u/Zapp1982

Interday standard curves have wildly different response factors. What gives?

Interday standard curves have wildly different response factors. What gives?

As the title suggests, these are the same standards ran 2 days apart on a GC/MS Agilent 7890 gc connected to a 5975C MS. DB5ms column, brand new septum and liner. I get good linearity, just not good repeatability.

EDIT: This trend shows the response factor growing over time, previous studies have shown it also shrinks. Slope increases over time then decreases over time repeating.

u/Zapp1982 — 6 days ago