u/poly_cherry

I am planning to go for the big panels - Somascan 11k or OLink Explore HT (~5.3k) for my CSF samples. Somascan's menu is more accessible and gives detailed QC metrics for all their proteins - and has a good hit rate of my proteins of interest. OLink is a bit more opaque about the performance of sepcific proteins. I am also leaning more towards Somascan as it is larger and offers it as a service and charges per sample (instead of plate).

Apart from logistical advantages - why should anyone choose one over the other. Anyspecific downsides of somascan? Can the aptamer be reliably trusted to be specific? Anyone having any good/bad experince with CSF proteomics using these 2 methods?

Need to make a proper decision as it is quite some money!

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u/poly_cherry — 13 days ago