Hello, I’ve been on xolair for over a year now. I have MCAS and it helped me be able to eat more and get from 60 mgs of prednisone to 4 mgs. After a few months even I tolerated smells like perfumes which is a huge trigger for me. I take300mgs twice a month. Now starting in the beginning of the fall I stopped being able to eat foods that became safe again. And also since I work in a k-8 and the kids are getting stinky there’s sooooooo much perfume and it’s killing me. My kids last year were kind about it but these kids are not. like my throat gets tight I start getting swollen hard time breathing etc. I asked
My doctor why was it was much better before, is my Xolair not working , and she said it’s something that will fluctuate and Xolair isn’t really for that . I have a litany of antihistamines I take when it happens but if
I’m just being continually exposed there’s only so much I can do.
I asked if I needed a higher dose and she said She also said sh want to go higher than 300 as that’s the recommended dose for angioedema / anaphylaxis.
Has anyone ever noticed a decreased efficacy or feeling like it’s just not working as much anymore?