gut issues / histamine / weight loss = im lost
Hi everyone,
I’m posting here because I’ve been dealing with severe health issues for about 1.5 years now, and I honestly don’t know what to do anymore. I’m hoping someone here recognizes this or can point me in the right direction.
Background
My problems started around 1.5 years ago while I was using:
• Finasteride
• Minoxidil
Things got significantly worse when I later took Accutane.
Then at the end of August, I had a confirmed STEC bacterial infection (food poisoning), and since then everything has escalated badly.
Main symptoms
Whenever I eat foods high in histamine, I get strong reactions:
• Skin rashes
• Heart palpitations
• Anxiety / panic-like feelings
Other symptoms I’ve developed over time:
• Severe bloating and gas (especially with foods like banana, bread, mushrooms, apples, grapes, beetroot)
• Constipation
• Constant gut rumbling (especially small intestine area)
• Very low libido (went from daily to almost none)
• Insomnia
• Dry skin
• Sweating
•. Low libido
•. Weight loss 52kg I came from 58kg
I also lost a lot of weight and my face looks very pale/grey.
Medical tests
2x negative sibo test
Microbiome test = realy high bifido bacteria and low butyrate ( see pictures)
I’ve had a lot of testing done.
Endoscopy + biopsies:
• Mostly normal findings
• Mild, non-specific inflammation in the ileum
• Lymphoid aggregates in colon (no active disease)
• No Giardia
• No signs of celiac or major structural disease
Blood tests:
• Low IgG
• Low IgG2
• Low IgA
• Elevated creatinine
Abdominal ultrasound:
• Normal
Gut / microbiome findings
• Diagnosed with “leaky gut”
• Microbiome test showed high Bifidobacteria
• Strong reactions (gas/bloating) to certain carbs/fruits
⸻
Strange reaction to treatment
In January I tried:
• Allicin
• Oregano oil
• Strict diet
What I suspect
I’m really unsure, but I’ve considered:
• MCAS (mast cell activation syndrome)
• SIBO / dysbiosis
• Post-infectious gut damage (after STEC)
• Immune dysfunction (low immunoglobulins?)
It feels like something is wrong in the end of my small intestine (ileum).
😞 How it affects me
This has completely taken over my life:
• I barely sleep
• My libido is gone
• Eating feels stressful instead of normal
• I feel like my body is constantly reacting to everything
I’m honestly exhausted and just want to understand what’s happening and how to heal