u/littlepup26

I was started on LDN for fibromyalgia 4 weeks ago. I compound it at home (to save money, I lost my job 6 months ago) following my doctors instructions, crushing the pill into a fine powder and mixing with equal parts purified water, then once the filler is all settled down overnight I draw from the water with a syringe and shoot that positively nasty tasting medicine into the back of my throat so I don't gag on the taste.

I was started on 1mg and I had side effects in the beginning like nausea, appetite loss, and some more vivid dreams at first. All of that tapered off within two weeks. Then I increased to 2mg at the 2 week mark and the first night I had drenching night sweats but no side effects since then. In one week I will increase to 3mg.

I don't feel any symptom improvement of any kind yet, I might as well be drinking sugar water, and that is making me worried maybe somehow I did something wrong. I have OCD, which really doesn't help my feeling that maybe I fucked something up. I double triple checked everything though, I did the 1:1 ratio as instructed, I think I did everything right.

Is it possible that it could be less effective when compounded at home? Or do I need to trust the process and keep pushing on to see if it eventually works?

I started at 1mg, after two weeks I moved up to 2mg, and a week from tomorrow I will increase to 3mg. When I first started it I definitely had side effects like nausea, lack of appetite, and a bit more vivid dreams, but those have all tapered off by now. As far as pain management goes, it is doing absolutely nothing, I might as well be shooting apple juice down my throat instead of LDN. Was anyone's experience similar? I feel like I always read people saying they at least felt something by this point. Regardless, I plan to continue taking it until my doctor and I decide otherwise as I'm running out of medication options.

I'll try to keep this short but after ten years of working in kitchens, most recently as a manager and cake decorator, I developed a neuro-inflammatory chronic pain disease and lost most of my mobility. Then in September I lost my job. I can't work in kitchens anymore because I can't walk very much, I need a job where I can sit as much as I need to without having to ask for accommodations to allow me to sit. I tailored my resume to focus on the administrative and customer service aspects of my experience and I've mostly been applying to front desk/reception positions, always targeting new listings, and being sure to use AI filter terms in my resume. After applying for over 200 jobs I had four vet reception interviews, 2 physical therapy office interviews, and a holistic medicine office interview. No one hired me. I need other job options to apply to so I can increase my chances of being hired, but I genuinely don't know what to apply for other than reception/front desk in various medical fields. Hotel reception is a no go, they have you on your feet in those jobs.

I already tried working with vocational rehabilitation through my state to try and get connected with jobs, as I have a disability and those services are covered by Medicaid, but those services are completely useless in this job market. The counselor listened to my job search experience thus far and then proceeded to pull up Indeed in front of me and start doing exactly what I told her I've already been doing.

If anyone has any ideas on job titles I can search for, companies I should apply to, anything at all, I would greatly appreciate it. I've hit a wall.

edit: I forgot to mention, please don't recommend I apply for disability, that's a several year long process and right now I'm simply focusing on finding work.

I became disabled last year and lost my job/career. I was a baker and a cake decorator and started to get sick in September of 2024. I spent September 2024-September 2025 underemployed (workers comp, then unpaid FMLA, then part time work) before losing my job in Sept 2025. I was diagnosed with a neuro-inflammatory chronic pain disease with no cure and very few viable treatments. I'm currently taking the last medication option available to me and am still waiting to see results.

Since losing my job in September I have applied to around 250 jobs, gotten maybe 8-10 interviews, and no one has hired me. I need a job where I can sit down as much as I need to with minimal walking required, so my options are severely limited. I tailored my resume to focus on customer service (and to get through AI screenings) and I've been applying mostly to front desk and reception positions, but I still mask for covid because I am immunocompromised now, and I'm finding that once employers see me in person they no longer want to hire me. They want a smiling, fully visible face at the front desk and I can't provide that.

I tried working with my states Division of Rehabilitation Services, but after I explained my situation to them all they did was pull up Indeed and start sending me listings for the exact types of jobs I told them I had already been trying and failing to get. Then they suggested I volunteer in an office to get office experience. I stopped working with them after that.

I had to take a month off from applying for jobs because it was giving me intense suicidal ideation, but then my unemployment ran out March 20th so yesterday I hopped back on Indeed for the first time. It was so bleak it actually made me want to kill myself. I very seriously thought about swallowing all of the pills in my cabinets until eventually I just ended up on the floor crying for an hour. I'm 35 and I never thought I would end up here. I live alone and have no one to help me and I can't find work.

I had saved up money while I was still working with the intention of going to school to become a med lab scientist, and now that money is going to my rent and living expenses. I'm at a place now where I'm trying to decide if I want to continue the job hunt and move forward living off my savings, or move back in with family at 35 and finish school.

If you had asked me in 2024 if I would ever move back in with my family in the suburbs, I would have laughed in your face. Now I think about it constantly. I just see no way out of this where I'm at. I don't want to move back there, but I don't know what else to do.

I lost my career to fibro about seven months ago. I was diagnosed in July and out of my job by September. Since then I've applied to around 300 jobs, had maybe 10 interviews, and no one has hired me. I can't work in my field anymore and I need a job where I can sit down as much as I need to, so my options are very limited, and in this job market transferrable skills aren't getting me anywhere.

I had to take a break from applying for jobs for about three weeks because it was decimating my mental health. I just went back on Indeed yesterday to try applying again, and it was so fucking bleak I genuinely wanted to die, like I really considered swallowing all of the pills in my apartment but ended up crying on the floor for like an hour instead.

I want to go back to school to work in a medical lab, which I would physically be able to do, and I actually saved money for the last 8 years with the intent of going back to school. Now that money is going towards my rent and living expenses because I have no income coming in. I'm in a really hard place right now. I don't know if I should keep spending my savings on rent while I try to find work, or if I should throw in the towel and move back in with family in the suburbs while I finish college. I'm about to turn 36 and the idea of moving back in with my mom would have been completely absurd before I developed fibro. Before fibro I would have told you there was no way in hell I would ever move back there. But here we are. I just don't know what to do, I've been underemployed since September 2024 (I was on workers comp for four months, then off work unpaid for a month, then just part time), I've been unemployed since September 2025, I'm just exhausted and sick of being stuck in this place where I'm not making any progress and I'm just...rotting.