Need help with Agilent 6460A LC-MS no-power issue
Hi everyone,
We’re looking for advice from anyone experienced with the Agilent 6460A LC-MS or similar 6400-series systems.
We’ve been troubleshooting this instrument for about 2 months and still can’t get it running, even with help from an “expert” over WhatsApp.
Initial symptom: when plugged in, only the turbo controller showed power: two green lights. Pressing the front power button produced no normal startup: no other lights, no fan, no rough pump, no obvious relay click.
What we’ve tried:
Replaced the AC board with a new one.
Bought and installed a third AC board.
Replaced fuses.
Tested wall power.
Used a power conditioner set to 230 V.
Tried a UPS/battery backup.
Tested the roughing pump power outlet with the system “on”: no voltage.
Checked the front power-button connection.
Checked wiring/connectors as best we can.
Odd recent behavior: one time, a fan briefly kicked on when powered up. After turning the system off and back on, the fan did not come on again.
Questions:
If the turbo controller has green lights but the rest of the MS seems dead, what would you check next?
Should the rough pump outlet receive voltage immediately, or only after an internal startup condition?
Are there common interlocks, relays, low-voltage supplies, or enable signals that prevent startup?
Has anyone seen this exact failure mode?
We’re not trying to bypass safety systems. We’re trying to understand where the power chain is stopping.
Any advice would be appreciated.