Immunotherapy (keytruda) or Vaccine (Dendritic Cell) with first line of treatment
My mom (56) got diagnosed with grade 4 GBM in March, unmethylated. Has anyone added any immunotherapy drug or Dendritic cell therapy with their first line of treatment? My mom had currently started her 45 day cycle of RT+TMZ.
We are based out of India. We are two siblings, I (29) am in academics (urban planner) and my younger sibling (26) is a doctor (OBGYN). Both of us are very research heavy in our work and has dived into on-going trials / TTF / Vaccines around the world pretty much like any other caregivers. In our country we do not have many on-going trials except for TMH (which my mom doesn’t qualify for) but there are many ongoing studies in private hospitals here which offers individual therapy/vaccines such as Dendritic Cell Therapy.
Current status of our mom: she recovered quickly from the resection surgery. We bought her home in 3 days of the operation and she could walk, bathe herself, talk, play the usual games on her phone, within 3 days of the surgery. 🧿🧿🧿 She is on her 7th day of radiation and she is feeling a bit weak but is still continuing her routine. 🧿🧿🧿The only problem she still has is her missing vocabulary. She cannot remember colours or what she has for her last meal.
My sister and I because of our mom’s unmethylated result of the biopsy and her current physical and medical status are pushing the doctors to give us a heads up for either of the above stated treatments. Till now we have met top oncologist in our country and all of them have asked us not to integrate such treatments.
Has anyone been through something similar? Is it wise to against their doctors? Since we are coming from a country where government is not interested in medical advancement and our best option is to go for private clinics, should we go for alternate treatments along with FDA approved line of treatment?
Thank you in advance!🫂