u/Spittinfacts100

Hey everyone,

I’ve been diagnosed with Ankylosing Spondylitis and I’m HLA-B27 positive, but lately my rheumatologist thinks I may actually have psoriatic spondyloarthritis / axial PsA because I seem to have overlapping symptoms from both conditions.

I have bilateral sacroiliitis with chronic inflammatory lower back pain, and during bad flares the pain and stiffness spread into my upper back and neck as well. I also deal with severe morning stiffness, fatigue, shoulder joint pain, finger joint pain, mild heel pain while walking, and psoriasis mainly on my feet.

I started treatment with Remicade (Infliximab), then switched to Simponi, and later went back to Remicade because the response wasn’t as effective as it should’ve been. Unfortunately I’m still struggling a lot and right now the pain and stiffness are pretty severe. Because of the psoriasis along with the axial symptoms and peripheral joint involvement, my rheumatologist now wants to switch me to Tremfya.

I’m honestly confused because my spine and SI joint symptoms feel very AS-like, but the psoriasis and other symptoms point more toward PsA. Has anyone else here had a similar overlap situation or been diagnosed with axial psoriatic arthritis / psoriatic spondyloarthritis?

I’d really appreciate hearing from people with similar experiences, especially if you’ve used Tremfya. Did it help your SI joint pain, neck stiffness, fatigue, or overall inflammation? Did TNF inhibitors stop working well for you too?

This condition has become very painful physically and mentally, so I’m just trying to understand where I fit and what treatments helped others in similar situations. Basically what's wrong with me?!!!

Thanks in advance.

Hey everyone,

I’ve been diagnosed with Ankylosing Spondylitis and I’m HLA-B27 positive, but lately my rheumatologist thinks I may actually have psoriatic spondyloarthritis / axial PsA because I seem to have overlapping symptoms from both conditions.

I have bilateral sacroiliitis with chronic inflammatory lower back pain, and during bad flares the pain and stiffness spread into my upper back and neck as well. I also deal with severe morning stiffness, fatigue, shoulder joint pain, finger joint pain, mild heel pain while walking, and psoriasis mainly on my feet.

I started treatment with Remicade (Infliximab), then switched to Simponi, and later went back to Remicade because the response wasn’t as effective as it should’ve been. Unfortunately I’m still struggling a lot and right now the pain and stiffness are pretty severe. Because of the psoriasis along with the axial symptoms and peripheral joint involvement, my rheumatologist now wants to switch me to Tremfya.

I’m honestly confused because my spine and SI joint symptoms feel very AS-like, but the psoriasis and other symptoms point more toward PsA. Has anyone else here had a similar overlap situation or been diagnosed with axial psoriatic arthritis / psoriatic spondyloarthritis?

I’d really appreciate hearing from people with similar experiences, especially if you’ve used Tremfya. Did it help your SI joint pain, neck stiffness, fatigue, or overall inflammation? Did TNF inhibitors stop working well for you too?

This condition has become very painful physically and mentally, so I’m just trying to understand where I fit and what treatments helped others in similar situations.

Thanks in advance.