I’ve been on seroquel for treatment resistant anxiety and depression for 4 years. I have no libido from it. I’m looking to switch to Caplyta to see if my libido returns.
Hi guys, I have been on Caplyta for 3 months and it’s been a lifesaver. I take it at bedtime and sleep well for the most part, although I’ve been waking several times through the night lately. Initially I did notice a little unsteadiness while walking when I first woke up but that’s mostly passed.
My question is, have you gotten less than 8 hours and had any side effects? My job wants me to take a red eye to NY which leaves at 12:30 am (way later than I would normally take it) and lands at my equivalent time of 8:30 am. However I do have a stop as well. And I would pretty much need to hit the ground running when I got there. So I’m a little concerned about my capacity to function.
Would you take it right before the flight and hope the 4ish hours before the layover is enough and then I can hopefully catch another hour or so on the second leg. Thanks for any advice!
This is the third mood stabilizer I’ve tried now. I’ve (27m) been in almost every SSRI in the book. Antipsychotics. You name it. But this mental anguish I’ve had the last 13 years is too much. Will this finally help me feel better? I feel like I have nothing. All my meds have given me increased anxiety and depression. Have fucked with my libido making dating impossible. I have social anxiety. I have trouble being alone. I’ve been on Wellbutrin 300xl once daily and lamotrigine 300mg once daily and that was the closest I’ve gotten to feeling “better” but then it all went to shit again and the meds stopped working. My doctor says I may have treatment resistant depression. I’ve tried ketamine therapy. Ive tried everything possible to help. Had this medicine helped anyone?
I starred Caplyta 42mg once daily on Monday. My side effects I feel have been odd. Im looking for some insight.
My side effects have been nausea, fatigue, feeling very cold, and body aches.
Anybody else have these?
my (estimated) co pay with this new order jumped up considerably through CVS. has this happened to anyone else? do i need to be worried moving forward?
sorry if against rules im just freaking out
I’ve been on Caplyta (42 mg) for Bipolar Depression type 2 for about a year now and it’s been working great. In that time I’ve been diagnosed with ADHD. I was on Adderall for three days, and then went off it immediately as it started to cause severe suicidal ideation. Since then, I’ve been scared to try other types of ADHD medication.
For people with Bipolar and ADHD, what combinations with Caplyta have worked for you?
I started on Caplyta a little over a month ago. Prior to starting I was dealing with major depression and general apathy. I took 21mg for one week and then went up to 42mg for 2 weeks. I started feeling better even after 3-4 days on the 21 mg and about 3 weeks in I was feeling incredibly energized, motivated, and so much happier. I did not feel manic, I just felt like myself again. However, it got to the point where I was feeling very overstimulated and my mind was racing, so I ended up going back down to 21mg since I felt like it started working when I was still on 21mg. I was on 21mg for 2 weeks and I feel like it did not work at all and I am back to feeling depressed and hopeless. I went back up to 42 mg starting 5 days ago but so far I still feel the same. I am scared that starting Caplyta triggered a manic episode and that I won't be able to get that feeling back...has this happened for anyone else?
I started on 10.5mg for a week and I am now on day 5 of 21mg. I take it at night and every single night after I have taken this medication I have been hit with dizziness, extreme sedation and confusion. There has not been a single night that I have not. It feels like a brain injury or something. It lingers into the morning for a few hours as well. I wake up sort of shaky, confused and still dizzy. I’ve noticed I am forgetting a lot of things and my partner has been concerned. Last night I had the worst night so far. It hit me like a truck and I genuinely felt like I was super drunk. I was slurring my words really bad and falling over. My nose was also super stuffy and could barely breathe. I wanted to try and power through these effects even tho they have kind of scared me but at this point idk if it’s worth it. A lot of what I have read have been the first few days or week. But I’m going on week 3 soon and Idk if I can keep feeling this way. it only seems to be getting worse at this point. Has anyone else had a similar experience this far in ? Did it ever get better ? Or did you have to come off the medication?
TLDR: Would you consider it a red flag that a doctor would start you on a high dose of Caplyta without mentioning any negative side effects may occur? Especially when you are med sensitive and have expressed that?
