r/NeurophysiologyGroup

▲ 2 r/NeurophysiologyGroup+1 crossposts

Optimizing Action Potential Peak assignment in HD-MEA set-up

Hi to everybody. I am proceeding with the analysis of data coming from HD-MEA recordings. During the spike detection analysis I have to set parameters such as peak lifetime period, refractory period and also filter parameter, high pass or band pass filter, selecting a specific cut off, and also some filters such as IIR or FIR. My aim is to collect the action potential shpaes that have to be align at the same point. Sometimes the algorithm is not able to precisely assign the negative peak and take a peak just before or after the real peak. I have a biological background and if someone of you can help me in understaing how to use these filter to I will be very grateful.

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u/No_Background_9834 — 6 days ago