u/Rosegirl310

Image 1 — I just need help, I’m losing hope.
Image 2 — I just need help, I’m losing hope.
Image 3 — I just need help, I’m losing hope.
▲ 11 r/MTHFR

I just need help, I’m losing hope.

Short but long story.

  • Mental breakdown in Jan 2024
  • Diagnosed with Autism Dec 2024
  • Several unsuccessful attempts to try new psych meds after coming off the same SSRI I was on for 20 years (since I was 9) from March 2024 to now.
  • Genesight test results in November 2025 (pic attached) COMT is Val/Met
  • Bloodwork done before supplementing (pic attached)
  • Tried Methyl Folate (NOW brand) low dose 250mcg in the morning, had to stop after a week due to severe side effects. Felt back to “normal” after stopping.

I was recommended to start Folinic Acid with B12 instead. I understand that the added B12 is essential even if I have normal B12 levels.

My question is what the heck do I take? What Dosage? What kind? Best brand? Start slow and go up? I need affordable options, preferably something I can get on Amazon. No health insurance. I’m going to lose my mind and give up eventually. Thank you for your time. Please be gentle with me, I’m a fragile person. And yes, I intend to keep having my blood work checked consistently.

u/Rosegirl310 — 2 days ago