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I guess I’m having trouble trusting my instincts lately, mainly because I’m severely depressed and anxious. I’ve been this way for a while. In my entire medical history prior to being placed on Caplyta, I was on one AP (Abilify) and I was on the lowest dose available as an adjunct to my antidepressant. I’ve actually been told by my primary doc that the dose was too low for me to even notice it.
Well fast forward, new doctor, aware I tried that combo in the past and aware it didn’t work for me. She made the decision after I wasn’t getting better on my med regimen to have me quickly taper my antidepressant (Auvelity) and place me on 21mg of Caplyta, with the expectation that I would titrate up to 42mg in just two days. I am diagnosed with Major depression and anxiety. No other mood disorders. The only thing she told me when I started Caplyta is that she think it may help with my depression and that it is “great” for anxiety and sleep. Trust me, I asked plenty of questions.
Well, I ended up having a HORRIBLE reaction to Caplyta. From this thread alone I know this is not uncommon either. Stuck it out for 7 days before I couldn’t take it anymore. She’s out of town so the on call doc told me to just stop, no tapering. Now I just feel angry. I feel like I am 10x worse off than I was before this medication change. I know there is trial and error involved in my diagnosis but I think what bothers me the most is that I have emphasized to her several times how scary med changes are to me and how apprehensive I was about this switch. She never once mentioned any negative side effects. Even the minimal ones people report.
I’m thinking it’s time for a new doctor but I thought I’d see what other people that have to go through several drug trials think. Especially those on Caplyta.
I appreciate that she has tried me on medications I’d never tried and I will acknowledge she’s very quick to respond to concerns I have. I just feel like there is now a lack of trust I’m not sure I can shake.
**Just want to add: I hope my experience doesn’t scare anyone interested in the drug. I’ve read here that several people thrive on it. It just wasn’t for me.**
Update: He finally connected with his psych and she agrees that the symptoms are concerning. After discussing the pros and cons of going completely off Caplyta, she's giving him samples of a lower dose for a few weeks while he follows up with his PCP about getting specialist appointments and further blood testing. So that's a step in the right direction. He thinks the severe abdominal pain this AM may have been prompted by feeling a bit better over the last few days and experimenting with foods his GI tract wasn't ready for. He's going back to liquids for a few days. Just trying to reduce the variables as much as possible.
Orig. Post: I posted a couple of weeks ago that overall, my husband's experience has been positive, while I've been withholding judgment. Just a few days later, things took a pretty weird turn. He has been recovering from an episode of diverticulitis that left him hospitalized for 4 days. Since then, he's had to return to the ER twice. The first time it was renewed abdominal pain - they checked everything and said it was dehydration and released him. The second time (a few days after my last update) he was having weird chest pain and went to urgent care, they did an EKG and said it was abnormal so he needed the ER. Frankly the ER treated him very poorly, but one new symptom he had been experiencing along with the chest pain (a new symptom they entirely ignored) was that the blood vessels in his arms were overly swollen, his hands were swollen and beet red (including the palms) and severely itchy. When the nurse attempted to put an IV in, the blood vessel sprayed like a firehose. She said she'd never seen that in 12 years of nursing. Anyway at the ER they redid the EKG and did a chest xray and said it was probably an electrolyte imbalance and sent him home.
The next couple of days he would have a flareup of this weird new symptom every time he took Caplyta. I had been wondering for weeks if Caplyta was somehow inhibiting his recovery from his illness, and had suggested a couple of times that he should ask his pysch about this possibility, but he had been resistant. Now with this new freaky symptom, he was finally ready to consider that it might be Caplyta, but it was now the weekend and he couldn't reach his psych to ask, so he decided to simply test out not taking it for one night. That night his arms and hands did not puff up and while they were mildly itchy, it was bearable. The following day he slept about 20 hours, but said it felt like restorative sleep. He skipped Caplyta a second night, and no recurrence of the symptom. Slept 20 hours the next day too, and had a pretty bad headache, but continued to say he was feeling like his body was recovering. Skipped Caplyta a third night. Still hadn't heard anything from his psych despite reaching out a couple of times via text.
