Possible issues with Calquence after 18 months?
My husband has had CLL for 10 years. He’d been doing really well managing it with general rest, exercise, lack of stress, etc, and his numbers were floating around 5-7k. He was put on Calquence in Dec 2024 - spleen had enlarged to 20cm. He had a rough time at first, but his body adapted and he’s been doing pretty well for the first 12-14 months. Lymphocytes exploded, then were down to 7k in march, then he picked up a cold or something (we both did, took a few weeks to feel better). Since then, he’s just been exhausted, run down, stomach issues, and very much not himself. Did bloodwork last week, lymphocytes up to 8.3k. Not a big jump, but I’m concerned about his overall health right now.
Does anyone have similar issues with Calquence? We thought we were in the home stretch and that he’d be able to stop taking it in the next 3-6 months.