would like something with the effect of MDPHP, because now a substance has appeared that I will be researching that should have a rush like mdphp - supposedly, and I don't really know what to expect from it, I love dopamine stimulants, but I have slight doubts whether it will be too strong a caliber for me, what do you think?

Did you do research on alpha-PVP and bought it or you were offered this shit? Did you know that it’s Flakka/alpha-PVP beforehand, and still took it? Or you just smoked it without knowing and was hooked? I’m so freaking confused how anyone would willingly get within 10000 kilometers of this drug.

P.S: this is out of curiosity and not judgement.

Hi all,

I've just noticed you can buy 4-mmc (mephedrone, right?) online through websites that sell research chemicals. But I thought 4-mmc was classified as an illegal substance in Europe.

Is it the same or what's the catch? This way would be cheaper than from a dealer and I would be sure about the quality. And it's delivered at home, it sounds too good to be true, and if it seems too good, it mostly is. That's why I'd like your input.

I hope this kind of post is allowed here, if not, I'm terribly sorry, but could you point me to where I could ask this?

Anyway, thanks in advance!

Well, is it?

After the analog act passed I was sure I'd missed my opportunity. Now, there's seemingly a new scene popping up, and even more blunt and bold with how "out in the open" and easily accessible some of these are right now.

Has the RC scene been resurrected for a while?

I decided to try memantine with my friend. We both had a terrible experience with that never-ending dysphoric feeling. People were saying music appreciation goes to an extreme peak, but it sounded even worse than when sober. I kept puking every hour—the most unique but also the most horrible trip I have ever experienced to date. It’s been more than 24 hours now, and I’m still nauseous, have a headache, and still feel a bit high. But boy, oh boy, it made me rethink every life decision, my addiction, and for sure it will have an impact on my future subs use. I had never gone a day without smoking weed, no matter how high, sick, or ill I was. But I haven’t smoked even cigarettes for these two days. I would not recommend memantine to anyone at recreational dosages. If you got any questions about my experience feel free to ask !!

I’m a longtime fan of 3-MMC; when I started exploring RCs the legit stuff could be ordered on the clearnet, while 4-MMC that everyone spoke of so nostalgically was extinct. I began using 3-MMC as a sex enhancer, primarily in combo with GBL but sometimes alone.

I’ve used what I had very sparingly and I’m down to my last ~500mg. How times have changed… Now it’s 3-MMC that is basically extinct, while 4-MMC can be sourced again, and there is also the weak sister, 2-MMC (which I don’t think is terrible, just not what 3- and 4- are). I’ve acquired some of both.

And that got me wondering… What would a blend of all three be like? I’m thinking of maybe a 2:1:1 ratio of 2- to 3- and 4-, wondering if there would be a synergy together that might possibly be more that any of the three on its own. I mean, it works for grape varietals going into a good Bordeaux…

Anyone tried something like this?

I’m attending EDC this weekend and I plan to take psychedelics all 4 days. I want to take

ETH-LAD, 4-HO-MET, 25B-NBOH, and 2C-B.

I suppose I’ll go in order of increasing tolerance formation, but I need help with a dosing regimen. I want a moderate trip on each day. What order should I take these, and at what dosages to overcome tolerance?

(I’ll also be mixing in ketamine and maybe some 3,4-MD-PCP as I see fit.)