The next day his energy was continuing to come back... but so was depression rearing its ugly head for the first time since beginning to take Caplyta. We both panicked a little bit, and that evening he decided to take it again. I suggested dumping out half the capsule for a half dose, but he decided to just take the whole. Next day (yesterday), his gut pain was back and so was the sense of being parched and unable to quench his thirst, which had been relieved when he didn't take it those couple days. I believe he took it again last night. This AM, he is in agony with severe abdominal pain and urgent trips to the restroom - much worse than the original onboarding of the drug.
So... we are in a pickle. I know we need to reach out to his psych and pester her until she responds, but there are many other things going on - trying to schedule various specialists to follow up on his gut issues, other family members hospitalized, one car totaled and a second car possibly a loss as well, substance abuse by young adult kids... it just feels like the last month has been one long lightning-and-hail-storm. We can't keep all the balls in the air we are juggling. It's clear Caplyta has a noticeable effect in keeping him non-depressed AKA psychologically functional. But if it is causing physical debilitation, it's a wash. IDK.
Any advice to make this easy? I’m starting at 21 mg. I have severe emetophobia and I’m terrified of starting new meds. I’ve heard so many good things and want this to be positive for me.
I am on day 2 of 42mg and it has been a terrible, horrible,no good, very bad 2 days. I take it at night. Day 1 I woke up feeling drunk and spent the whole day napping on the couch. I basically slept for 32 hours. Day 2 I felt a very teeny bit better, possibly because I already slept so much. But I was still unable to function more than the absolute bare minimum. I definitely have not been safe to drive. I also feel like I urgently need to pee. I've read that some people become incontinent. I am not ok with that. I am discontinuing the med until I can talk to my doctor about lowering the dose. I want to go down to 10.5mg because I don't think 21mg will be enough to improve the side effects because they are so intense.
Has anyone had experience getting off Caplyta after extended use? I'm worried that if starting it is this hard, getting off of it will be a nightmare.
I’ve been on Caplyta for awhile now but ever since I’ve started taking it, I get hot really easily and sweat more than usual. Summers are especially brutal. I can’t be in the sun for too long for I’ll feel like I’m on the verge of a heatstroke.
Hi everyone, I have successfully been on Caplyta for about 25 days!
I have been more motivated to get back into old hobbies, clean, etc. I do have side effects still, like brain fog, and my anxiety has been more prevalent unfortunately (especially the physical symptoms- breathing funny, body going numb). Beside that, my blood pressure has been good, no headaches. I have to go get blood work/general checkup to make sure my levels are fine and what not, just to ensure the medicine isn't doing anything bad lol.
Anyway , I will be going up to 21mg this Wednesday, and was curious if side effects would come up again? I'm mostly dreading that splitting headache I got the first day on Caplyta 😩 I was shaking from the pain and wanted to puke lol. I can tolerate sleepiness but the headache is the one I fear. I'm also worried that my anxiety will get worse :/ I take hydroxyzine as needed but I try not to take it since it makes me soooooo drowsy.
Thanks!
Quick edit: I have GAD as well, so the Caplyta has been exasperating the anxiety a bit 😬
I just got prescribed Caplyta 10.5mg by my new psychiatrist. I really like her, which is saying a lot because I haven't liked any of my previous psychiatrists! I have been on 15+ meds for my depression and bipolar, but I have never tried this one...With that being said, I am supposed to take my 4th dose tonight. The side effects so far have been, well, hell lol.
I'm not sure if the grogginess and overall feeling of being unwell have affected my mental state, or if that is also happening. But simply put, I am very depressed and moody. I have little moments throughout the day where I feel decent, but that fades quickly. I want to push through, but it's really difficult, given that I'm a new mom. I would love to hear if it gets any better, so please share your experiences if you take/have taken this!
Is anyone getting financial assistance with being able to afford this drug? And if so where are you getting it from? I really would like to try this medication but cant afford it through insurance. Anybody have any ideas on where i can get it more affordable?
