u/Physical-Patience668

At my wits end with side effects

I have been on GLP1s since the end of 2022. They have been life changing for me. I had no problems with side effects until the end of 2024. Since then it has been a nightmare. It is confusing because I tolerated both Zepbound and wegovy for several months with no problems.

I was on Zepbound from 2024-April 2025. I began having intermittent diarrhea that progressed to incontinence and diarrhea several times a week by the beginning of 2025. I even had a colonoscopy and was tested for gluten intolerance. Both were normal.

I took a break from meds until September and started wegovy. I went up on dose very slowly. I was tolerating 1.7mg well until 2 months ago. The diarrhea started again. At first i thought maybe it was just from greasy or fatty foods. Over the last month i have been meticulous about my eating and I’m still having diarrhea 2-4 days a week with much less frequency and no incontinence.

Just to be sure I got blood drawn and I’m getting a complete abdominal ultrasound to check my gall bladder.

I am now down to my last option of trying Saxenda (liraglutide) but am just tired at this point. I also just saw the new oral drug Foundayo that just came out.

TLDR I have had massive health benefits from taking GLP1s but am exhausted from the diarrhea. Do any of you have experience with liraglutide or know if the foundayo have less GI side effects?

Thanks for letting me vent.

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u/Physical-Patience668 — 15 hours ago