u/buttercup2227

Got calprotectin results and colonoscopy today, left with more questions than answers

I recently posted about how after being diagnosed with UC at age 4, having since been in remission for 15 years or so (for the most part), ive started having what seems to be a very uncomfortable flare a couple months postpartum at age 25. Now for several weeks my subjective experience was BRUTAL; bad stomach cramps, fatigue, blood and mucus in almost every BM, tenesmus, pretty much constant diarrhea. 2-3 weeks into flare i was finally seen by a new GI who ordered infectious disease panel and calprotectin. Around that time and since it has still been very uncomfortable but improving. Infectious panel negative. Today i both got calprotectin results and had colonoscopy done...Calprotectin was borderline at 100, and colonoscopy showed "granularity in rectum" and "patchy erythema across entire colon" but most concentrated in distal portion. GI doc said "it certainly does not look normal but I do not know whats wrong" and took biopsies of rectum, each colon segment, and end of small intestine. Says histopath results should come in a week. Honestly frustrating for me because subjectively ive *FELT* terrible, but objective test results seem mild so to speak. GI doc seemed very competent and I got the impression she found the findings abnormal but not particularly concerning. Im at such a loss...I know theres *something* wrong but it seems she doesn't think UC is back since according to her "calprotectin is usually exponentially elevated and not just doubled" in IBD and that colonoscopy showed inflammation/bleeding/redness but not severe to the point of total ulceration..

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u/buttercup2227 — 11 hours ago