u/UnlikelyCycle2447

Hello,

We've been seeing oncologists for my aunt (69yo, TNBC, stage 1 but multicentric with tumor sizes: 2.3 cm and 1.2cm, no underarm lymph node involvment, treated with surgery then reduced chemo:weekly cycles of reduced taxol carboplatin, has diabetes).

One oncologist suggested to also give her adjuvant immunotherapy (pembrolizumab) after a full cycle of chemotherapy not the reduced one. All this after mastectomy without node involvment. She chose the reduced chemo though. I see pembro is common in neoadjuvant setting (when started before surgery not after).

Does anyone have a similar experience getting immunotherapy after already having surgery followed by chemotherapy in early stage TNBC? Any ideas, suggestions?

Hello,

We've been seeing oncologists for my aunt (69yo, TNBC, stage 1 but multicentric [tumor sizes: 2.3 cm and 1.2cm] , no underarm lymph node involvment, treated with surgery then reduced chemo [weekly cycles of reduced taxol carboplatin], with diabetes).

One oncologist suggested to also give her adjuvant immunotherapy (pembrolizumab) after a full cycle of chemotherapy not the reduced one. All this after mastectomy without node involvment. She chose the reduced chemo though. I see pembro is common in neoadjuvant setting (when started before surgery not after).

Does anyone have a similar experience getting immunotherapy after already having surgery followed by chemotherapy in early stage TNBC? Any ideas, suggestions?

Hi all. I'm wondering whether starting to use cold freezing gloves and footwear after the 4th cycle of adjuvant chemo could still be useful to prevent/reduce chemotheray induced neuropathy?

9-12 weekly cycles of reduced dosage of taxol and carboplatin are planned for my aunt (69yo, TNBC, muticentric stage1, diabetic). The meds are given intravenously via one hand (not mastectomy side). She's already on a daily (higher than drugstore) dosage of neurobion pills (vit B1, B6 and B12) to prevent simple neuropathy.

Any ideas? Thoughts? Similar experiences? Also, would using such gloves while being on IV still be possible?