r/pssdhealing

Improvement in PSSD Symptoms After St. John’s Wort (SJW) – My Experience So Far

Improvement in PSSD Symptoms After St. John’s Wort (SJW) – My Experience So Far

Hi, 32M here.

I developed what appears to be PSSD after taking Escitalopram for around 8 months in 2024. After withdrawal, I experienced:

Complete loss of libido

Erectile dysfunction

Weak orgasm

Reduced semen volume

Emotional blunting

My labs at that time showed:

LH and FSH at the lower edge of normal

Testosterone below normal range

I tried many supplements and eventually Clomiphene citrate. Testosterone increased, but symptoms barely changed. Some supplements gave mild improvement, but nothing major.

Later I tried inositol, which completely crashed me again.

Then used, bupropion but its effects diminished, I used only 75mg.

Recently I decided to carefully try St. John's wort because I had read mixed experiences online and was honestly scared to use it. I started slowly and have now been taking 1000 mg daily (morning and night) for about two weeks.

So far I’ve noticed:

General physical health improvement

Skin tone returning closer to normal

Full morning erections returning

Better erections during sex

Stronger orgasm sensation

Slight increase in libido

Increased semen volume

More enjoyment and emotional response during intimacy

This is the first thing since withdrawal that has produced noticeable changes beyond just testosterone numbers.

I know two weeks is still early, and I understand SJW can also affect serotonin systems, so I’m being cautious. My plan right now is:

avoid adding multiple supplements

continue stable dosing

focus on sleep, exercise, and recovery

monitor for any crash or emotional changes

Has anyone else with SSRI-induced sexual dysfunction or PSSD experienced improvement from SJW? Especially regarding:

libido

genital sensitivity

orgasm quality

emotional connection

erectile function

Would appreciate hearing long-term experiences, positive or negative.

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▲ 13 r/pssdhealing+1 crossposts

Genome test findings

So, i have been posting in the dr powers section, and working with that community. They requested we get certain testing done to learn about pssd, and maybe form patterns. I did full test panel, dutch test and genome.

I discovered that, i have issues metabolizing antidepressants. I have various genes that are causing this. So essentially, i've been screwing myself up with zoloft for 20yrs, leading to pssd. Take that for what its worth, and i'd be interested to see, if others have these same gene issues. Maybe somethung to test for.

How to fix it now, i don't freaking know.

u/Professional_Gur2905 — 6 days ago
▲ 11 r/pssdhealing+1 crossposts

Did someone got there genitals shrink very bad, and recoverd or at least got better? My numbness is getting better, libido too, but my genitals feels like they getting smaller every month. Anhedonia and emotional blunting its getting up and down. I am a girl. Take care 🤍

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u/Correct_Total8918 — 14 days ago

Has anyone recovered from fluoxetine-induced PSSD?

Just wondering if theres any difference in recovery from different medications. I havent seen too many stories of recovery from fluoxetine-induced PSSD, and just wondering if anyone can give me a bit of hope.

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u/billieeilishstyle_ — 13 days ago

Getting ability to sex after eating goat meat

Been off meds since 2 years...when i eat goat meat I get aroused for sex and good morning wood....sexual dysfunction gone....what made goat meat to do so ?.....do I have any deficiency so that goat meat is helping?

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u/Dangerous_Peace6334 — 13 days ago