Keytruda - Immune Colitis/Related symptoms?
I’ve been having issues on my 400mg/6 week dose of Keytruda. I have done 3 rounds of it so far, since I finished my 5 cisplatin, 25 radiation, 5 brachy and 200mg/3week dose of Keytruda during that time. The first one gave me major issues (diarrhea, abdominal pain and once in a while nausea) for a couple weeks). I had issues eating stuff that would agree with my GI tract.
I had major life changes within a week after that treatment (broke up with boyfriend of 3+ years, week later my dog was diagnosed with a brain tumor and passed a week after that, then other more typical life challenges). I thought maybe the major stress from all that with it made it worse.
During that time, I tried 6 day steroid pack which didn’t help. Then was on 40 day steroids. It was rough. It helped during (minus the side effects being difficult) but diarrhea started coming back after. I had Keytruda last week and this week had terrible diarrhea again, almost went to the ER and am on 30 day dose of steroids again. 😞
They’ve said dropping to 200mg/3 week dose may not change anything and have mentioned potentially stopping treatment but need to talk further. Has anyone else had issues similar? I still have 14 cycles left and unsure what that would mean for me and reoccurrence.
For background, I was diagnosed stage 3c in September. Was cleared with NED end of March. I am a very healthy 36F otherwise. I’ve really struggled not being able to eat my typical foods, having to constantly focus on rice, bread, chicken etc with no veggies or fruits.
Thank you!!