Seizures on the very last day of Radiotherapy/TMZ - Stable CT but high edema. Looking for experiences.
Hi everyone,
My mother (GBM Grade 4) was supposed to have her very last (30th) session of radiotherapy today. However, she had two focal seizures last night, about an hour apart. We rushed to the hospital and she is currently admitted.
The Current Situation:
• CT Scan Results: The doctors said the tumor is stable and hasn’t grown since the start of treatment. However, the scan shows significant edema (swelling) and a slight midline shift in the surgery area.
• Clinical Progress: Before the seizures, she was doing great. Her consciousness was clear, her "confabulations" had stopped, and she started regaining movement in her paralyzed left arm and leg. She can even hold a small ball with her fingers now.
• Symptoms: She currently does NOT have a fever. She had some transient swelling in her left hand/foot about 2 weeks ago, but that has completely resolved.
The Plan:
The doctors postponed the last radiotherapy session for now. They are focusing on managing the edema with IV fluids/steroids and adjusting her anti-seizure medication (Keppra).
Has anyone else experienced seizures specifically at the very end of radiation despite clinical improvement? Does this sound like "Pseudoprogression" or just treatment-induced inflammation?
I would appreciate any comments, similar experiences, or advice you can share. Thank you so much.