u/Snaphappy3

Curious if anyone has any experience with using chlorthalidone to treat proteinuria? My doctor took me off Farxiga today as it had no impact on the protein spillage after an 8 month trial. In fact my eGFR fell from 88 to 69 during this period. My ACR didn't move and urine protein increased, so she changed my meds to Chlorthalidone and cancelled me taking Hydrochlorothiazide. In addition to this, I am also on Ramipril and Amlodipine for hypertension.

I had high hopes for Farxiga but it looks like it isn't helping me. Just curious if anyone has had positive results on chlorthalidone?