Ive been on caplyta 21mg for bp2 for 1 month and dont notice any difference. Ive been stuck in the same intense depressive episode since February and I started it 1st week in April. Do I keep taking it or js move on? I don’t even know if it’s worth it anymore since I feel no difference. Ik I gotta give it time and shi but I can’t keep js taking this and living through this depressive episode with no changes or at least hope for a med to finally work for me. How long did it take for u guys? Ig I js need some advice rn bc I’ve been on 9 different meds and still haven’t found anything helpful. My current cocktail is lithium 900mg, Prozac and caplyta. I js don’t know wa to do anymore I’m so tired and feel so discouraged and hopeless.
Hi, I have been taking Caplyta for 5 weeks now. Started out with severe dizziness and sedation but not able to sleep. That continued but I felt energetic so I have been trying to push through the fatigue, nausea, tremors and insomnia. Now I am feeling horrible. I am depressed and crying all the time. Just hit me suddenly that this is what bi-polar is but I am not bi-polar. I feel like I am in a black hole, not able to move or get myself out. It's a Saturday and I am just lying here not knowing what to do and just wanting it all to go away. I feel so disappointed in the medication and in myself.
I take the 10.5mg caplets, my psychiatrist said that she wants to go to the 20mg. I've been waking up between 3-6 am and not been able to get back to sleep. Should I start the 20mg dose tonight?
Hi, so I've been on caplyta for about 7 years or so. I was initially started on 42mg because that was the only dosage available. At first I had no side effects and genuinely felt that the medication was helping me quite a bit. I've noticed over the past 2-3 years it's just not the same anymore and I have a lot of the side effects. I officially stopped the caplyta last night. Yesterday morning I started vraylar. It was horrible so I have no intention of taking it again, so I am essentially going cold turkey with caplyta.
Last night withdrawal began almost immediately with racing thoughts and just noise and too much energy in my head. It took me forever to initially fall asleep. I did not go into a deep sleep and was at least 50% conscious the whole night. At around 4:30am it all suddenly stopped and I think I might've gotten some REM sleep but honestly I'm not sure. I had a vivid dream of my house flooding and then next thing I knew, my alarm went off.
Upon getting up, I felt really out of it. Like a mix of low blood pressure and low blood sugar, so kinda like dizzy, intense brain fog, my head would start pounding like I wasn't getting enough oxygen to my brain. I get ready for work in slow motion and leave.
I got to work and ate my breakfast. All felt ok in regards to my mood and and my ability to hold conversations. Soon after, my head starts feeling like I'm developing a migraine. I took advil and that seemed to make it go away for now. The longer I've been awake, the more I twitch. It's mainly just in my face and fingers, though.
I am currently considering trying to take a nap at my desk during my lunch break but I'm not sure if I'll be able to. Overall my brain fog has gone down but on a scale of 1-10 with fatigue/sleepiness, I am at a 10. Last time I felt this tired I had stayed awake for 36 hours straight. I will update some more later today and over the weekend. My Dr said the caplyta should only be in my system for like 4-6 days because of its short half life so hopefully this is the worst of it.
EVENING After I got home from work, I laid in bed and just kinda dissociated to Whatnot streams for a couple hours. When I got up I can say I felt oddly rested? I made some food but wasn't able to finish it due to severe cramps and bloating. I took an edible and ended up spending the rest of my waking hours watching diy videos lol
DAY 2 I took melatonin last night around midnight and slept about 5 hours straight but woke up due to stomach issues. I'm genuinely not sure if I'm tired or not. I went back to sleep somewhat after the stomach issues subsided, but I know I was constantly trying to get comfortable and that wasn't happening. Like my eyes feel and look tired, but my body and mind are rearing to go. This is as of officially getting up for the day at 10:30am. My mind wasn't racing as bad earlier this morning so that was nice. This has been the first time in years that I've taken melatonin and I'm not completely zombified with exhaustion to the point of sleeping 15+ hours the next day.
I was expecting significantly worse withdrawal considering I've actually experienced worse withdrawal from caplyta years ago. Being that it hasn't been working like it used to, I wonder if my body's just not reacting as intensely to being without it? I am used to dealing with constant severe fatigue, so I'm not sure how to react to getting less sleep and having more energy. I'm gonna go cook breakfast, and I guess I'll see how I hold up today in regards to energy.